An R848 adjuvanted influenza vaccine promotes early activation of B cells in the draining lymph nodes of non-human primate neonates

Distinct TLR-mediated cytokine production and immunoglobulin secretion in human newborn naïve B cells

(2016) Matthew A Pettengill et al.   Innate Immunity

Whole-Virion Influenza Vaccine Recalls an Early Burst of High-Affinity Memory B Cell Response through TLR Signaling

(2016) Taishi Onodera et al.   JOURNAL OF IMMUNOLOGY

A Novel R848-Conjugated Inactivated Influenza Virus Vaccine Is Efficacious and Safe in a Neonate Nonhuman Primate Model

(2016) Beth C. Holbrook et al.   JOURNAL OF IMMUNOLOGY

Adjuvanting an inactivated influenza vaccine with flagellin improves the function and quantity of the long-term antibody response in a nonhuman primate neonate model

(2016) Beth C. Holbrook et al.   VACCINE

Inclusion of Flagellin during Vaccination against Influenza Enhances Recall Responses in Nonhuman Primate Neonates

(2015) Jong R. Kim et al.   JOURNAL OF VIROLOGY

In vivo characterization of the physicochemical properties of polymer-linked TLR agonists that enhance vaccine immunogenicity

(2015) Geoffrey M Lynn et al.   NATURE BIOTECHNOLOGY

Nonhuman primate infants have an impaired respiratory but not systemic IgG antibody response following influenza virus infection

(2015) Beth C. Holbrook et al.   VIROLOGY

Activated Human Neonatal CD8+ T Cells Are Subject to Immunomodulation by Direct TLR2 or TLR5 Stimulation

(2014) M. McCarron et al.   JOURNAL OF IMMUNOLOGY

T Regulatory Cells Contribute to the Attenuated Primary CD8+ and CD4+ T Cell Responses to Herpes Simplex Virus Type 2 in Neonatal Mice

(2014) M. A. Fernandez et al.   JOURNAL OF IMMUNOLOGY

Unleashing the potential of NOD- and Toll-like agonists as vaccine adjuvants

(2014) C. Maisonneuve et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tracking and quantification of dendritic cell migration and antigen trafficking between the skin and lymph nodes

(2014) Michio Tomura et al.   Scientific Reports

The Dendritic Cell Lineage: Ontogeny and Function of Dendritic Cells and Their Subsets in the Steady State and the Inflamed Setting

(2013) Miriam Merad et al.   Annual Review of Immunology

Utilizing bacterial flagellins against infectious diseases and cancers

(2013) Shirin Tarahomjoo   ANTONIE VAN LEEUWENHOEK INTERNATIONAL JOURNAL OF GENERAL AND MOLECULAR MICROBIOLOGY

The use of Toll-like receptor 7/8 agonists as vaccine adjuvants

(2013) John P Vasilakos et al.   Expert Review of Vaccines

B Cell-Intrinsic TLR7 Signaling Is Required for Optimal B Cell Responses during Chronic Viral Infection

(2013) J. M. Clingan et al.   JOURNAL OF IMMUNOLOGY

CD64 Expression Distinguishes Monocyte-Derived and Conventional Dendritic Cells and Reveals Their Distinct Role during Intramuscular Immunization

(2012) C. Langlet et al.   JOURNAL OF IMMUNOLOGY

Programming the magnitude and persistence of antibody responses with innate immunity

(2011) Sudhir Pai Kasturi et al.   NATURE

Toll-like Receptor 7 Controls the Anti-Retroviral Germinal Center Response

(2011) Edward P. Browne   PLoS Pathogens

Toll-like receptor (TLR) expression on CD4+ and CD8+ T-cells in patients chronically infected with hepatitis C virus

(2010) Talia Hammond et al.   CELLULAR IMMUNOLOGY

Flagellin as an Adjuvant: Cellular Mechanisms and Potential

(2010) S. B. Mizel et al.   JOURNAL OF IMMUNOLOGY

Phenotype and function of neonatal DC

(2009) Fabienne Willems et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Plasma cell toll-like receptor (TLR) expression differs from that of B cells, and plasma cell TLR triggering enhances immunoglobulin production

(2009) Marcus Dorner et al.   IMMUNOLOGY

Toll-like receptors - sentries in the B-cell response

(2009) Isabelle Bekeredjian-Ding et al.   IMMUNOLOGY

Direct Stimulation of tlr5+/+ CD11c+ Cells Is Necessary for the Adjuvant Activity of Flagellin

(2009) J. T. Bates et al.   JOURNAL OF IMMUNOLOGY

Neonatal immunity: faulty T-helpers and the shortcomings of dendritic cells

(2009) Habib Zaghouani et al.   TRENDS IN IMMUNOLOGY

Comparison of human B cell activation by TLR7 and TLR9 agonists

(2008) John A Hanten et al.   BMC IMMUNOLOGY

Mucosal adjuvant activity of flagellin in aged mice

(2008) John T. Bates et al.   MECHANISMS OF AGEING AND DEVELOPMENT