Genome-wide host RNA signatures of infectious diseases: discovery and clinical translation

Scaffolding and completing genome assemblies in real-time with nanopore sequencing

(2017) Minh Duc Cao et al.   Nature Communications

Target-Induced and Equipment-Free DNA Amplification with a Simple Paper Device

(2016) Meng Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Diagnostic Test Accuracy of a 2-Transcript Host RNA Signature for Discriminating Bacterial vs Viral Infection in Febrile Children

(2016) Jethro A. Herberg et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Association of RNA Biosignatures With Bacterial Infections in Febrile Infants Aged 60 Days or Younger

(2016) Prashant Mahajan et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Direct Comparison of Alere i and cobas Liat Influenza A and B Tests for Rapid Detection of Influenza Virus Infection

(2016) Frederick S. Nolte et al.   JOURNAL OF CLINICAL MICROBIOLOGY

A nucleic acid strand displacement system for the multiplexed detection of tuberculosis-specific mRNA using quantum dots

(2016) H. D. Gliddon et al.   Nanoscale

Real-time, portable genome sequencing for Ebola surveillance

(2016) Joshua Quick et al.   NATURE

Electrochemical detection of nucleic acids, proteins, small molecules and cells using a DNA-nanostructure-based universal biosensing platform

(2016) Meihua Lin et al.   Nature Protocols

Mobile real-time surveillance of Zika virus in Brazil

(2016) Nuno Rodrigues Faria et al.   Genome Medicine

Genome-wide expression for diagnosis of pulmonary tuberculosis: a multicohort analysis

(2016) Timothy E Sweeney et al.   Lancet Respiratory Medicine

Developing a Clinically Feasible Personalized Medicine Approach to Pediatric Septic Shock

(2015) Hector R. Wong et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Ultrasensitive Electrochemical Detection of Nucleic Acids Based on the Dual-Signaling Electrochemical Ratiometric Method and Exonuclease III-Assisted Target Recycling Amplification Strategy

(2015) Erhu Xiong et al.   ANALYTICAL CHEMISTRY

Mind your P's and Q's: the coming of age of semiconducting polymer dots and semiconductor quantum dots in biological applications

(2015) Melissa Massey et al.   CURRENT OPINION IN BIOTECHNOLOGY

Human Gene Expression in UncomplicatedPlasmodium falciparumMalaria

(2015) James M. Colborn et al.   Journal of Immunology Research

Multiplexed Homogeneous Assays of Proteolytic Activity Using a Smartphone and Quantum Dots

(2014) Eleonora Petryayeva et al.   ANALYTICAL CHEMISTRY

Evaluation of Alere i Influenza A&B for Rapid Detection of Influenza Viruses A and B

(2014) Shuping Nie et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Decoding long nanopore sequencing reads of natural DNA

(2014) Andrew H Laszlo et al.   NATURE BIOTECHNOLOGY

Spatially resolved transcriptomics and beyond

(2014) Nicola Crosetto et al.   NATURE REVIEWS GENETICS

Diagnosis of Childhood Tuberculosis and Host RNA Expression in Africa

(2014) Suzanne T. Anderson et al.   NEW ENGLAND JOURNAL OF MEDICINE

Comparison of the Abbott m2000 RealTime CT Assay and the Cepheid GeneXpert CT/NG Assay to the Roche Amplicor CT Assay for Detection of Chlamydia trachomatis in Ocular Samples from Tanzania

(2013) L. Dize et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Integrated RNA extraction and RT-PCR for semi-quantitative gene expression studies on a microfluidic device

(2013) Kirsty J Shaw et al.   LABORATORY INVESTIGATION

Detection of Tuberculosis in HIV-Infected and -Uninfected African Adults Using Whole Blood RNA Expression Signatures: A Case-Control Study

(2013) Myrsini Kaforou et al.   PLOS MEDICINE

Whole Blood Gene Expression Profiles to Assess Pathogenesis and Disease Severity in Infants with Respiratory Syncytial Virus Infection

(2013) Asuncion Mejias et al.   PLOS MEDICINE

RNA-seq and microarray complement each other in transcriptome profiling

(2012) Sunitha Kogenaru et al.   BMC GENOMICS

Optical imaging techniques for point-of-care diagnostics

(2012) Hongying Zhu et al.   LAB ON A CHIP

Rapid point-of-care detection of the tuberculosis pathogen using a BlaC-specific fluorogenic probe

(2012) Hexin Xie et al.   Nature Chemistry

Dual RNA-seq of pathogen and host

(2012) Alexander J. Westermann et al.   NATURE REVIEWS MICROBIOLOGY

Host response transcriptional profiling reveals extracellular components and ABC (ATP-binding cassette) transporters gene enrichment in typhoid fever-infected Nigerian children

(2011) Sok Kean Khoo et al.   BMC INFECTIOUS DISEASES

Computational methods for transcriptome annotation and quantification using RNA-seq

(2011) Manuel Garber et al.   NATURE METHODS

A window into third-generation sequencing

(2010) E. E. Schadt et al.   HUMAN MOLECULAR GENETICS

Au-nanoprobes for detection of SNPs associated with antibiotic resistance inMycobacterium tuberculosis

(2010) Bruno Veigas et al.   NANOTECHNOLOGY

An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis

(2010) Matthew P. R. Berry et al.   NATURE

Application of nanostructured ZnO films for electrochemical DNA biosensor

(2010) Maumita Das et al.   THIN SOLID FILMS

Gene Expression Patterns of Dengue Virus-Infected Children from Nicaragua Reveal a Distinct Signature of Increased Metabolism

(2010) P'ng Loke et al.   PLoS Neglected Tropical Diseases

Nano/Microfluidics for diagnosis of infectious diseases in developing countries

(2009) Won Gu Lee et al.   ADVANCED DRUG DELIVERY REVIEWS

Gene Expression Signatures Diagnose Influenza and Other Symptomatic Respiratory Viral Infections in Humans

(2009) Aimee K. Zaas et al.   Cell Host & Microbe

Microarray Analysis of Lymphatic Tissue Reveals Stage-Specific, Gene Expression Signatures in HIV-1 Infection

(2009) Q. Li et al.   JOURNAL OF IMMUNOLOGY

Quantification of the yeast transcriptome by single-molecule sequencing

(2009) Doron Lipson et al.   NATURE BIOTECHNOLOGY

Transcriptional response in the peripheral blood of patients infected with Salmonella enterica serovar Typhi

(2009) Lucinda J. Thompson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Point-of-Care Diagnostics for Global Health

(2008) Paul Yager et al.   Annual Review of Biomedical Engineering

Using fluorescent nanoparticles and SYBR Green I based two-color flow cytometry to determine Mycobacterium tuberculosis avoiding false positives

(2008) Dilan Qin et al.   BIOSENSORS & BIOELECTRONICS

RNA-seq: An assessment of technical reproducibility and comparison with gene expression arrays

(2008) J. C. Marioni et al.   GENOME RESEARCH

The potential and challenges of nanopore sequencing

(2008) Daniel Branton et al.   NATURE BIOTECHNOLOGY

Direct multiplexed measurement of gene expression with color-coded probe pairs

(2008) Gary K Geiss et al.   NATURE BIOTECHNOLOGY