Dynamic control of RSK complexes by phosphoswitch-based regulation

Regulation of the Equilibrium between Closed and Open Conformations of Annexin A2 by N-Terminal Phosphorylation and S100A4-Binding

(2017) Péter Ecsédi et al.   STRUCTURE

The dynamic subcellular localization of ERK: mechanisms of translocation and role in various organelles

(2016) Ehud Wainstein et al.   CURRENT OPINION IN CELL BIOLOGY

Sequence Determinants of the Conformational Properties of an Intrinsically Disordered Protein Prior to and upon Multisite Phosphorylation

(2016) Erik W. Martin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A molecular code for endosomal recycling of phosphorylated cargos by the SNX27–retromer complex

(2016) Thomas Clairfeuille et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A molecular code for endosomal recycling of phosphorylated cargos by the SNX27–retromer complex

(2016) Thomas Clairfeuille et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Ras-activated RSK1 phosphorylates EBP50 to regulate its nuclear localization and promote cell proliferation

(2016) HooiCheng Lim et al.   Oncotarget

Bacterial Expression, Purification and In Vitro Phosphorylation of Full-Length Ribosomal S6 Kinase 2 (RSK2)

(2016) Darkhan Utepbergenov et al.   PLoS One

NanoLuc Complementation Reporter Optimized for Accurate Measurement of Protein Interactions in Cells

(2015) Andrew S. Dixon et al.   ACS Chemical Biology

Disorder-To-Order Transition of MAGI-1 PDZ1 C-Terminal Extension upon Peptide Binding: Thermodynamic and Dynamic Insights

(2015) Juan Ramírez et al.   BIOCHEMISTRY

Structural Basis of Ribosomal S6 Kinase 1 (RSK1) Inhibition by S100B Protein

(2015) Gergő Gógl et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural assembly of the signaling competent ERK2–RSK1 heterodimeric protein kinase complex

(2015) Anita Alexa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Folding of an intrinsically disordered protein by phosphorylation as a regulatory switch

(2014) Alaji Bah et al.   NATURE

PhosphoSitePlus, 2014: mutations, PTMs and recalibrations

(2014) Peter V. Hornbeck et al.   NUCLEIC ACIDS RESEARCH

Kinetic modulation of a disordered protein domain by phosphorylation

(2014) Nathaniel Stanley et al.   Nature Communications

Protein–peptide complex crystallization: a case study on the ERK2 mitogen-activated protein kinase

(2013) Gergő Gógl et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

GROMACS 4.5: a high-throughput and highly parallel open source molecular simulation toolkit

(2013) Sander Pronk et al.   BIOINFORMATICS

Molecular basis of MAP kinase regulation

(2013) Wolfgang Peti et al.   PROTEIN SCIENCE

Motional timescale predictions by molecular dynamics simulations: Case study using proline and hydroxyproline sidechain dynamics

(2013) Abil E. Aliev et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Multisite Phosphorylation Disrupts Arginine-Glutamate Salt Bridge Networks Required for Binding of Cytoplasmic Linker-associated Protein 2 (CLASP2) to End-binding Protein 1 (EB1)

(2012) Praveen Kumar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Specificity of Linear Motifs That Bind to a Common Mitogen-Activated Protein Kinase Docking Groove

(2012) A. Garai et al.   Science Signaling

Sequence-Dependent Enrichment of a Model Phosphopeptide: A Combined MALDI-TOF and NMR Study

(2011) Lucrèce Matheron et al.   ANALYTICAL CHEMISTRY

The Structural and Dynamic Response of MAGI-1 PDZ1 with Noncanonical Domain Boundaries to the Binding of Human Papillomavirus E6

(2011) Sebastian Charbonnier et al.   JOURNAL OF MOLECULAR BIOLOGY

Activation and Function of the MAPKs and Their Substrates, the MAPK-Activated Protein Kinases

(2011) M. Cargnello et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Deficiency of Sorting Nexin 27 (SNX27) Leads to Growth Retardation and Elevated Levels of N-Methyl-D-Aspartate Receptor 2C (NR2C)

(2011) L. Cai et al.   MOLECULAR AND CELLULAR BIOLOGY

Rosetta FlexPepDock web server—high resolution modeling of peptide–protein interactions

(2011) Nir London et al.   NUCLEIC ACIDS RESEARCH

Identification of MAGI1 as a tumor-suppressor protein induced by cyclooxygenase-2 inhibitors in colorectal cancer cells

(2011) J Zaric et al.   ONCOGENE

Phosphorylation in Protein-Protein Binding: Effect on Stability and Function

(2011) Hafumi Nishi et al.   STRUCTURE

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Oscillatory dynamics of the extracellular signal-regulated kinase pathway

(2010) Harish Shankaran et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Beta-2 adrenergic receptor mediated ERK activation is regulated by interaction with MAGI-3

(2010) Xiaomei Yang et al.   FEBS LETTERS

Signalling ballet in space and time

(2010) Boris N. Kholodenko et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Additional Serine/Threonine Phosphorylation Reduces Binding Affinity but Preserves Interface Topography of Substrate Proteins to the c-Cbl TKB Domain

(2010) Qingxiang Sun et al.   PLoS One

Rapid and sustained nuclear–cytoplasmic ERK oscillations induced by epidermal growth factor

(2009) Harish Shankaran et al.   Molecular Systems Biology

The nuts and bolts of AGC protein kinases

(2009) Laura R. Pearce et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

ELM: the status of the 2010 eukaryotic linear motif resource

(2009) Cathryn M. Gould et al.   NUCLEIC ACIDS RESEARCH

FGF induces oscillations of Hes1 expression and Ras/ERK activation

(2008) Kei Nakayama et al.   CURRENT BIOLOGY

Defining the minimal interacting regions of the tight junction protein MAGI-1 and HPV16 E6 oncoprotein for solution structure studies

(2008) Sebastian Charbonnier et al.   PROTEIN EXPRESSION AND PURIFICATION

A Specificity Map for the PDZ Domain Family

(2008) Raffi Tonikian et al.   PLOS BIOLOGY