Zebrafish Models of Human Disease: Gaining Insight into Human Disease at ZFIN

Transcriptome analysis reveals a ribosome constituents disorder involved in the RPL5 downregulated zebrafish model of Diamond-Blackfan anemia

(2016) Yang Wan et al.   BMC Medical Genomics

Indomethacin treatment prior to pentylenetetrazole-induced seizures downregulates the expression of il1b and cox2 and decreases seizure-like behavior in zebrafish larvae

(2016) Patrícia Gonçalves Barbalho et al.   BMC NEUROSCIENCE

Zebrafish small molecule screens: Taking the phenotypic plunge

(2016) Charles H. Williams et al.   Computational and Structural Biotechnology Journal

A High-Content Larval Zebrafish Brain Imaging Method for Small Molecule Drug Discovery

(2016) Harrison Liu et al.   PLoS One

Impairment of social behaviour persists two years after embryonic alcohol exposure in zebrafish: A model of fetal alcohol spectrum disorders

(2015) Yohaan Fernandes et al.   BEHAVIOURAL BRAIN RESEARCH

Analysis of crosstalk between retinoic acid and sonic hedgehog pathways following ethanol exposure in embryonic zebrafish

(2015) Chengjin Zhang et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

RAP-011 improves erythropoiesis in zebrafish model of Diamond-Blackfan anemia through antagonizing lefty1

(2015) J. Ear et al.   BLOOD

Cross-species oncogenomics using zebrafish models of cancer

(2015) Richard M White   CURRENT OPINION IN GENETICS & DEVELOPMENT

Cross-organism analysis using InterMine

(2015) Rachel Lyne et al.   GENESIS

ZFIN, The zebrafish model organism database: Updates and new directions

(2015) Leyla Ruzicka et al.   GENESIS

Use of Model Organism and Disease Databases to Support Matchmaking for Human Disease Gene Discovery

(2015) Christopher J. Mungall et al.   HUMAN MUTATION

Mecp2 regulates neural cell differentiation by suppressing the Id1 to Her2 axis in zebrafish

(2015) H. Gao et al.   JOURNAL OF CELL SCIENCE

Bioactive C21 Steroidal Glycosides from the Roots of Cynanchum otophyllum That Suppress the Seizure-like Locomotor Activity of Zebrafish Caused by Pentylenetetrazole

(2015) Jin-Long Li et al.   JOURNAL OF NATURAL PRODUCTS

The Disease Ontology: fostering interoperability between biological and clinical human disease-related data

(2015) Lynn M. Schriml et al.   MAMMALIAN GENOME

Long-term behavioral impairment following acute embryonic ethanol exposure in zebrafish

(2015) J.M. Bailey et al.   NEUROTOXICOLOGY AND TERATOLOGY

A TALEN-Exon Skipping Design for a Bethlem Myopathy Model in Zebrafish

(2015) Zlatko Radev et al.   PLoS One

Role of Adenosine Signaling on Pentylenetetrazole-Induced Seizures in Zebrafish

(2015) Anna Maria Siebel et al.   Zebrafish

Analysis of crosstalk between retinoic acid and sonic hedgehog pathways following ethanol exposure in embryonic zebrafish

(2015) Chengjin Zhang et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Immobilization of Dystrophin and Laminin α2-Chain Deficient Zebrafish Larvae In Vivo Prevents the Development of Muscular Dystrophy

(2015) Mei Li et al.   PLoS One

Zebrafish models in translational research: tipping the scales toward advancements in human health

(2014) J. B. Phillips et al.   Disease Models & Mechanisms

The role of the DNA damage response in zebrafish and cellular models of Diamond Blackfan anemia

(2014) N. Danilova et al.   Disease Models & Mechanisms

Influenza A virus infection in zebrafish recapitulates mammalian infection and sensitivity to anti-influenza drug treatment

(2014) Kristin A. Gabor et al.   Disease Models & Mechanisms

Molecular and morphological changes in zebrafish following transient ethanol exposure during defined developmental stages

(2014) Chengjin Zhang et al.   NEUROTOXICOLOGY AND TERATOLOGY

Overexpression of Endothelin 1 Triggers Hepatocarcinogenesis in Zebrafish and Promotes Cell Proliferation and Migration through the AKT Pathway

(2014) Jeng-Wei Lu et al.   PLoS One

Whole Organism High Content Screening Identifies Stimulators of Pancreatic Beta-Cell Proliferation

(2014) Naoki Tsuji et al.   PLoS One

Effects of 6-Hydroxydopamine Exposure on Motor Activity and Biochemical Expression in Zebrafish (Danio Rerio) Larvae

(2014) Chien-Wei Feng et al.   Zebrafish

Defects of protein production in erythroid cells revealed in a zebrafish Diamond–Blackfan anemia model for mutation in RPS19

(2014) Y Zhang et al.   Cell Death & Disease

Altered Behavioral Performance and Live Imaging of Circuit-Specific Neural Deficiencies in a Zebrafish Model for Psychomotor Retardation

(2014) David Zada et al.   PLoS Genetics

Assessment of hematopoietic failure due to Rpl11 deficiency in a zebrafish model of Diamond-Blackfan anemia by deep sequencing

(2013) Zhaojun Zhang et al.   BMC GENOMICS

A large-scale zebrafish gene knockout resource for the genome-wide study of gene function

(2013) G. K. Varshney et al.   GENOME RESEARCH

A systematic genome-wide analysis of zebrafish protein-coding gene function

(2013) Ross N. W. Kettleborough et al.   NATURE

The zebrafish reference genome sequence and its relationship to the human genome

(2013) Kerstin Howe et al.   NATURE

Efficient genome editing in zebrafish using a CRISPR-Cas system

(2013) Woong Y Hwang et al.   NATURE BIOTECHNOLOGY

Transcriptome Analysis of the Zebrafish Model of Diamond-Blackfan Anemia from RPS19 Deficiency via p53-Dependent and -Independent Pathways

(2013) Qiong Jia et al.   PLoS One

The genetic heterogeneity and mutational burden of engineered melanomas in zebrafish models

(2013) Jennifer Yen et al.   GENOME BIOLOGY

Zebrafish screen identifies novel compound with selective toxicity against leukemia

(2012) S. Ridges et al.   BLOOD

Targeted mutagenesis of zebrafish: Use of zinc finger nucleases

(2011) Ivone Un San Leong et al.   BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS

NUP98-HOXA9-transgenic zebrafish develop a myeloproliferative neoplasm and provide new insight into mechanisms of myeloid leukaemogenesis

(2011) A. Michael Forrester et al.   BRITISH JOURNAL OF HAEMATOLOGY

Ethanolic Extract of Fructus Alpinia oxyphylla Protects Against 6-Hydroxydopamine-Induced Damage of PC12 Cells In Vitro and Dopaminergic Neurons in Zebrafish

(2011) Zai-Jun Zhang et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Heritable gene targeting in zebrafish using customized TALENs

(2011) Peng Huang et al.   NATURE BIOTECHNOLOGY

Targeted gene disruption in somatic zebrafish cells using engineered TALENs

(2011) Jeffry D Sander et al.   NATURE BIOTECHNOLOGY

Loss of Zebrafish lgi1b Leads to Hydrocephalus and Sensitization to Pentylenetetrazol Induced Seizure-Like Behavior

(2011) Yong Teng et al.   PLoS One

Parkinson's disease: Insights from non-traditional model organisms

(2010) Ilse S. Pienaar et al.   PROGRESS IN NEUROBIOLOGY

Copy Number Variation in Human Health, Disease, and Evolution

(2009) Feng Zhang et al.   Annual Review of Genomics and Human Genetics

Novel congenital myopathy locus identified in Native American Indians at 12q13.13-14.1

(2008) D. S. Stamm et al.   NEUROLOGY