Genetic dissection of oligodendroglial and neuronal Plp1 function in a novel mouse model of spastic paraplegia type 2

The balance between cathepsin C and cystatin F controls remyelination in the brain of Plp1 -overexpressing mouse, a chronic demyelinating disease model

(2017) Takahiro Shimizu et al.   GLIA

Astrocytic Orosomucoid-2 Modulates Microglial Activation and Neuroinflammation

(2017) Myungjin Jo et al.   JOURNAL OF NEUROSCIENCE

Neurotoxic reactive astrocytes are induced by activated microglia

(2017) Shane A. Liddelow et al.   NATURE

Antagonistic Functions of MBP and CNP Establish Cytosolic Channels in CNS Myelin

(2017) Nicolas Snaidero et al.   Cell Reports

Monitoring ATP dynamics in electrically active white matter tracts

(2017) Andrea Trevisiol et al.   eLife

The immunomodulatory oligodendrocyte

(2016) Thomas Zeis et al.   BRAIN RESEARCH

Electron microscopy of myelin: Structure preservation by high-pressure freezing

(2016) Wiebke Möbius et al.   BRAIN RESEARCH

Pathogenicinflammation in the CNS of mice carrying humanPLP1mutations

(2016) Janos Groh et al.   HUMAN MOLECULAR GENETICS

Proteolipid protein–deficient myelin promotes axonal mitochondrial dysfunction via altered metabolic coupling

(2016) Xinghua Yin et al.   JOURNAL OF CELL BIOLOGY

Is involvement of inflammation underestimated in Pelizaeus-Merzbacher disease?

(2016) Antoine Marteyn et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Down Syndrome Developmental Brain Transcriptome Reveals Defective Oligodendrocyte Differentiation and Myelination

(2016) Jose Luis Olmos-Serrano et al.   NEURON

Microglia and brain macrophages: An update

(2016) Atsushi Sasaki   NEUROPATHOLOGY

Concise Review: Stem Cell-Based Treatment of Pelizaeus-Merzbacher Disease

(2016) M. Joana Osorio et al.   STEM CELLS

Septin/anillin filaments scaffold central nervous system myelin to accelerate nerve conduction

(2016) Julia Patzig et al.   eLife

Proteolipid protein modulates preservation of peripheral axons and premature death when myelin protein zero is lacking

(2015) Julia Patzig et al.   GLIA

Myelin Proteolipid Protein Complexes with  v Integrin and AMPA Receptors In Vivo and Regulates AMPA-Dependent Oligodendrocyte Progenitor Cell Migration through the Modulation of Cell-Surface GluR2 Expression

(2015) D. E. Harlow et al.   JOURNAL OF NEUROSCIENCE

Innate and adaptive immune responses in the CNS

(2015) Ari Waisman et al.   LANCET NEUROLOGY

Case definition and classification of leukodystrophies and leukoencephalopathies

(2015) Adeline Vanderver et al.   MOLECULAR GENETICS AND METABOLISM

Modeling the natural history of Pelizaeus–Merzbacher disease

(2015) Joshua A. Mayer et al.   NEUROBIOLOGY OF DISEASE

Cell types in the mouse cortex and hippocampus revealed by single-cell RNA-seq

(2015) A. Zeisel et al.   SCIENCE

Modulation of the Innate Immune Response by Human Neural Precursors Prevails over Oligodendrocyte Progenitor Remyelination to Rescue a Severe Model of Pelizaeus-Merzbacher Disease

(2015) Antoine Marteyn et al.   STEM CELLS

Progesterone Antagonist Therapy in a Pelizaeus-Merzbacher Mouse Model

(2014) Thomas Prukop et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Myelination of the Nervous System: Mechanisms and Functions

(2014) Klaus-Armin Nave et al.   Annual Review of Cell and Developmental Biology

T-cell-mediated regulation of neuroinflammation involved in neurodegenerative diseases

(2014) Hugo González et al.   Journal of Neuroinflammation

An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex

(2014) Y. Zhang et al.   JOURNAL OF NEUROSCIENCE

Mice with a deletion of the major central myelin protein exhibit hypersensitivity to noxious thermal stimuli: involvement of central sensitization

(2014) Bérengère Petit et al.   NEUROBIOLOGY OF DISEASE

Hereditary spastic paraplegia: clinico-pathologic features and emerging molecular mechanisms

(2013) John K. Fink   ACTA NEUROPATHOLOGICA

Molecular evolution of myelin basic protein, an abundant structural myelin component

(2013) Schanila Nawaz et al.   GLIA

Uncoupling of neuroinflammation from axonal degeneration in mice lacking the myelin protein tetraspanin-2

(2013) Patricia de Monasterio-Schrader et al.   GLIA

A critical role for the cholesterol-associated proteolipids PLP and M6B in myelination of the central nervous system

(2013) Hauke B. Werner et al.   GLIA

Oligodendrocyte Lineage Cells Contribute Unique Features to Rett Syndrome Neuropathology

(2013) M. V. C. Nguyen et al.   JOURNAL OF NEUROSCIENCE

Neuronal Basic Helix-Loop-Helix Proteins Neurod2/6 Regulate Cortical Commissure Formation before Midline Interactions

(2013) I. Bormuth et al.   JOURNAL OF NEUROSCIENCE

Degeneration and impaired regeneration of gray matter oligodendrocytes in amyotrophic lateral sclerosis

(2013) Shin H Kang et al.   NATURE NEUROSCIENCE

The Ventral Hippocampus Is the Embryonic Origin for Adult Neural Stem Cells in the Dentate Gyrus

(2013) Guangnan Li et al.   NEURON

Loss of electrostatic cell-surface repulsion mediates myelin membrane adhesion and compaction in the central nervous system

(2013) M. Bakhti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neurotransmitter-Triggered Transfer of Exosomes Mediates Oligodendrocyte–Neuron Communication

(2013) Carsten Frühbeis et al.   PLOS BIOLOGY

Astrocytes regulate myelin clearance through recruitment of microglia during cuprizone-induced demyelination

(2012) Thomas Skripuletz et al.   BRAIN

Systematic approaches to central nervous system myelin

(2012) Patricia de Monasterio-Schrader et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

A myelin gene causative of a catatonia-depression syndrome upon aging

(2012) Nora Hagemeyer et al.   EMBO Molecular Medicine

Innate immunity in the central nervous system

(2012) Richard M. Ransohoff et al.   JOURNAL OF CLINICAL INVESTIGATION

Effect of curcumin in a mouse model of Pelizaeus–Merzbacher disease

(2012) Li-Hua Yu et al.   MOLECULAR GENETICS AND METABOLISM

Oligodendroglia metabolically support axons and contribute to neurodegeneration

(2012) Youngjin Lee et al.   NATURE

Glycolytic oligodendrocytes maintain myelin and long-term axonal integrity

(2012) Ursula Fünfschilling et al.   NATURE

Therapy of Pelizaeus-Merzbacher disease in mice by feeding a cholesterol-enriched diet

(2012) Gesine Saher et al.   NATURE MEDICINE

Neuroinflammation by Cytotoxic T-Lymphocytes Impairs Retrograde Axonal Transport in an Oligodendrocyte Mutant Mouse

(2012) Chi Wang Ip et al.   PLoS One

Neural Stem Cell Engraftment and Myelination in the Human Brain

(2012) N. Gupta et al.   Science Translational Medicine

Developmental Activation of the Proteolipid Protein Promoter Transgene in Neuronal and Oligodendroglial Cells of Neostriatum in Mice

(2011) Daniel Fulton et al.   DEVELOPMENTAL NEUROSCIENCE

Axon-glial interaction in the CNS: what we have learned from mouse models of Pelizaeus-Merzbacher disease

(2011) Fredrik I. Gruenenfelder et al.   JOURNAL OF ANATOMY

The Proteolipid Protein Promoter Drives Expression outside of the Oligodendrocyte Lineage during Embryonic and Early Postnatal Development

(2011) John-Paul Michalski et al.   PLoS One

Demyelination and axonal preservation in a transgenic mouse model of Pelizaeus-Merzbacher disease

(2010) Julia M. Edgar et al.   EMBO Molecular Medicine

Myelination and the trophic support of long axons

(2010) Klaus-Armin Nave   NATURE REVIEWS NEUROSCIENCE

Early ultrastructural defects of axons and axon-glia junctions in mice lacking expression ofCnp1

(2009) Julia M. Edgar et al.   GLIA

Mice with Altered Myelin Proteolipid Protein Gene Expression Display Cognitive Deficits Accompanied by Abnormal Neuron-Glia Interactions and Decreased Conduction Velocities

(2009) H. Tanaka et al.   JOURNAL OF NEUROSCIENCE

Neuronal expression of the proteolipid protein gene in the medulla of the mouse

(2009) Martha J. Miller et al.   JOURNAL OF NEUROSCIENCE RESEARCH

The SNARE protein SNAP-29 interacts with the GTPase Rab3A: Implications for membrane trafficking in myelinating glia

(2009) Anke Schardt et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Myelin Proteomics: Molecular Anatomy of an Insulating Sheath

(2009) Olaf Jahn et al.   MOLECULAR NEUROBIOLOGY

Phylogeny of proteolipid proteins: divergence, constraints, and the evolution of novel functions in myelination and neuroprotection

(2009) Wiebke Möbius et al.   Neuron Glia Biology

Novel neuronal proteolipid protein isoforms encoded by the human myelin proteolipid protein 1 gene

(2009) C. Sarret et al.   NEUROSCIENCE

Mutation in the myelin proteolipid protein gene alters BK and SK channel function in the caudal medulla

(2009) Catherine A. Mayer et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Application of a Translational Profiling Approach for the Comparative Analysis of CNS Cell Types

(2008) Joseph P. Doyle et al.   CELL

The molecular and cellular defects underlying Pelizaeus–Merzbacher disease

(2008) Karen J. Woodward   EXPERT REVIEWS IN MOLECULAR MEDICINE

Separate Proteolipid Protein/DM20 Enhancers Serve Different Lineages and Stages of Development

(2008) M. C. Tuason et al.   JOURNAL OF NEUROSCIENCE

Neuregulin-1/ErbB Signaling Serves Distinct Functions in Myelination of the Peripheral and Central Nervous System

(2008) Bastian G. Brinkmann et al.   NEURON

THREE-DIMENSIONAL MICROSURGICAL AND TRACTOGRAPHIC ANATOMY OF THE WHITE MATTER OF THE HUMAN BRAIN

(2008) Juan C. Fernández-Miranda et al.   NEUROSURGERY