Peptide IDR-1002 Inhibits NF-κB Nuclear Translocation by Inhibition of IκBα Degradation and Activates p38/ERK1/2–MSK1-Dependent CREB Phosphorylation in Macrophages Stimulated with Lipopolysaccharide

A Cytoplasmic NF-κB Interacting Long Noncoding RNA Blocks IκB Phosphorylation and Suppresses Breast Cancer Metastasis

(2015) Bodu Liu et al.   CANCER CELL

CREB phosphorylation at Ser133regulates transcription via distinct mechanisms downstream of cAMP and MAPK signalling

(2014) Shaista Naqvi et al.   BIOCHEMICAL JOURNAL

IL-10: The Master Regulator of Immunity to Infection

(2014) Kevin N. Couper et al.   JOURNAL OF IMMUNOLOGY

Resolution of inflammation: an integrated view

(2013) Almudena Ortega-Gómez et al.   EMBO Molecular Medicine

The innate defense regulator peptides IDR-HH2, IDR-1002, and IDR-1018 modulate human neutrophil functions

(2013) François Niyonsaba et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Human cathelicidin LL-37-derived peptide IG-19 confers protection in a murine model of collagen-induced arthritis

(2013) Leola N.Y. Chow et al.   MOLECULAR IMMUNOLOGY

Genistein Suppresses LPS-Induced Inflammatory Response through Inhibiting NF-κB following AMP Kinase Activation in RAW 264.7 Macrophages

(2013) Guiyuan Ji et al.   PLoS One

Synthetic Immunomodulatory Peptide IDR-1002 Enhances Monocyte Migration and Adhesion on Fibronectin

(2012) Laurence Madera et al.   Journal of Innate Immunity

Innate Defense Regulator Peptide 1018 in Wound Healing and Wound Infection

(2012) Lars Steinstraesser et al.   PLoS One

Regulation and Functions of the IL-10 Family of Cytokines in Inflammation and Disease

(2011) Wenjun Ouyang et al.   Annual Review of Immunology

Modulation of interleukin-1β-induced inflammatory responses by a synthetic cationic innate defence regulator peptide, IDR-1002, in synovial fibroblasts

(2011) Emily Turner-Brannen et al.   ARTHRITIS RESEARCH & THERAPY

Crosstalk of reactive oxygen species and NF-κB signaling

(2010) Michael J Morgan et al.   CELL RESEARCH

Glycogen synthase kinase 3: A point of convergence for the host inflammatory response

(2010) Huizhi Wang et al.   CYTOKINE

TLR-signaling Networks

(2010) J. Brown et al.   JOURNAL OF DENTAL RESEARCH

Synthetic Cationic Peptide IDR-1002 Provides Protection against Bacterial Infections through Chemokine Induction and Enhanced Leukocyte Recruitment

(2010) Anastasia Nijnik et al.   JOURNAL OF IMMUNOLOGY

Modulation of TNFα, IL-10 and IL-12p40 levels by a ceramide-1-phosphate analog, PCERA-1, in vivo and ex vivo in primary macrophages

(2009) Dorit Avni et al.   IMMUNOLOGY LETTERS

Anti-inflammatory Effects of Madecassic Acid via the Suppression of NF-κB Pathway in LPS-Induced RAW 264.7 Macrophage Cells

(2009) Jong-Heon Won et al.   PLANTA MEDICA

Potential of immunomodulatory host defense peptides as novel anti-infectives

(2009) Donna M. Easton et al.   TRENDS IN BIOTECHNOLOGY

Innate and adaptive immune responses regulated by glycogen synthase kinase-3 (GSK3)

(2009) Eléonore Beurel et al.   TRENDS IN IMMUNOLOGY

Shared Principles in NF-κB Signaling

(2008) Matthew S. Hayden et al.   CELL

Origin and physiological roles of inflammation

(2008) Ruslan Medzhitov   NATURE

The kinases MSK1 and MSK2 act as negative regulators of Toll-like receptor signaling

(2008) Olga Ananieva et al.   NATURE IMMUNOLOGY

Inhibition of LPS-induced NO and PGE2 production by asiatic acid via NF-κB inactivation in RAW 264.7 macrophages: Possible involvement of the IKK and MAPK pathways

(2007) Kyung-Jin Yun et al.   INTERNATIONAL IMMUNOPHARMACOLOGY