Integration of PKR-dependent translation inhibition with innate immunity is required for a coordinated anti-viral response

PRRs are watching you: Localization of innate sensing and signaling regulators

(2015) Jonathan Chow et al.   VIROLOGY

Stress Granules Regulate Double-Stranded RNA-Dependent Protein Kinase Activation through a Complex Containing G3BP1 and Caprin1

(2015) Lucas C. Reineke et al.   mBio

IPS-1 plays an essential role in dsRNA-induced stress granule formation by interacting with PKR and promoting its activation

(2014) P. Zhang et al.   JOURNAL OF CELL SCIENCE

The Stress Granule Protein G3BP1 Recruits Protein Kinase R To Promote Multiple Innate Immune Antiviral Responses

(2014) Lucas C. Reineke et al.   JOURNAL OF VIROLOGY

Activation of Stress Response Pathways Promotes Formation of Antiviral Granules and Restricts Virus Replication

(2014) D. K. Rozelle et al.   MOLECULAR AND CELLULAR BIOLOGY

Antiviral innate immunity and stress granule responses

(2014) Koji Onomoto et al.   TRENDS IN IMMUNOLOGY

DHX36 Enhances RIG-I Signaling by Facilitating PKR-Mediated Antiviral Stress Granule Formation

(2014) Ji-Seung Yoo et al.   PLoS Pathogens

Strategies of highly pathogenic RNA viruses to block dsRNA detection by RIG-I-like receptors: Hide, mask, hit

(2013) Luca Zinzula et al.   ANTIVIRAL RESEARCH

Mapping the crossroads of immune activation and cellular stress response pathways

(2013) Nuno Cláudio et al.   EMBO JOURNAL

Cytosolic Sensing of Viruses

(2013) Delphine Goubau et al.   IMMUNITY

Biphasic RLR-IFN-  Response Controls the Balance between Antiviral Immunity and Cell Damage

(2013) S.-Y. Hwang et al.   JOURNAL OF IMMUNOLOGY

MDA5 Localizes to Stress Granules, but This Localization Is Not Required for the Induction of Type I Interferon

(2013) M. A. Langereis et al.   JOURNAL OF VIROLOGY

Production of a Dominant-Negative Fragment Due to G3BP1 Cleavage Contributes to the Disruption of Mitochondria-Associated Protective Stress Granules during CVB3 Infection

(2013) Gabriel Fung et al.   PLoS One

Diversion of stress granules and P-bodies during viral infection

(2013) Lucas C. Reineke et al.   VIROLOGY

Innate immune responses to DNA viruses

(2013) Ying Nie et al.   Protein & Cell

Dynamic Oscillation of Translation and Stress Granule Formation Mark the Cellular Response to Virus Infection

(2012) Alessia Ruggieri et al.   Cell Host & Microbe

Protein Kinase PKR Amplification of Interferon β Induction Occurs through Initiation Factor eIF-2α-mediated Translational Control

(2012) Christopher S. McAllister et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Large G3BP-induced granules trigger eIF2α phosphorylation

(2012) Lucas C. Reineke et al.   MOLECULAR BIOLOGY OF THE CELL

Critical Role of an Antiviral Stress Granule Containing RIG-I and PKR in Viral Detection and Innate Immunity

(2012) Koji Onomoto et al.   PLoS One

Protein phosphatase 1 subunit Ppp1r15a/GADD34 regulates cytokine production in polyinosinic:polycytidylic acid-stimulated dendritic cells

(2012) G. Clavarino et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of stress granules in virus systems

(2012) James P. White et al.   TRENDS IN MICROBIOLOGY

Stochastic Expression of the Interferon-β Gene

(2012) Mingwei Zhao et al.   PLOS BIOLOGY

Induction of GADD34 Is Necessary for dsRNA-Dependent Interferon-β Production and Participates in the Control of Chikungunya Virus Infection

(2012) Giovanna Clavarino et al.   PLoS Pathogens

Orchestrating the interferon antiviral response through the mitochondrial antiviral signaling (MAVS) adapter

(2011) S Mehdi Belgnaoui et al.   CURRENT OPINION IN IMMUNOLOGY

Coronavirus Gene 7 Counteracts Host Defenses and Modulates Virus Virulence

(2011) Jazmina L. G. Cruz et al.   PLoS Pathogens

Peroxisomes Are Signaling Platforms for Antiviral Innate Immunity

(2010) Evelyn Dixit et al.   CELL

mRNA escape from stress granule sequestration is dictated by localization to the endoplasmic reticulum

(2010) H. Unsworth et al.   FASEB JOURNAL

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

(2010) Taro Kawai et al.   NATURE IMMUNOLOGY

Role of PKR and Type I IFNs in Viral Control during Primary and Secondary Infection

(2010) Yumi Nakayama et al.   PLoS Pathogens

Mechanisms of Protein Kinase PKR-Mediated Amplification of Beta Interferon Induction by C Protein-Deficient Measles Virus

(2009) C. S. McAllister et al.   JOURNAL OF VIROLOGY

Uncoupling Stress Granule Assembly and Translation Initiation Inhibition

(2009) Sophie Mokas et al.   MOLECULAR BIOLOGY OF THE CELL

Reprogramming mRNA translation during stress

(2008) Satoshi Yamasaki et al.   CURRENT OPINION IN CELL BIOLOGY

Induction of Protein Kinase PKR-dependent Activation of Interferon Regulatory Factor 3 by Vaccinia Virus Occurs through Adapter IPS-1 Signaling

(2008) Ping Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The RNA-activated Protein Kinase Enhances the Induction of Interferon-β and Apoptosis Mediated by Cytoplasmic RNA Sensors

(2008) Christopher S. McAllister et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Control of Cellular GADD34 Levels by the 26S Proteasome

(2008) M. H. Brush et al.   MOLECULAR AND CELLULAR BIOLOGY