Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate

Sequencing the GRHL3 Coding Region Reveals Rare Truncating Mutations and a Common Susceptibility Variant for Nonsyndromic Cleft Palate

(2016) Elisabeth Mangold et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A Genome-wide Association Study of Nonsyndromic Cleft Palate Identifies an Etiologic Missense Variant in GRHL3

(2016) Elizabeth J. Leslie et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A multi-ethnic genome-wide association study identifies novel loci for non-syndromic cleft lip with or without cleft palate on 2p24.2, 17q23 and 19q13

(2016) Elizabeth J. Leslie et al.   HUMAN MOLECULAR GENETICS

Meta-analysis Reveals Genome-Wide Significance at 15q13 for Nonsyndromic Clefting of Both the Lip and the Palate, and Functional Analyses Implicate GREM1 As a Plausible Causative Gene

(2016) Kerstin U. Ludwig et al.   PLoS Genetics

Identification of Functional Variants for Cleft Lip with or without Cleft Palate in or near PAX7, FGFR2, and NOG by Targeted Sequencing of GWAS Loci

(2015) Elizabeth J. Leslie et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Replication of 13q31.1 association in nonsyndromic cleft lip with cleft palate in Europeans

(2015) Zhonglin Jia et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

A single nucleotide polymorphism associated with isolated cleft lip and palate, thyroid cancer and hypothyroidism alters the activity of an oral epithelium and thyroid enhancer near FOXE1

(2015) Andrew C. Lidral et al.   HUMAN MOLECULAR GENETICS

HaploReg v4: systematic mining of putative causal variants, cell types, regulators and target genes for human complex traits and disease

(2015) Lucas D. Ward et al.   NUCLEIC ACIDS RESEARCH

A composite enhancer regulates p63 gene expression in epidermal morphogenesis and in keratinocyte differentiation by multiple mechanisms

(2015) Dario Antonini et al.   NUCLEIC ACIDS RESEARCH

Genome-wide association study identifies a new susceptibility locus for cleft lip with or without a cleft palate

(2015) Yimin Sun et al.   Nature Communications

Genome-Wide Association Studies in Dogs and Humans Identify ADAMTS20 as a Risk Variant for Cleft Lip and Palate

(2015) Zena T. Wolf et al.   PLoS Genetics

A novel RIPK4–IRF6 connection is required to prevent epithelial fusions characteristic for popliteal pterygium syndromes

(2014) P De Groote et al.   CELL DEATH AND DIFFERENTIATION

Interferon regulatory factor 6 regulates keratinocyte migration

(2014) L. C. Biggs et al.   JOURNAL OF CELL SCIENCE

Strong Association of Variants around FOXE1 and Orofacial Clefting

(2014) K.U. Ludwig et al.   JOURNAL OF DENTAL RESEARCH

Genetics of cleft lip and cleft palate

(2013) Elizabeth J. Leslie et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS

Confirming genes influencing risk to cleft lip with/without cleft palate in a case–parent trio study

(2013) T. H. Beaty et al.   HUMAN GENETICS

Fine Tuning of Craniofacial Morphology by Distant-Acting Enhancers

(2013) C. Attanasio et al.   SCIENCE

Expression and mutation analyses implicate ARHGAP29 as the etiologic gene for the cleft lip with or without cleft palate locus identified by genome-wide association on chromosome 1p22

(2012) Elizabeth J. Leslie et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

GWAS reveals new recessive loci associated with non-syndromic facial clefting

(2012) Mauricio Camargo et al.   European Journal of Medical Genetics

Examining Markers in 8q24 to Explain Differences in Evidence for Association With Cleft Lip With/Without Cleft Palate Between Asians and Europeans

(2012) Tanda Murray et al.   GENETIC EPIDEMIOLOGY

Genome-wide meta-analyses of nonsyndromic cleft lip with or without cleft palate identify six new risk loci

(2012) Kerstin U Ludwig et al.   NATURE GENETICS

Neural tube defects-disorders of neurulation and related embryonic processes

(2012) Andrew J. Copp et al.   Wiley Interdisciplinary Reviews-Developmental Biology

Tfap2a and Foxd3 regulate early steps in the development of the neural crest progenitor population

(2011) Wen-Der Wang et al.   DEVELOPMENTAL BIOLOGY

Evidence for gene-environment interaction in a genome wide study of nonsyndromic cleft palate

(2011) Terri H. Beaty et al.   GENETIC EPIDEMIOLOGY

Cleft lip and palate: understanding genetic and environmental influences

(2011) Michael J. Dixon et al.   NATURE REVIEWS GENETICS

HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants

(2011) L. D. Ward et al.   NUCLEIC ACIDS RESEARCH

Epidermal Wound Repair Is Regulated by the Planar Cell Polarity Signaling Pathway

(2010) Jacinta Caddy et al.   DEVELOPMENTAL CELL

A genome-wide association study of cleft lip with and without cleft palate identifies risk variants near MAFB and ABCA4

(2010) Terri H Beaty et al.   NATURE GENETICS

Genome Scan, Fine-Mapping, and Candidate Gene Analysis of Non-Syndromic Cleft Lip with or without Cleft Palate Reveals Phenotype-Specific Differences in Linkage and Association Results

(2009) Mary L. Marazita et al.   HUMAN HEREDITY

FOXE1 association with both isolated cleft lip with or without cleft palate, and isolated cleft palate

(2009) Lina M. Moreno et al.   HUMAN MOLECULAR GENETICS

A Genome-Wide Association Study Identifies a Locus for Nonsyndromic Cleft Lip with or without Cleft Palate on 8q24

(2009) Struan F.A. Grant et al.   JOURNAL OF PEDIATRICS

Genome-wide association study identifies two susceptibility loci for nonsyndromic cleft lip with or without cleft palate

(2009) Elisabeth Mangold et al.   NATURE GENETICS

Key susceptibility locus for nonsyndromic cleft lip with or without cleft palate on chromosome 8q24

(2009) Stefanie Birnbaum et al.   NATURE GENETICS

ToppGene Suite for gene list enrichment analysis and candidate gene prioritization

(2009) J. Chen et al.   NUCLEIC ACIDS RESEARCH

Disruption of an AP-2α binding site in an IRF6 enhancer is associated with cleft lip

(2008) Fedik Rahimov et al.   NATURE GENETICS