Modulation of heme oxygenase-1 expression and activity affects streptozotocin-induced diabetic nephropathy in rats

Role of Nrf2/HO-1 system in development, oxidative stress response and diseases: an evolutionarily conserved mechanism

(2016) Agnieszka Loboda et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Mechanistic insight of diabetic nephropathy and its pharmacotherapeutic targets: An update

(2016) Niloy Bhattacharjee et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Geniposide reduces development of streptozotocin-induced diabetic nephropathy via regulating nuclear factor-kappa B signaling pathways

(2016) Xiaolei Hu et al.   FUNDAMENTAL & CLINICAL PHARMACOLOGY

Momordica charantia polysaccharides mitigate the progression of STZ induced diabetic nephropathy in rats

(2016) Mohammad Raish et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Targeting HO-1 by Epigallocatechin-3-Gallate Reduces Contrast-Induced Renal Injury via Anti-Oxidative Stress and Anti-Inflammation Pathways

(2016) Zhao Gao et al.   PLoS One

Induction of heme oxygenase-1 with hemin alleviates cisplatin-induced reproductive toxicity in male rats and enhances its cytotoxicity in prostate cancer cell line

(2016) Gehan Hussein Heeba et al.   TOXICOLOGY LETTERS

Oxidative Stress in Diabetic Nephropathy with Early Chronic Kidney Disease

(2016) Alejandra Guillermina Miranda-Díaz et al.   Journal of Diabetes Research

Penehyclidine Hydrochloride Pretreatment Ameliorates Rhabdomyolysis-Induced AKI by Activating the Nrf2/HO-1 Pathway and Allevi-ating Endoplasmic Reticulum Stress in Rats

(2016) Wei Zhao et al.   PLoS One

HO-1 expression control in the rat glomerulus

(2015) Maria G. Detsika et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

PKCε-CREB-Nrf2 signalling induces HO-1 in the vascular endothelium and enhances resistance to inflammation and apoptosis

(2015) Hayley Mylroie et al.   CARDIOVASCULAR RESEARCH

Polydatin promotes Nrf2-ARE anti-oxidative pathway through activating Sirt1 to resist AGEs-induced upregulation of fibronetin and transforming growth factor-β1 in rat glomerular messangial cells

(2015) Kaipeng Huang et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Heme oxygenase-1, a novel target for the treatment of diabetic complications: focus on diabetic peripheral neuropathy

(2015) Geeta Negi et al.   PHARMACOLOGICAL RESEARCH

Calorie restriction mimicking effects of roflumilast prevents diabetic nephropathy

(2014) Kulbhushan Tikoo et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Heme oxygenase-1 alleviates vascular complications associated with metabolic syndrome: Effect on endothelial dependent relaxation and NO production

(2014) Hany M. El-Bassossy et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Hemin Improves Insulin Sensitivity in Skeletal Muscle in High Fat–Fed Mice

(2014) Tae-Jin Ju et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

The Heme Oxygenase System Suppresses Perirenal Visceral Adiposity, Abates Renal Inflammation and Ameliorates Diabetic Nephropathy in Zucker Diabetic Fatty Rats

(2014) Joseph Fomusi Ndisang et al.   PLoS One

The Use of Functional Chemical-Protein Associations to Identify Multi-Pathway Renoprotectants

(2014) Jia Xu et al.   PLoS One

Novel Faces of Heme Oxygenase-1: Mechanisms and Therapeutic Potentials

(2013) Jozef Dulak et al.   ANTIOXIDANTS & REDOX SIGNALING

Length Polymorphism in Heme Oxygenase-1 and Cardiovascular Events and Mortality in Hemodialysis Patients

(2013) Y.-H. Chen et al.   Clinical Journal of the American Society of Nephrology

Hemin Therapy Improves Kidney Function in Male Streptozotocin-Induced Diabetic Rats: Role of the Heme Oxygenase/Atrial Natriuretic Peptide/Adiponectin Axis

(2013) Joseph Fomusi Ndisang et al.   ENDOCRINOLOGY

Lectin-like oxidized low-density lipoprotein receptor 1 pathways

(2013) Ashraf Taye et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Activation of renal haeme oxygenase-1 alleviates gentamicin-induced acute nephrotoxicity in rats

(2013) Ashraf Taye et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Heme oxygenase-1 induction protects against hypertension associated with diabetes: effect on exaggerated vascular contractility

(2013) N. Hassan et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

The Heme Oxygenase System Rescues Hepatic Deterioration in the Condition of Obesity Co-Morbid with Type-2 Diabetes

(2013) Tatiana Ntube Salley et al.   PLoS One

Heme Oxygenase 1 Modulates Thrombomodulin and Endothelial Protein C Receptor Levels to Attenuate Septic Kidney Injury

(2013) Kai Kang et al.   SHOCK

Heme oxygenase 1 improves glucoses metabolism and kidney histological alterations in diabetic rats

(2013) Ellen ON Ptilovanciv et al.   Diabetology & Metabolic Syndrome

Role of Heme Oxygenase-1 in Polymyxin B-Induced Nephrotoxicity in Rats

(2012) Cassiane Dezoti Fonseca et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Inhibition of high glucose-induced inflammatory response and macrophage infiltration by a novel curcumin derivative prevents renal injury in diabetic rats

(2012) Yong Pan et al.   BRITISH JOURNAL OF PHARMACOLOGY

Insulin receptor and IRS-1 co-immunoprecipitation with SOCS-3, and IKKα/β phosphorylation are increased in obese Zucker rat skeletal muscle

(2012) Ilya A. Zolotnik et al.   LIFE SCIENCES

Attenuation of Glomerular Injury in Diabetic Mice with Tert-Butylhydroquinone through Nuclear Factor Erythroid 2-Related Factor 2-Dependent Antioxidant Gene Activation

(2011) Hang Li et al.   AMERICAN JOURNAL OF NEPHROLOGY

Effect of heme oxygenase-1 on renal function in rats with liver cirrhosis

(2011) Shi-Bin Guo   WORLD JOURNAL OF GASTROENTEROLOGY

Nrf2, a Guardian of Healthspan and Gatekeeper of Species Longevity

(2010) K. N. Lewis et al.   INTEGRATIVE AND COMPARATIVE BIOLOGY

The Heme Oxygenase-1 Genotype is a Risk Factor to Renal Impairment of IgA Nephropathy at Diagnosis, Which is a Strong Predictor of Mortality

(2009) Ho Jun Chin et al.   JOURNAL OF KOREAN MEDICAL SCIENCE

Induction of heme oxygenase-1 protects against podocyte apoptosis under diabetic conditions

(2009) Sang Choel Lee et al.   KIDNEY INTERNATIONAL