The membrane activity of BOK involves formation of large, stable toroidal pores and is promoted by cBID

BOK Is a Non-canonical BCL-2 Family Effector of Apoptosis Regulated by ER-Associated Degradation

(2016) Fabien Llambi et al.   CELL

Cardiolipin or MTCH2 can serve as tBID receptors during apoptosis

(2016) E Raemy et al.   CELL DEATH AND DIFFERENTIATION

Bax assembly into rings and arcs in apoptotic mitochondria is linked to membrane pores

(2016) R. Salvador-Gallego et al.   EMBO JOURNAL

The Stability and Expression Level of Bok Are Governed by Binding to Inositol 1,4,5-Trisphosphate Receptors

(2016) Jacqualyn J. Schulman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bok is a genuine multi-BH-domain protein that triggers apoptosis in the absence of Bax and Bak

(2016) Stephanie Einsele-Scholz et al.   JOURNAL OF CELL SCIENCE

Bok Is Not Pro-Apoptotic But Suppresses Poly ADP-Ribose Polymerase-Dependent Cell Death Pathways and Protects against Excitotoxic and Seizure-Induced Neuronal Injury

(2016) B. D'Orsi et al.   JOURNAL OF NEUROSCIENCE

Is BOK required for apoptosis induced by endoplasmic reticulum stress?

(2016) Yuniel Fernandez-Marrero et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

cBid, Bax and Bcl-xL exhibit opposite membrane remodeling activities

(2016) S Bleicken et al.   Cell Death & Disease

Distinct lipid effects on tBid and Bim activation of membrane permeabilization by pro-apoptotic Bax

(2015) Aisha Shamas-Din et al.   BIOCHEMICAL JOURNAL

Membrane curvature at a glance

(2015) H. T. McMahon et al.   JOURNAL OF CELL SCIENCE

BCL-2 family member BOK promotes apoptosis in response to endoplasmic reticulum stress

(2015) Marcos A. Carpio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Impact of the combined loss of BOK, BAX and BAK on the hematopoietic system is slightly more severe than compound loss of BAX and BAK

(2015) F Ke et al.   Cell Death & Disease

Bax monomers form dimer units in the membrane that further self-assemble into multiple oligomeric species

(2015) Yamunadevi Subburaj et al.   Nature Communications

Heat stress induced apoptosis is triggered by transcription-independent p53, Ca2+ dyshomeostasis and the subsequent Bax mitochondrial translocation

(2015) Z. T. Gu et al.   Scientific Reports

Automated analysis of giant unilamellar vesicles using circular Hough transformation

(2014) Eduard Hermann et al.   BIOINFORMATICS

Mechanistic Differences in the Membrane Activity of Bax and Bcl-xL Correlate with Their Opposing Roles in Apoptosis

(2013) Stephanie Bleicken et al.   BIOPHYSICAL JOURNAL

Intracellular localization of the BCL-2 family member BOK and functional implications

(2013) N Echeverry et al.   CELL DEATH AND DIFFERENTIATION

Involvement of cardiolipin in tBID-induced activation of BAX during apoptosis

(2013) Etienne Raemy et al.   CHEMISTRY AND PHYSICS OF LIPIDS

The Bcl-2 Protein Family Member Bok Binds to the Coupling Domain of Inositol 1,4,5-Trisphosphate Receptors and Protects Them from Proteolytic Cleavage

(2013) Jacqualyn J. Schulman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proapoptotic Bax and Bak Proteins Form Stable Protein-permeable Pores of Tunable Size

(2013) Stephanie Bleicken et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Consequences of the combined loss of BOK and BAK or BOK and BAX

(2013) F Ke et al.   Cell Death & Disease

Sphingolipid Metabolism Cooperates with BAK and BAX to Promote the Mitochondrial Pathway of Apoptosis

(2012) Jerry E. Chipuk et al.   CELL

BH3-only proteins are tail-anchored in the outer mitochondrial membrane and can initiate the activation of Bax

(2012) F Wilfling et al.   CELL DEATH AND DIFFERENTIATION

BCL-2 family member BOK is widely expressed but its loss has only minimal impact in mice

(2012) F Ke et al.   CELL DEATH AND DIFFERENTIATION

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Reconstitution of Proapoptotic BAK Function in Liposomes Reveals a Dual Role for Mitochondrial Lipids in the BAK-driven Membrane Permeabilization Process

(2011) Olatz Landeta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A unified method for purification of basic proteins

(2010) Sanjay Adhikari et al.   ANALYTICAL BIOCHEMISTRY

The vesicle-to-micelle transformation of phospholipid–cholate mixed aggregates: A state of the art analysis including membrane curvature effects

(2010) Mustafa M.A. Elsayed et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Mtd/Bok takes a swing: proapoptotic Mtd/Bok regulates trophoblast cell proliferation during human placental development and in preeclampsia

(2009) J E Ray et al.   CELL DEATH AND DIFFERENTIATION

Molecular Details of Bax Activation, Oligomerization, and Membrane Insertion

(2009) Stephanie Bleicken et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Contributions to Bax insertion and oligomerization of lipids of the mitochondrial outer membrane

(2008) S Lucken-Ardjomande et al.   CELL DEATH AND DIFFERENTIATION

The BCL-2 protein family: opposing activities that mediate cell death

(2007) Richard J. Youle et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY