Loss of CD73 prevents accumulation of alternatively activated macrophages and the formation of prefibrotic macrophage clusters in irradiated lungs

Therapy with Multipotent Mesenchymal Stromal Cells Protects Lungs from Radiation-Induced Injury and Reduces the Risk of Lung Metastasis

(2016) Diana Klein et al.   ANTIOXIDANTS & REDOX SIGNALING

Extracellular Adenosine Production by ecto-5'-Nucleotidase (CD73) Enhances Radiation-Induced Lung Fibrosis

(2016) F. Wirsdo rfer et al.   CANCER RESEARCH

Adenosine A2A receptor plays an important role in radiation-induced dermal injury

(2016) Miguel Perez-Aso et al.   FASEB JOURNAL

Macrophages in Tissue Repair, Regeneration, and Fibrosis

(2016) Thomas A. Wynn et al.   IMMUNITY

Effects of IL-4 on pulmonary fibrosis and the accumulation and phenotype of macrophage subpopulations following thoracic irradiation

(2016) Angela M. Groves et al.   INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Signaling pathways involving adenosine A2A and A2B receptors in wound healing and fibrosis

(2016) Gibran Shaikh et al.   Purinergic Signalling

TGF-β induces M2-like macrophage polarization via SNAIL-mediated suppression of a pro-inflammatory phenotype

(2016) Fan Zhang et al.   Oncotarget

The Role of Lymphocytes in Radiotherapy-Induced Adverse Late Effects in the Lung

(2016) Florian Wirsdörfer et al.   Frontiers in Immunology

Deletion of ADORA2B from myeloid cells dampens lung fibrosis and pulmonary hypertension

(2015) Harry Karmouty-Quintana et al.   FASEB JOURNAL

An Experimental Model-Based Exploration of Cytokines in Ablative Radiation-Induced Lung Injury In Vivo and In Vitro

(2015) Zhen-Yu Hong et al.   LUNG

Understanding the Mysterious M2 Macrophage through Activation Markers and Effector Mechanisms

(2015) Tamás Rőszer   MEDIATORS OF INFLAMMATION

Whole-Lung Irradiation Results in Pulmonary Macrophage Alterations that are Subpopulation and Strain Specific

(2015) Angela M. Groves et al.   RADIATION RESEARCH

Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines

(2014) Peter J. Murray et al.   IMMUNITY

A Novel Mechanism of B Cell–Mediated Immune Suppression through CD73 Expression and Adenosine Production

(2014) Hiroaki Kaku et al.   JOURNAL OF IMMUNOLOGY

Thorax irradiation triggers a local and systemic accumulation of immunosuppressive CD4+ FoxP3+ regulatory T cells

(2014) Florian Wirsdörfer et al.   Radiation Oncology

Flow Cytometric Analysis of Macrophages and Dendritic Cell Subsets in the Mouse Lung

(2013) Alexander V. Misharin et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Adenosine A2B Receptor and Hyaluronan Modulate Pulmonary Hypertension Associated with Chronic Obstructive Pulmonary Disease

(2013) Harry Karmouty-Quintana et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

The Adenosine-Dependent Angiogenic Switch of Macrophages to an M2-Like Phenotype is Independent of Interleukin-4 Receptor Alpha (IL-4Rα) Signaling

(2013) Christopher James Ferrante et al.   INFLAMMATION

Adenosine augments IL-10-induced STAT3 signaling in M2c macrophages

(2013) Balázs Koscsó et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Mesenchymal stem cells inhibit cutaneous radiation-induced fibrosis by suppressing chronic inflammation

(2013) Jason A. Horton et al.   STEM CELLS

Peritoneal macrophages mediated delivery of chitosan/siRNA nanoparticle to the lesion site in a murine radiation-induced fibrosis model

(2012) Isabel Nawroth et al.   ACTA ONCOLOGICA

Regulation of Macrophage Function by Adenosine

(2012) György Haskó et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Macrophage plasticity and polarization: in vivo veritas

(2012) Antonio Sica et al.   JOURNAL OF CLINICAL INVESTIGATION

PAI-1 promotes the accumulation of exudate macrophages and worsens pulmonary fibrosis following type II alveolar epithelial cell injury

(2012) John J Osterholzer et al.   JOURNAL OF PATHOLOGY

Macrophage plasticity and polarization in tissue repair and remodelling

(2012) Alberto Mantovani et al.   JOURNAL OF PATHOLOGY

The TGF-β co-receptor endoglin regulates macrophage infiltration and cytokine production in the irradiated mouse kidney

(2012) Marion Scharpfenecker et al.   RADIOTHERAPY AND ONCOLOGY

Radiation-induced changes in breathing frequency and lung histology of C57BL/6J mice are time- and dose-dependent

(2012) T. Eldh et al.   STRAHLENTHERAPIE UND ONKOLOGIE

Ly6ChiMonocytes Direct Alternatively Activated Profibrotic Macrophage Regulation of Lung Fibrosis

(2011) Michael A. Gibbons et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Adenosine promotes alternative macrophage activation via A2A and A2B receptors

(2011) Balázs Csóka et al.   FASEB JOURNAL

The Development of Classically and Alternatively Activated Macrophages Has Different Effects on The Varied Stages of Radiation-induced Pulmonary Injury in Mice

(2011) Hui ZHANG et al.   JOURNAL OF RADIATION RESEARCH

New insights into the molecular pathology of radiation-induced pneumopathy

(2011) Federica Cappuccini et al.   RADIOTHERAPY AND ONCOLOGY

Severe Pulmonary Toxicity After Myeloablative Conditioning Using Total Body Irradiation: An Assessment of Risk Factors

(2010) Chris R. Kelsey et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Distinct Roles for the A2B Adenosine Receptor in Acute and Chronic Stages of Bleomycin-Induced Lung Injury

(2010) Y. Zhou et al.   JOURNAL OF IMMUNOLOGY

Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm

(2010) Subhra K Biswas et al.   NATURE IMMUNOLOGY

Alterations in Adenosine Metabolism and Signaling in Patients with Chronic Obstructive Pulmonary Disease and Idiopathic Pulmonary Fibrosis

(2010) Yang Zhou et al.   PLoS One

Radiation Pulmonary Toxicity: From Mechanisms to Management

(2010) Paul R. Graves et al.   SEMINARS IN RADIATION ONCOLOGY

Adenosine and osteopontin contribute to the development of chronic obstructive pulmonary disease

(2009) Daniel J. Schneider et al.   FASEB JOURNAL

Gene Expression Profiling Distinguishes Radiation-Induced Fibrosing Alveolitis from Alveolitis in Mice

(2009) Alexandra Paun et al.   RADIATION RESEARCH

The Adenosine A2a Receptor Inhibits Matrix-Induced Inflammation in a Novel Fashion

(2008) Kara A. Scheibner et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Division of labor between dendritic cell subsets of the lung

(2008) C H GeurtsvanKessel et al.   Mucosal Immunology

Adenosine receptors: therapeutic aspects for inflammatory and immune diseases

(2008) György Haskó et al.   NATURE REVIEWS DRUG DISCOVERY