Cleft lip and palate: understanding genetic and environmental influences

AXIS inhibition protein 2, orofacial clefts and a family history of cancer

(2014) Renato Menezes et al.   JOURNAL OF THE AMERICAN DENTAL ASSOCIATION

Maternal Alcohol Consumption, Alcohol Metabolism Genes, and the Risk of Oral Clefts: A Population-based Case-Control Study in Norway, 1996-2001

(2010) A. L. Boyles et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Revisiting the recurrence risk of nonsyndromic cleft lip with or without cleft palate

(2010) Cherise M. Klotz et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Association between genetic variants of reported candidate genes or regions and risk of cleft lip with or without cleft palate in the polish population

(2010) Adrianna Mostowska et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

The etiology of cleft palate: a 50-year search for mechanistic and molecular understanding

(2010) Barbara D. Abbott   BIRTH DEFECTS RESEARCH PART B-DEVELOPMENTAL AND REPRODUCTIVE TOXICOLOGY

Association between TGFB3 and Nonsyndromic Cleft Lip with or Without Cleft Palate in a Chilean Population

(2010) José Suazo et al.   CLEFT PALATE-CRANIOFACIAL JOURNAL

Cerebellum Structure Differences and Relationship to Speech in Boys and Girls with Nonsyndromic Cleft of the Lip and/or Palate

(2010) Amy L. Conrad et al.   CLEFT PALATE-CRANIOFACIAL JOURNAL

Ethnic Heterogeneity of IRF6 AP-2a Binding Site Promoter SNP Association with Nonsyndromic Cleft Lip and Palate

(2010) Susan H. Blanton et al.   CLEFT PALATE-CRANIOFACIAL JOURNAL

MTHFR and MSX1 contribute to the risk of nonsyndromic cleft lip/palate

(2010) Triin Jagomägi et al.   EUROPEAN JOURNAL OF ORAL SCIENCES

The gene, environment association studies consortium (GENEVA): maximizing the knowledge obtained from GWAS by collaboration across studies of multiple conditions

(2010) Marilyn C. Cornelis et al.   GENETIC EPIDEMIOLOGY

Evidence of gene–environment interaction for the IRF6 gene and maternal multivitamin supplementation in controlling the risk of cleft lip with/without cleft palate

(2010) Tao Wu et al.   HUMAN GENETICS

Cooperation between the transcription factors p63 and IRF6 is essential to prevent cleft palate in mice

(2010) Helen A. Thomason et al.   JOURNAL OF CLINICAL INVESTIGATION

Wound Complications After Cleft Repair in Children With Van der Woude Syndrome

(2010) Jodi L.P. Jones et al.   JOURNAL OF CRANIOFACIAL SURGERY

A genome-wide association study of cleft lip with and without cleft palate identifies risk variants near MAFB and ABCA4

(2010) Terri H Beaty et al.   NATURE GENETICS

Exome sequencing identifies MLL2 mutations as a cause of Kabuki syndrome

(2010) Sarah B Ng et al.   NATURE GENETICS

Valproic Acid Monotherapy in Pregnancy and Major Congenital Malformations

(2010) Janneke Jentink et al.   NEW ENGLAND JOURNAL OF MEDICINE

Whole-Genome Sequencing in a Patient with Charcot–Marie–Tooth Neuropathy

(2010) James R. Lupski et al.   NEW ENGLAND JOURNAL OF MEDICINE

Autoantibodies to Folate Receptor α During Early Pregnancy and Risk of Oral Clefts in Denmark

(2010) Camilla Bille et al.   PEDIATRIC RESEARCH

Analysis of Genetic Inheritance in a Family Quartet by Whole-Genome Sequencing

(2010) J. C. Roach et al.   SCIENCE

Rare Variants Create Synthetic Genome-Wide Associations

(2010) Samuel P. Dickson et al.   PLOS BIOLOGY

Mutations in BMP4 Are Associated with Subepithelial, Microform, and Overt Cleft Lip

(2009) Satoshi Suzuki et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Whorl patterns on the lower lip are associated with nonsyndromic cleft lip with or without cleft palate

(2009) Katherine Neiswanger et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Orofacial clefts in the National Birth Defects Prevention Study, 1997-2004

(2009) Alicia E. Genisca et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Identification of microdeletions in candidate genes for cleft lip and/or palate

(2009) Min Shi et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Importance of gene-environment interactions in the etiology of selected birth defects

(2009) H Zhu et al.   CLINICAL GENETICS

Lrp6-mediated canonical Wnt signaling is required for lip formation and fusion

(2009) L. Song et al.   DEVELOPMENT

Association Among Polymorphisms at MYH9, Environmental Factors, and Nonsyndromic Orofacial Clefts in Western China

(2009) Zhong-Lin Jia et al.   DNA AND CELL BIOLOGY

Mutation Analysis of the PVRL1 Gene in Caucasians with Nonsyndromic Cleft Lip/Palate

(2009) Mehmet A. Sözen et al.   Genetic Testing and Molecular Biomarkers

Genome Scan, Fine-Mapping, and Candidate Gene Analysis of Non-Syndromic Cleft Lip with or without Cleft Palate Reveals Phenotype-Specific Differences in Linkage and Association Results

(2009) Mary L. Marazita et al.   HUMAN HEREDITY

Tbx22 null mice have a submucous cleft palate due to reduced palatal bone formation and also display ankyloglossia and choanal atresia phenotypes

(2009) Erwin Pauws et al.   HUMAN MOLECULAR GENETICS

Integration of IRF6 and Jagged2 signalling is essential for controlling palatal adhesion and fusion competence

(2009) Rebecca J. Richardson et al.   HUMAN MOLECULAR GENETICS

FOXE1 association with both isolated cleft lip with or without cleft palate, and isolated cleft palate

(2009) Lina M. Moreno et al.   HUMAN MOLECULAR GENETICS

Analysis of interactions between genetic variants of BMP4 and environmental factors with nonsyndromic cleft lip with or without cleft palate susceptibility

(2009) L. Jianyan et al.   INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY

A cohort study of recurrence patterns among more than 54 000 relatives of oral cleft cases in Denmark: support for the multifactorial threshold model of inheritance

(2009) D. Grosen et al.   JOURNAL OF MEDICAL GENETICS

A Genome-Wide Association Study Identifies a Locus for Nonsyndromic Cleft Lip with or without Cleft Palate on 8q24

(2009) Struan F.A. Grant et al.   JOURNAL OF PEDIATRICS

Cleft lip and palate

(2009) Peter A Mossey et al.   LANCET

Genomic views of distant-acting enhancers

(2009) Axel Visel et al.   NATURE

Exome sequencing identifies the cause of a mendelian disorder

(2009) Sarah B Ng et al.   NATURE GENETICS

Genome-wide association study identifies two susceptibility loci for nonsyndromic cleft lip with or without cleft palate

(2009) Elisabeth Mangold et al.   NATURE GENETICS

Key susceptibility locus for nonsyndromic cleft lip with or without cleft palate on chromosome 8q24

(2009) Stefanie Birnbaum et al.   NATURE GENETICS

The genetics of isolated orofacial clefts: from genotypes to subphenotypes

(2009) A Jugessur et al.   ORAL DISEASES

The impact of orofacial clefts on quality of life and healthcare use and costs

(2009) GL Wehby et al.   ORAL DISEASES

Folic acid and orofacial clefts: a review of the evidence

(2009) GL Wehby et al.   ORAL DISEASES

Face shape of unaffected parents with cleft affected offspring: combining three-dimensional surface imaging and geometric morphometrics

(2009) SM Weinberg et al.   Orthodontics & Craniofacial Research

A New Computational Tool for the Phenomenological Analysis of Multipassage Tumor Growth Curves

(2009) Antonio S. Gliozzi et al.   PLoS One

First-Trimester Maternal Alcohol Consumption and the Risk of Infant Oral Clefts in Norway: A Population-based Case-Control Study

(2008) L. A. DeRoo et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

TFAP2A Mutations Result in Branchio-Oculo-Facial Syndrome

(2008) Jeff M. Milunsky et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Rethinking isolated cleft palate: Evidence of occult lip defects in a subset of cases

(2008) Seth M. Weinberg et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Three-dimensional morphometric analysis of craniofacial shape in the unaffected relatives of individuals with nonsyndromic orofacial clefts: A possible marker for genetic susceptibility

(2008) Seth M. Weinberg et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Folate-related gene polymorphisms as risk factors for cleft lip and cleft palate

(2008) James L. Mills et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Plasma zinc concentrations of mothers and the risk of oral clefts in their children in Utah

(2008) Ronald G. Munger et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Review on genetic variants and maternal smoking in the etiology of oral clefts and other birth defects

(2008) Min Shi et al.   BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS

Anatomical Basis for Apparent Subepithelial Cleft Lip: A Histological and Ultrasonographic Survey of the Orbicularis Oris Muscle

(2008) Carolyn R. Rogers et al.   CLEFT PALATE-CRANIOFACIAL JOURNAL

The PDGF-C regulatory region SNP rs28999109 decreases promoter transcriptional activity and is associated with CL/P

(2008) Sun J Choi et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Genomic screening identifies novel linkages and provides further evidence for a role of MYH9 in nonsyndromic cleft lip and palate

(2008) Brett T Chiquet et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Candidate gene/loci studies in cleft lip/palate and dental anomalies finds novel susceptibility genes for clefts

(2008) Alexandre R Vieira et al.   GENETICS IN MEDICINE

Variation in WNT genes is associated with non-syndromic cleft lip with or without cleft palate

(2008) Brett T. Chiquet et al.   HUMAN MOLECULAR GENETICS

Folate intake, markers of folate status and oral clefts: is the evidence converging?

(2008) C. Y Johnson et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Disruption of an AP-2α binding site in an IRF6 enhancer is associated with cleft lip

(2008) Fedik Rahimov et al.   NATURE GENETICS

MicroRNA Mirn140 modulates Pdgf signaling during palatogenesis

(2008) Johann K Eberhart et al.   NATURE GENETICS

Ultraconservation identifies a small subset of extremely constrained developmental enhancers

(2008) Axel Visel et al.   NATURE GENETICS

‘Mendelian randomization’ equals instrumental variable analysis with genetic instruments

(2008) George L. Wehby et al.   STATISTICS IN MEDICINE