microRNA-132: a key noncoding RNA operating in the cellular phase of Alzheimer’s disease

Identification of miRNA Changes in Alzheimer's Disease Brain and CSF Yields Putative Biomarkers and Insights into Disease Pathways

(2017) John P. Cogswell et al.   JOURNAL OF ALZHEIMERS DISEASE

MicroRNA-132 and early growth response-1 in nucleus basalis of Meynert during the course of Alzheimer’s disease

(2016) Qiong-Bin Zhu et al.   BRAIN

The Cellular Phase of Alzheimer’s Disease

(2016) Bart De Strooper et al.   CELL

miR‐132 loss de‐represses ITPKB and aggravates amyloid and TAU pathology in Alzheimer's brain

(2016) Evgenia Salta et al.   EMBO Molecular Medicine

The amyloid cascade hypothesis: are we poised for success or failure?

(2016) Eric Karran et al.   JOURNAL OF NEUROCHEMISTRY

Anti-microRNAs as Novel Therapeutic Agents in the Clinical Management of Alzheimer's Disease

(2016) Yuhai Zhao et al.   Frontiers in Neuroscience

Altered Levels of MicroRNA-9, -206, and -132 in Spinal Muscular Atrophy and Their Response to Antisense Oligonucleotide Therapy

(2016) Francesco Catapano et al.   Molecular Therapy-Nucleic Acids

microRNA-132/212 deficiency enhances Aβ production and senile plaque deposition in Alzheimer’s disease triple transgenic mice

(2016) Julia Hernandez-Rapp et al.   Scientific Reports

Memory formation and retention are affected in adult miR-132/212 knockout mice

(2015) Julia Hernandez-Rapp et al.   BEHAVIOURAL BRAIN RESEARCH

Time-Dependent Profiles of MicroRNA Expression Induced by Ischemic Preconditioning in the Gerbil Hippocampus

(2015) Miao Sun et al.   CELL TRANSPLANTATION

Intranasal delivery: circumventing the iron curtain to treat neurological disorders

(2015) Yongjun Jiang et al.   Expert Opinion on Drug Delivery

Early-onset sleep defects inDrosophilamodels of Huntington's disease reflect alterations of PKA/CREB signaling

(2015) Erin D. Gonzales et al.   HUMAN MOLECULAR GENETICS

miR-132/212 deficiency impairs tau metabolism and promotes pathological aggregationin vivo

(2015) Pascal Y. Smith et al.   HUMAN MOLECULAR GENETICS

A Single miRNA-mRNA Interaction Affects the Immune Response in a Context- and Cell-Type-Specific Manner

(2015) Li-Fan Lu et al.   IMMUNITY

The Effect of miR-132, miR-146a, and miR-155 on MRP8/TLR4-Induced Astrocyte-Related Inflammation

(2015) Huimin Kong et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Neuroinflammation in Alzheimer's disease

(2015) Michael T Heneka et al.   LANCET NEUROLOGY

Immune attack: the role of inflammation in Alzheimer disease

(2015) Frank L. Heppner et al.   NATURE REVIEWS NEUROSCIENCE

CREB expression mediates amyloid β-induced basal BDNF downregulation

(2015) Elyse Rosa et al.   NEUROBIOLOGY OF AGING

Variance in the identification of microRNAs deregulated in Alzheimer's disease and possible role of lincRNAs in the pathology: The need of larger datasets

(2014) Pierre Lau et al.   AGEING RESEARCH REVIEWS

Dysregulation of Neurotrophic and Haematopoietic Growth Factors in Alzheimer’s Disease: From Pathophysiology to Novel Treatment Strategies

(2014) Kateryna Sopova et al.   Current Alzheimer Research

A Self-Organizing miR-132/Ctbp2 Circuit Regulates Bimodal Notch Signals and Glial Progenitor Fate Choice during Spinal Cord Maturation

(2014) Evgenia Salta et al.   DEVELOPMENTAL CELL

The Gene Silencing Transcription Factor REST Represses miR-132 Expression in Hippocampal Neurons Destined to Die

(2014) Jee-Yeon Hwang et al.   JOURNAL OF MOLECULAR BIOLOGY

MicroRNA-132 Is Enriched in Developing Axons, Locally Regulates Rasa1 mRNA, and Promotes Axon Extension

(2014) M. L. Hancock et al.   JOURNAL OF NEUROSCIENCE

Tumor Necrosis Factor Alpha: A Link between Neuroinflammation and Excitotoxicity

(2014) Gabriel Olmos et al.   MEDIATORS OF INFLAMMATION

Endogenous miRNA and Target Concentrations Determine Susceptibility to Potential ceRNA Competition

(2014) Andrew D. Bosson et al.   MOLECULAR CELL

REST and stress resistance in ageing and Alzheimer’s disease

(2014) Tao Lu et al.   NATURE

The Intersection of Amyloid Beta and Tau at Synapses in Alzheimer’s Disease

(2014) Tara L. Spires-Jones et al.   NEURON

MicroRNA-132 dysregulation in Toxoplasma gondii infection has implications for dopamine signaling pathway

(2014) J. Xiao et al.   NEUROSCIENCE

Using mice to model Alzheimer's dementia: an overview of the clinical disease and the preclinical behavioral changes in 10 mouse models

(2014) Scott J. Webster et al.   Frontiers in Genetics

Soluble pathological tau in the entorhinal cortex leads to presynaptic deficits in an early Alzheimer’s disease model

(2013) Manuela Polydoro et al.   ACTA NEUROPATHOLOGICA

The dendritic hypothesis for Alzheimer's disease pathophysiology

(2013) J. Nicholas Cochran et al.   BRAIN RESEARCH BULLETIN

Alteration of the microRNA network during the progression of Alzheimer's disease

(2013) Pierre Lau et al.   EMBO Molecular Medicine

miRNA expression is modulated over time after focal ischaemia: up-regulation of miR-347 promotes neuronal apoptosis

(2013) Carme Gubern et al.   FEBS Journal

In vivoknockdown of hippocampal miR-132 expression impairs memory acquisition of trace fear conditioning

(2013) Ruo-Yu Wang et al.   HIPPOCAMPUS

De-repression of FOXO3a death axis by microRNA-132 and -212 causes neuronal apoptosis in Alzheimer's disease

(2013) Hon-Kit Andus Wong et al.   HUMAN MOLECULAR GENETICS

Identification of a unique TGF-β–dependent molecular and functional signature in microglia

(2013) Oleg Butovsky et al.   NATURE NEUROSCIENCE

Global changes in DNA methylation and hydroxymethylation in Alzheimer's disease human brain

(2013) Natacha Coppieters et al.   NEUROBIOLOGY OF AGING

Dynamic expression of miR-132, miR-212, and miR-146 in the brain of different hosts infected with Angiostrongylus cantonensis

(2013) Liping Yu et al.   PARASITOLOGY RESEARCH

miR-132/212 Knockout Mice Reveal Roles for These miRNAs in Regulating Cortical Synaptic Transmission and Plasticity

(2013) Judit Remenyi et al.   PLoS One

Systemic dysregulation of TDP-43 binding microRNAs in amyotrophic lateral sclerosis

(2013) Axel Freischmidt et al.   Acta Neuropathologica Communications

miR-206 regulates brain-derived neurotrophic factor in Alzheimer disease model

(2012) Soon-Tae Lee et al.   ANNALS OF NEUROLOGY

miRNA-132: a dynamic regulator of cognitive capacity

(2012) Katelin F. Hansen et al.   Brain Structure & Function

Developing MicroRNA Therapeutics

(2012) Eva van Rooij et al.   CIRCULATION RESEARCH

Convergent repression of Foxp2 3'UTR by miR-9 and miR-132 in embryonic mouse neocortex: implications for radial migration of neurons

(2012) Y. M. Clovis et al.   DEVELOPMENT

MicroRNA-132 regulates recognition memory and synaptic plasticity in the perirhinal cortex

(2012) Helen L. Scott et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

The early contribution of cerebrovascular factors to the pathogenesis of Alzheimer’s disease

(2012) Pedro M. Pimentel-Coelho et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Influenza A Virus Infection of Human Respiratory Cells Induces Primary MicroRNA Expression

(2012) William A. Buggele et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

miR-132 regulates the differentiation of dopamine neurons by directly targeting Nurr1 expression

(2012) D. Yang et al.   JOURNAL OF CELL SCIENCE

Regulation of TLR2-Mediated Tolerance and Cross-Tolerance through IRAK4 Modulation by miR-132 and miR-212

(2012) M. A. Nahid et al.   JOURNAL OF IMMUNOLOGY

TMEM106B, the Risk Gene for Frontotemporal Dementia, Is Regulated by the microRNA-132/212 Cluster and Affects Progranulin Pathways

(2012) A. S. Chen-Plotkin et al.   JOURNAL OF NEUROSCIENCE

Non-coding RNAs with essential roles in neurodegenerative disorders

(2012) Evgenia Salta et al.   LANCET NEUROLOGY

miR-212/132 expression and functions: within and beyond the neuronal compartment

(2012) A. Wanet et al.   NUCLEIC ACIDS RESEARCH

DNA methylation silences miR-132 in prostate cancer

(2012) A Formosa et al.   ONCOGENE

miR-132 Enhances Dendritic Morphogenesis, Spine Density, Synaptic Integration, and Survival of Newborn Olfactory Bulb Neurons

(2012) Manavendra Pathania et al.   PLoS One

Early Mechanisms of Pathobiology Are Revealed by Transcriptional Temporal Dynamics in Hippocampal CA1 Neurons of Prion Infected Mice

(2012) Anna Majer et al.   PLoS Pathogens

Downregulation of miR-132 by promoter methylation contributes to pancreatic cancer development

(2011) Shuyu Zhang et al.   CARCINOGENESIS

CREB-activity and nmnat2 transcription are down-regulated prior to neurodegeneration, while NMNAT2 over-expression is neuroprotective, in a mouse model of human tauopathy

(2011) M. Cecilia Ljungberg et al.   HUMAN MOLECULAR GENETICS

MicroRNA-132 loss is associated with tau exon 10 inclusion in progressive supranuclear palsy

(2011) Pascal Y. Smith et al.   HUMAN MOLECULAR GENETICS

MicroRNA212/132 family: Molecular transducer of neuronal function and plasticity

(2011) Paola Tognini et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Neuron-Specific Effects of Interleukin-1  Are Mediated by a Novel Isoform of the IL-1 Receptor Accessory Protein

(2011) Y. Huang et al.   JOURNAL OF NEUROSCIENCE

Adult hippocampal neurogenesis and its role in Alzheimer's disease

(2011) Yangling Mu et al.   Molecular Neurodegeneration

miR-132, an experience-dependent microRNA, is essential for visual cortex plasticity

(2011) Nikolaos Mellios et al.   NATURE NEUROSCIENCE

miR-132 Mediates the Integration of Newborn Neurons into the Adult Dentate Gyrus

(2011) Bryan W. Luikart et al.   PLoS One

Toll-like receptor signaling in neural plasticity and disease

(2011) Eitan Okun et al.   TRENDS IN NEUROSCIENCES

Regulation of the miR-212/132 locus by MSK1 and CREB in response to neurotrophins

(2010) Judit Remenyi et al.   BIOCHEMICAL JOURNAL

miRNA-132 orchestrates chromatin remodeling and translational control of the circadian clock

(2010) Matías Alvarez-Saavedra et al.   HUMAN MOLECULAR GENETICS

miR-132 regulates antiviral innate immunity through suppression of the p300 transcriptional co-activator

(2010) Dimitrios Lagos et al.   NATURE CELL BIOLOGY

MicroRNA-132–mediated loss of p120RasGAP activates the endothelium to facilitate pathological angiogenesis

(2010) Sudarshan Anand et al.   NATURE MEDICINE

Regulation of Synaptic Structure and Function by FMRP-Associated MicroRNAs miR-125b and miR-132

(2010) Dieter Edbauer et al.   NEURON

microRNA-132 regulates dendritic growth and arborization of newborn neurons in the adult hippocampus

(2010) S. T. Magill et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA-132 Potentiates Cholinergic Anti-Inflammatory Signaling by Targeting Acetylcholinesterase

(2009) Iftach Shaked et al.   IMMUNITY

An activity-induced microRNA controls dendritic spine formation by regulating Rac1-PAK signaling

(2009) Soren Impey et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Gene Dysregulation in Huntington’s Disease: REST, MicroRNAs and Beyond

(2009) Rory Johnson et al.   NEUROMOLECULAR MEDICINE

Soluble Oligomers of Amyloid β Protein Facilitate Hippocampal Long-Term Depression by Disrupting Neuronal Glutamate Uptake

(2009) Shaomin Li et al.   NEURON

Glucocorticoid attenuates brain-derived neurotrophic factor-dependent upregulation of glutamate receptors via the suppression of microRNA-132 expression

(2009) H. Kawashima et al.   NEUROSCIENCE

An activity-regulated microRNA controls dendritic plasticity by down-regulating p250GAP

(2008) Gary A. Wayman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA and proteome expression profiling in early-symptomatic α-synuclein(A30P)-transgenic mice

(2008) Frank Gillardon et al.   Proteomics Clinical Applications