Innate defense regulator IDR-1018 activates human mast cells through G protein-, phospholipase C-, MAPK- and NF-ĸB-sensitive pathways

The role of human β-defensins in allergic diseases

(2016) F. Niyonsaba et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Antimicrobial peptides and wound healing: biological and therapeutic considerations

(2016) Maria Luisa Mangoni et al.   EXPERIMENTAL DERMATOLOGY

Angiogenic peptide (AG)-30/5C activates human keratinocytes to produce cytokines/chemokines and to migrate and proliferate via MrgX receptors

(2016) Chanisa Kiatsurayanon et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Peptide IDR-1002 Inhibits NF-κB Nuclear Translocation by Inhibition of IκBα Degradation and Activates p38/ERK1/2–MSK1-Dependent CREB Phosphorylation in Macrophages Stimulated with Lipopolysaccharide

(2016) Alejandro Huante-Mendoza et al.   Frontiers in Immunology

Anti-infective peptide IDR-1002 augments monocyte chemotaxis towards CCR5 chemokines

(2015) Laurence Madera et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

High throughput screening methods for assessing antibiofilm and immunomodulatory activities of synthetic peptides

(2015) Evan F. Haney et al.   PEPTIDES

Metalloproteinases and Wound Healing

(2015) Matthew P. Caley et al.   Advances in Wound Care

Treatment with LL-37 is safe and effective in enhancing healing of hard-to-heal venous leg ulcers: a randomized, placebo-controlled clinical trial

(2014) Alvar Grönberg et al.   WOUND REPAIR AND REGENERATION

Innate defense regulator peptide 1018 protects against perinatal brain injury

(2013) Hayde Bolouri et al.   ANNALS OF NEUROLOGY

Mast cell activity in the healing wound: more than meets the eye?

(2013) Brian C. Wulff et al.   EXPERIMENTAL DERMATOLOGY

 -Defensins Activate Human Mast Cells via Mas-Related Gene X2

(2013) H. Subramanian et al.   JOURNAL OF IMMUNOLOGY

The innate defense regulator peptides IDR-HH2, IDR-1002, and IDR-1018 modulate human neutrophil functions

(2013) François Niyonsaba et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Pleurocidin, a novel antimicrobial peptide, induces human mast cell activation through the FPRL1 receptor

(2013) P Pundir et al.   Mucosal Immunology

Synthetic Cationic Peptide IDR-1018 Modulates Human Macrophage Differentiation

(2013) Olga M. Pena et al.   PLoS One

Monocyte chemotactic protein 3 is a homing factor for circulating angiogenic cells

(2012) Mélanie Bousquenaud et al.   CARDIOVASCULAR RESEARCH

Widespread Immunological Functions of Mast Cells: Fact or Fiction?

(2012) Hans-Reimer Rodewald et al.   IMMUNITY

Synthetic Immunomodulatory Peptide IDR-1002 Enhances Monocyte Migration and Adhesion on Fibronectin

(2012) Laurence Madera et al.   Journal of Innate Immunity

Molecular mechanisms of spontaneous and directed mast cell motility

(2012) Jinmin Lee et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Modulating immunity as a therapy for bacterial infections

(2012) Robert E. W. Hancock et al.   NATURE REVIEWS MICROBIOLOGY

Innate Defense Regulator Peptide 1018 in Wound Healing and Wound Infection

(2012) Lars Steinstraesser et al.   PLoS One

Mast Cells and Wound Healing

(2012) Carole A. Oskeritzian   Advances in Wound Care

Multifunctional cationic host defence peptides and their clinical applications

(2011) Amy T. Y. Yeung et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Catestatin, a neuroendocrine antimicrobial peptide, induces human mast cell migration, degranulation and production of cytokines and chemokines

(2011) Gyi Aung et al.   IMMUNOLOGY

Mas-related Gene X2 (MrgX2) Is a Novel G Protein-coupled Receptor for the Antimicrobial Peptide LL-37 in Human Mast Cells

(2011) Hariharan Subramanian et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Modulation of interleukin-1β-induced inflammatory responses by a synthetic cationic innate defence regulator peptide, IDR-1002, in synovial fibroblasts

(2011) Emily Turner-Brannen et al.   ARTHRITIS RESEARCH & THERAPY

Mast cells as cellular sensors in inflammation and immunity

(2011) Walid Beghdadi   Frontiers in Immunology

Structural Studies of a Peptide with Immune Modulating and Direct Antimicrobial Activity

(2010) Michal Wieczorek et al.   CHEMISTRY & BIOLOGY

The role of G protein-coupled receptors in mast cell activation by antimicrobial peptides: is there a connection?

(2010) Priyanka Pundir et al.   IMMUNOLOGY AND CELL BIOLOGY

Synthetic Cationic Peptide IDR-1002 Provides Protection against Bacterial Infections through Chemokine Induction and Enhanced Leukocyte Recruitment

(2010) Anastasia Nijnik et al.   JOURNAL OF IMMUNOLOGY

Antimicrobial Peptides Human  -Defensins and Cathelicidin LL-37 Induce the Secretion of a Pruritogenic Cytokine IL-31 by Human Mast Cells

(2010) F. Niyonsaba et al.   JOURNAL OF IMMUNOLOGY

Mast Cell Degranulation is Essential for Anastomotic Healing in Well Perfused and Poorly Perfused Rat Colon

(2010) John Coneely et al.   JOURNAL OF SURGICAL RESEARCH

Multifunctional Antimicrobial Proteins and Peptides: Natural Activators of Immune Systems

(2009) Francois Niyonsaba et al.   CURRENT PHARMACEUTICAL DESIGN

Susceptibility to Infectious Diseases Based on Antimicrobial Peptide Production

(2009) B. Rivas-Santiago et al.   INFECTION AND IMMUNITY

Human beta-defensin-3 promotes wound healing in infected diabetic wounds

(2009) Tobias Hirsch et al.   JOURNAL OF GENE MEDICINE

Advances in mast cell biology: new understanding of heterogeneity and function

(2009) T C Moon et al.   Mucosal Immunology

Potential of immunomodulatory host defense peptides as novel anti-infectives

(2009) Donna M. Easton et al.   TRENDS IN BIOTECHNOLOGY

The development of allergic inflammation

(2008) Stephen J. Galli et al.   NATURE

PERSPECTIVE ARTICLE: Growth factors and cytokines in wound healing

(2008) Stephan Barrientos et al.   WOUND REPAIR AND REGENERATION