Dynamics behind affinity maturation of an anti-HCMV antibody family influencing antigen binding

Cytomegalovirus Vaccines: Current Status and Future Prospects

(2016) K. M. Anderholm et al.   DRUGS

Structures of Preferred Human IgV Genes–Based Protective Antibodies Identify How Conserved Residues Contact Diverse Antigens and Assign Source of Specificity to CDR3 Loop Variation

(2016) Steve Bryson et al.   JOURNAL OF IMMUNOLOGY

Preclinical evaluations of peptide-conjugate vaccines targeting the antigenic domain-2 of glycoprotein B of human cytomegalovirus

(2016) Adam C. Finnefrock et al.   Human Vaccines & Immunotherapeutics

Key mutations stabilize antigen-binding conformation during affinity maturation of a broadly neutralizing influenza antibody lineage

(2015) Huafeng Xu et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Rigidity Emerges during Antibody Evolution in Three Distinct Antibody Systems: Evidence from QSFR Analysis of Fab Fragments

(2015) Tong Li et al.   PLoS Computational Biology

Large-scale analysis of somatic hypermutations in antibodies reveals which structural regions, positions and amino acids are modified to improve affinity

(2013) Anat Burkovitz et al.   FEBS Journal

The immune response to human CMV

(2012) Corinna La Rosa et al.   Future Virology

Affinity-based selection and the germinal center response

(2012) Tyani D. Chan et al.   IMMUNOLOGICAL REVIEWS

Preconfiguration of the antigen-binding site during affinity maturation of a broadly neutralizing influenza virus antibody

(2012) A. G. Schmidt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The association of heavy and light chain variable domains in antibodies: implications for antigen specificity

(2011) Anna Chailyan et al.   FEBS Journal

Cytomegalovirus: pathogen, paradigm, and puzzle

(2011) Michael Boeckh et al.   JOURNAL OF CLINICAL INVESTIGATION

Effects of somatic mutations on CDR loop flexibility during affinity maturation

(2010) Sergio E. Wong et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Optimized Molecular Dynamics Force Fields Applied to the Helix−Coil Transition of Polypeptides

(2009) Robert B. Best et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Germline V-genes sculpt the binding site of a family of antibodies neutralizing human cytomegalovirus

(2008) Christy A Thomson et al.   EMBO JOURNAL

Determination of Alkali and Halide Monovalent Ion Parameters for Use in Explicitly Solvated Biomolecular Simulations

(2008) In Suk Joung et al.   JOURNAL OF PHYSICAL CHEMISTRY B