Anti-microRNAs as Novel Therapeutic Agents in the Clinical Management of Alzheimer's Disease

Identification of miRNA Changes in Alzheimer's Disease Brain and CSF Yields Putative Biomarkers and Insights into Disease Pathways

(2017) John P. Cogswell et al.   JOURNAL OF ALZHEIMERS DISEASE

Recent progress in microRNA delivery for cancer therapy by non-viral synthetic vectors

(2015) Huiyuan Wang et al.   ADVANCED DRUG DELIVERY REVIEWS

Alzheimer's disease first symptoms are age dependent: Evidence from the NACC dataset

(2015) Josephine Barnes et al.   Alzheimers & Dementia

Summary of the evidence on modifiable risk factors for cognitive decline and dementia: A population-based perspective

(2015) Matthew Baumgart et al.   Alzheimers & Dementia

Clinical utility of cerebrospinal fluid biomarkers in the diagnosis of early Alzheimer's disease

(2015) Kaj Blennow et al.   Alzheimers & Dementia

Exosomes: A Role for Naturally Occurring Nanovesicles in Cancer Growth, Diagnosis and Treatment

(2015) Akhil Srivastava et al.   CURRENT GENE THERAPY

Mechanisms of microRNA turnover

(2015) Maryam Sanei et al.   CURRENT OPINION IN PLANT BIOLOGY

Reactive Oxygen Species, Redox Signaling and Neuroinflammation in Alzheimer's Disease: The NF-κB Connection

(2015) Upinder Kaur et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Significance of NF-κB as a pivotal therapeutic target in the neurodegenerative pathologies of Alzheimer’s disease and multiple sclerosis

(2015) Mythily Srinivasan et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Recent developments in the nomenclature, presence, isolation, detection and clinical impact of extracellular vesicles

(2015) E. van der Pol et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

The Long, the Short, and the Unstructured: A Unifying Model of miRNA Biogenesis

(2015) Rémy Denzler et al.   MOLECULAR CELL

The Menu of Features that Define Primary MicroRNAs and Enable De Novo Design of MicroRNA Genes

(2015) Wenwen Fang et al.   MOLECULAR CELL

microRNA (miRNA)-Mediated Pathogenetic Signaling in Alzheimer’s Disease (AD)

(2015) James M. Hill et al.   NEUROCHEMICAL RESEARCH

The regulation of exosome function in the CNS: implications for neurodegeneration

(2015) F Properzi et al.   SWISS MEDICAL WEEKLY

The Whereabouts of microRNA Actions: Cytoplasm and Beyond

(2015) Anthony K.L. Leung   TRENDS IN CELL BIOLOGY

Neuroinflammation and Depression: Microglia Activation, Extracellular Microvesicles and microRNA Dysregulation

(2015) Dora Brites et al.   Frontiers in Cellular Neuroscience

Altered microRNA profiles in cerebrospinal fluid exosome in Parkinson disease and Alzheimer disease

(2015) YaXing Gui et al.   Oncotarget

Associations between Potentially Modifiable Risk Factors and Alzheimer Disease: A Mendelian Randomization Study

(2015) Søren D. Østergaard et al.   PLOS MEDICINE

Induction of the pro-inflammatory NF-kB-sensitive miRNA-146a by human neurotrophic viruses

(2015) James M. Hill et al.   Frontiers in Microbiology

Increase in NF-κB-sensitive miRNA-146a and miRNA-155 in multiple sclerosis (MS) and pro-inflammatory neurodegeneration

(2015) Deidre J. Devier et al.   Frontiers in Molecular Neuroscience

The emerging role of microRNAs in Alzheimer's disease

(2015) Grazia D. Femminella et al.   Frontiers in Physiology

Pathogenic microRNAs Common to Brain and Retinal Degeneration; Recent Observations in Alzheimer’s Disease and Age-Related Macular Degeneration

(2015) James M. Hill et al.   Frontiers in Neurology

microRNA-Based Biomarkers and the Diagnosis of Alzheimer’s Disease

(2015) Yuhai Zhao et al.   Frontiers in Neurology

Nanocarrier-mediated co-delivery of chemotherapeutic drugs and gene agents for cancer treatment

(2015) Lin Kang et al.   Acta Pharmaceutica Sinica B

Interhemispheric Functional and Structural Disconnection in Alzheimer’s Disease: A Combined Resting-State fMRI and DTI Study

(2015) Zhiqun Wang et al.   PLoS One

Deciphering the Function and Regulation of microRNAs in Alzheimer’s Disease and Parkinson’s Disease

(2014) Lifeng Qiu et al.   ACS Chemical Neuroscience

Attention and CERAD test performances in cognitively impaired elderly subjects

(2014) S. Verhülsdonk et al.   ACTA NEUROLOGICA SCANDINAVICA

Regulatory networks between neurotrophins and miRNAs in brain diseases and cancers

(2014) Jian Shi   ACTA PHARMACOLOGICA SINICA

Variance in the identification of microRNAs deregulated in Alzheimer's disease and possible role of lincRNAs in the pathology: The need of larger datasets

(2014) Pierre Lau et al.   AGEING RESEARCH REVIEWS

MicroRNA (miRNA): Sequence and stability, viroid-like properties, and disease association in the CNS

(2014) Aileen I. Pogue et al.   BRAIN RESEARCH

Single nucleotide seed modification restores in vivo tolerability of a toxic artificial miRNA sequence in the mouse brain

(2014) Alex Mas Monteys et al.   NUCLEIC ACIDS RESEARCH

Epidemiology and Etiology of Alzheimer’s disease: From Genetic to Non- Genetic Factors

(2013) Teng Jiang et al.   Current Alzheimer Research

Progress in microRNA delivery

(2013) Yu Zhang et al.   JOURNAL OF CONTROLLED RELEASE

Treatment of HCV Infection by Targeting MicroRNA

(2013) Harry L.A. Janssen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Variability in micro RNA (miRNA) abundance, speciation and complexity amongst different human populations and potential relevance to Alzheimer's disease (AD)

(2013) Walter J. Lukiw   Frontiers in Cellular Neuroscience

Studying micro RNA Function and Dysfunction in Alzheimer’s Disease

(2013) Walter J. Lukiw et al.   Frontiers in Genetics

Antagonism of NF-κB-up-regulated micro RNAs (miRNAs) in sporadic Alzheimer's disease (AD)—anti-NF-κB vs. anti-miRNA strategies

(2013) Walter J. Lukiw   Frontiers in Genetics

MicroRNAs in cerebrospinal fluid identify glioblastoma and metastatic brain cancers and reflect disease activity

(2012) N. M. Teplyuk et al.   NEURO-ONCOLOGY

NF-κB-regulated, proinflammatory miRNAs in Alzheimer's disease

(2012) Walter J Lukiw   Alzheimers Research & Therapy

Evolution and Complexity of Micro RNA in the Human Brain

(2012) Walter J. Lukiw   Frontiers in Genetics

Human Glioma Growth Is Controlled by MicroRNA-10b

(2011) G. Gabriely et al.   CANCER RESEARCH

NF-кB-regulated micro RNAs (miRNAs) in primary human brain cells

(2011) Walter J. Lukiw   EXPERIMENTAL NEUROLOGY

Gene expression levels assessed by CA1 pyramidal neuron and regional hippocampal dissections in Alzheimer's disease

(2011) Stephen D. Ginsberg et al.   NEUROBIOLOGY OF DISEASE

Complete characterization of the microRNAome in a patient with acute myeloid leukemia

(2010) G. Ramsingh et al.   BLOOD

Differential Regulation of Interleukin-1 Receptor-associated Kinase-1 (IRAK-1) and IRAK-2 by MicroRNA-146a and NF-κB in Stressed Human Astroglial Cells and in Alzheimer Disease

(2010) Jian Guo Cui et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mammalian microRNAs predominantly act to decrease target mRNA levels

(2010) Huili Guo et al.   NATURE

The genetic architecture of Alzheimer's disease: beyond APP, PSENs and APOE

(2010) Rita J. Guerreiro et al.   NEUROBIOLOGY OF AGING

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

Micro-RNA abundance and stability in human brain: Specific alterations in Alzheimer's disease temporal lobe neocortex

(2009) Prerna Sethi et al.   NEUROSCIENCE LETTERS

An NF-κB-sensitive Micro RNA-146a-mediated Inflammatory Circuit in Alzheimer Disease and in Stressed Human Brain Cells

(2008) Walter J. Lukiw et al.   JOURNAL OF BIOLOGICAL CHEMISTRY