The histone methyltransferase Suv39h2 contributes to nonalcoholic steatohepatitis in mice

Angiogenic factor with G patch and FHA domains 1 (Aggf1) regulates liver fibrosis by modulating TGF-β signaling

(2016) Bisheng Zhou et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Diet, weight loss, and liver health in nonalcoholic fatty liver disease: Pathophysiology, evidence, and practice

(2016) Giulio Marchesini et al.   HEPATOLOGY

Myocardin-related transcription factor A (MRTF-A) plays an essential role in hepatic stellate cell activation by epigenetically modulating TGF-β signaling

(2016) Wenfang Tian et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

H3K9me3 Inhibition Improves Memory, Promotes Spine Formation, and Increases BDNF Levels in the Aged Hippocampus

(2016) S. Snigdha et al.   JOURNAL OF NEUROSCIENCE

MKL1 is an epigenetic modulator of TGF-β induced fibrogenesis

(2015) Zhiwen Fan et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

MicroRNA-223 is a crucial mediator of PPARγ-regulated alternative macrophage activation

(2015) Wei Ying et al.   JOURNAL OF CLINICAL INVESTIGATION

Epigenetics: The genome unwrapped

(2015) Heidi Ledford   NATURE

SUV39H2 methylates and stabilizes LSD1 by inhibiting polyubiquitination in human cancer cells

(2015) Lianhua Piao et al.   Oncotarget

The Adipocyte-Inducible Secreted Phospholipases PLA2G5 and PLA2G2E Play Distinct Roles in Obesity

(2014) Hiroyasu Sato et al.   Cell Metabolism

Endogenous annexin A1 is a novel protective determinant in nonalcoholic steatohepatitis in mice

(2014) Irene Locatelli et al.   HEPATOLOGY

Regulation of Lipogenic Gene Expression by Lysine-specific Histone Demethylase-1 (LSD1)

(2014) Arian Abdulla et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MRTF-A mediates LPS-induced pro-inflammatory transcription by interacting with the COMPASS complex

(2014) L. Yu et al.   JOURNAL OF CELL SCIENCE

Suv39h1 Mediates AP-2 -Dependent Inhibition of C/EBP  Expression during Adipogenesis

(2014) Z.-C. Zhang et al.   MOLECULAR AND CELLULAR BIOLOGY

Non-histone protein methylation as a regulator of cellular signalling and function

(2014) Kyle K. Biggar et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Myeloid Deletion of SIRT1 Aggravates Serum Transfer Arthritis in Mice via Nuclear Factor-κB Activation

(2014) Young-Sool Hah et al.   PLoS One

Transforming growth factor beta signaling in hepatocytes participates in steatohepatitis through regulation of cell death and lipid metabolism in mice

(2013) Ling Yang et al.   HEPATOLOGY

Decoding cell death signals in liver inflammation

(2013) Catherine Brenner et al.   JOURNAL OF HEPATOLOGY

Suppression of Gluconeogenic Gene Expression by LSD1-Mediated Histone Demethylation

(2013) Dongning Pan et al.   PLoS One

Lysine-specific demethylase 1 (LSD1) and histone deacetylase 1 (HDAC1) synergistically repress proinflammatory cytokines and classical complement pathway components

(2012) Andreas Janzer et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

NASH is an Infl ammatory Disorder: Pathogenic, Prognostic and Therapeutic Implications

(2012) Geoffrey C. Farrell et al.   Gut and Liver

Brahma-related gene 1 bridges epigenetic regulation of proinflammatory cytokine production to steatohepatitis in mice

(2012) Wenfang Tian et al.   HEPATOLOGY

Docosahexaenoic acid ameliorates palmitate-induced lipid accumulation and inflammation through repressing NLRC4 inflammasome activation in HepG2 cells

(2012) Xiaoqin Luo et al.   Nutrition & Metabolism

Acute stress and hippocampal histone H3 lysine 9 trimethylation, a retrotransposon silencing response

(2012) R. G. Hunter et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PPARs at the crossroads of lipid signaling and inflammation

(2012) Walter Wahli et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Genetic Examination of SETD7 and SUV39H1/H2 Methyltransferases and the Risk of Diabetes Complications in Patients With Type 1 Diabetes

(2011) Anna Syreeni et al.   DIABETES

Fatty acid and endotoxin activate inflammasomes in mouse hepatocytes that release danger signals to stimulate immune cells

(2011) Timea Csak et al.   HEPATOLOGY

Epigenetic Regulation of Surfactant Protein A Gene (SP-A) Expression in Fetal Lung Reveals a Critical Role for Suv39h Methyltransferases during Development and Hypoxia

(2011) H. Benlhabib et al.   MOLECULAR AND CELLULAR BIOLOGY

Antihepatoma activity of chaetocin due to deregulated splicing of hypoxia-inducible factor 1α pre-mRNA in mice and in vitro

(2010) Yoon-Mi Lee et al.   HEPATOLOGY

Nonalcoholic fatty liver disease and hepatocellular carcinoma: A weighty connection

(2010) Brad Q. Starley et al.   HEPATOLOGY

High-fructose, medium chain trans fat diet induces liver fibrosis and elevates plasma coenzyme Q9 in a novel murine model of obesity and nonalcoholic steatohepatitis

(2010) Rohit Kohli et al.   HEPATOLOGY

Evolution of inflammation in nonalcoholic fatty liver disease: The multiple parallel hits hypothesis

(2010) Herbert Tilg et al.   HEPATOLOGY

PPAR control: it's SIRTainly as easy as PGC

(2009) Mary C Sugden et al.   JOURNAL OF ENDOCRINOLOGY

Epidemiology of non-alcoholic fatty liver disease in China

(2008) Jian-Gao Fan et al.   JOURNAL OF HEPATOLOGY

Origin and physiological roles of inflammation

(2008) Ruslan Medzhitov   NATURE