Ancient antagonism between CELF and RBFOX families tunes mRNA splicing outcomes

Rbfox Proteins Regulate Splicing as Part of a Large Multiprotein Complex LASR

(2016) Andrey Damianov et al.   CELL

Resources for the Comprehensive Discovery of Functional RNA Elements

(2016) Balaji Sundararaman et al.   MOLECULAR CELL

RNA Sequence Context Effects Measured In Vitro Predict In Vivo Protein Binding and Regulation

(2016) J. Matthew Taliaferro et al.   MOLECULAR CELL

Robust transcriptome-wide discovery of RNA-binding protein binding sites with enhanced CLIP (eCLIP)

(2016) Eric L Van Nostrand et al.   NATURE METHODS

Cytoplasmic Rbfox1 Regulates the Expression of Synaptic and Autism-Related Genes

(2016) Ji-Ann Lee et al.   NEURON

Identification of Targets of CUG-BP, Elav-Like Family Member 1 (CELF1) Regulation in Embryonic Heart Muscle

(2016) Yotam Blech-Hermoni et al.   PLoS One

Position-dependent activity of CELF2 in the regulation of splicing and implications for signal-responsive regulation in T cells

(2016) Sandya Ajith et al.   RNA Biology

Dysregulation of RBFOX2 Is an Early Event in Cardiac Pathogenesis of Diabetes

(2016) Curtis A. Nutter et al.   Cell Reports

Enhanced CLIP Uncovers IMP Protein-RNA Targets in Human Pluripotent Stem Cells Important for Cell Adhesion and Survival

(2016) Anne E. Conway et al.   Cell Reports

Developmental regulation of RNA processing by Rbfox proteins

(2016) John G. Conboy   Wiley Interdisciplinary Reviews-RNA

Widespread JNK-dependent alternative splicing induces a positive feedback loop through CELF2-mediated regulation of MKK7 during T-cell activation

(2015) Nicole M. Martinez et al.   GENES & DEVELOPMENT

Antagonistic regulation of mRNA expression and splicing by CELF and MBNL proteins

(2015) Eric T. Wang et al.   GENOME RESEARCH

The RNA-binding protein Rbfox1 regulates splicing required for skeletal muscle structure and function

(2015) Simona Pedrotti et al.   HUMAN MOLECULAR GENETICS

Induced transcription and stability of CELF2 mRNA drives widespread alternative splicing during T-cell signaling

(2015) Michael J. Mallory et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Repression of the Central Splicing Regulator RBFox2 Is Functionally Linked to Pressure Overload-Induced Heart Failure

(2015) Chaoliang Wei et al.   Cell Reports

The RNA-binding protein Arrest (Bruno) regulates alternative splicing to enable myofibril maturation in Drosophila flight muscle

(2014) M. L. Spletter et al.   EMBO REPORTS

RBFOX and PTBP1 proteins regulate the alternative splicing of micro-exons in human brain transcripts

(2014) Yang I. Li et al.   GENOME RESEARCH

Rbfox2-Coordinated Alternative Splicing of Mef2d and Rock2 Controls Myoblast Fusion during Myogenesis

(2014) Ravi K. Singh et al.   MOLECULAR CELL

RNA Bind-n-Seq: Quantitative Assessment of the Sequence and Structural Binding Specificity of RNA Binding Proteins

(2014) Nicole Lambert et al.   MOLECULAR CELL

A Pair of RNA-Binding Proteins Controls Networks of Splicing Events Contributing to Specialization of Neural Cell Types

(2014) Adam D. Norris et al.   MOLECULAR CELL

Context-dependent control of alternative splicing by RNA-binding proteins

(2014) Xiang-Dong Fu et al.   NATURE REVIEWS GENETICS

RBFOX1 Cooperates with MBNL1 to Control Splicing in Muscle, Including Events Altered in Myotonic Dystrophy Type 1

(2014) Roscoe Klinck et al.   PLoS One

Tissue-specific splicing of a ubiquitously expressed transcription factor is essential for muscle differentiation

(2013) S. Sebastian et al.   GENES & DEVELOPMENT

Reactivation of Fetal Splicing Programs in Diabetic Hearts Is Mediated by Protein Kinase C Signaling

(2013) Sunil K. Verma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Position-dependent and neuron-specific splicing regulation by the CELF family RNA-binding protein UNC-75 in Caenorhabditis elegans

(2013) Hidehito Kuroyanagi et al.   NUCLEIC ACIDS RESEARCH

MBNL1 and RBFOX2 cooperate to establish a splicing programme involved in pluripotent stem cell differentiation

(2013) Julian P. Venables et al.   Nature Communications

AVISPA: a web tool for the prediction and analysis of alternative splicing

(2013) Yoseph Barash et al.   GENOME BIOLOGY

The splicing regulator Rbfox2 is required for both cerebellar development and mature motor function

(2012) L. T. Gehman et al.   GENES & DEVELOPMENT

Genome-Wide Determination of a Broad ESRP-Regulated Posttranscriptional Network by High-Throughput Sequencing

(2012) K. A. Dittmar et al.   MOLECULAR AND CELLULAR BIOLOGY

Integrative Genome-wide Analysis Reveals Cooperative Regulation of Alternative Splicing by hnRNP Proteins

(2012) Stephanie C. Huelga et al.   Cell Reports

Muscle-Specific Splicing Factors ASD-2 and SUP-12 Cooperatively Switch Alternative Pre-mRNA Processing Patterns of the ADF/Cofilin Gene in Caenorhabditis elegans

(2012) Genta Ohno et al.   PLoS Genetics

CELF4 Regulates Translation and Local Abundance of a Vast Set of mRNAs, Including Genes Associated with Regulation of Synaptic Function

(2012) Jacy L. Wagnon et al.   PLoS Genetics

An integrative approach to ortholog prediction for disease-focused and other functional studies

(2011) Yanhui Hu et al.   BMC BIOINFORMATICS

Rbfox-regulated alternative splicing is critical for zebrafish cardiac and skeletal muscle functions

(2011) Thomas L. Gallagher et al.   DEVELOPMENTAL BIOLOGY

Signal- and Development-Dependent Alternative Splicing of LEF1 in T Cells Is Controlled by CELF2

(2011) M. J. Mallory et al.   MOLECULAR AND CELLULAR BIOLOGY

Functional consequences of developmentally regulated alternative splicing

(2011) Auinash Kalsotra et al.   NATURE REVIEWS GENETICS

MicroRNAs coordinate an alternative splicing network during mouse postnatal heart development

(2010) A. Kalsotra et al.   GENES & DEVELOPMENT

Differential expression analysis for sequence count data

(2010) Simon Anders et al.   GENOME BIOLOGY

Transcriptional induction and translational inhibition of Arc and Cugbp2 in mice hippocampus after transient global ischemia under normothermic condition

(2009) Noboru Otsuka et al.   BRAIN RESEARCH

RNA and Disease

(2009) Thomas A. Cooper et al.   CELL

Forcing cells to change lineages

(2009) Thomas Graf et al.   NATURE

An RNA code for the FOX2 splicing regulator revealed by mapping RNA-protein interactions in stem cells

(2009) Gene W Yeo et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Autoregulation of Fox protein expression to produce dominant negative splicing factors

(2009) A. Damianov et al.   RNA

The CUGBP2 Splicing Factor Regulates an Ensemble of Branchpoints from Perimeter Binding Sites with Implications for Autoregulation

(2009) Jill A. Dembowski et al.   PLoS Genetics

Defining the regulatory network of the tissue-specific splicing factors Fox-1 and Fox-2

(2008) C. Zhang et al.   GENES & DEVELOPMENT

Properties of developmental gene regulatory networks

(2008) E. H. Davidson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A postnatal switch of CELF and MBNL proteins reprograms alternative splicing in the developing heart

(2008) A. Kalsotra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA