Activation of transient receptor potential vanilloid 1 by lipoxygenase metabolites depends on PKC phosphorylation

Tyrosine Residue in the TRPV1 Vanilloid Binding Pocket Regulates Deactivation Kinetics

(2016) Rakesh Kumar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

DREADDs for Neuroscientists

(2016) Bryan L. Roth   NEURON

Structural insights into the mechanism of activation of the TRPV1 channel by a membrane-bound tarantula toxin

(2016) Chanhyung Bae et al.   eLife

Mechanism for phosphoinositide selectivity and activation of TRPV1 ion channels

(2015) Carmen A. Ufret-Vincenty et al.   JOURNAL OF GENERAL PHYSIOLOGY

The role of slow and persistent TTX-resistant sodium currents in acute tumor necrosis factor-α-mediated increase in nociceptors excitability

(2015) Sagi Gudes et al.   JOURNAL OF NEUROPHYSIOLOGY

Phosphoinositide regulation of TRPV1 revisited

(2015) Tibor Rohacs   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

The pain receptor TRPV1 displays agonist-dependent activation stoichiometry

(2015) Adina Hazan et al.   Scientific Reports

The functional and anatomical dissection of somatosensory subpopulations using mouse genetics

(2014) Claire E. Le Pichon et al.   Frontiers in Neuroanatomy

TRP Channels and Pain

(2013) David Julius   Annual Review of Cell and Developmental Biology

DREADDs: novel tools for drug discovery and development

(2013) Hyeong-Min Lee et al.   DRUG DISCOVERY TODAY

Activity-dependent silencing reveals functionally distinct itch-generating sensory neurons

(2013) David P Roberson et al.   NATURE NEUROSCIENCE

TRPV1 Channels Are Intrinsically Heat Sensitive and Negatively Regulated by Phosphoinositide Lipids

(2013) Erhu Cao et al.   NEURON

Monoacylglycerols Activate TRPV1 – A Link between Phospholipase C and TRPV1

(2013) Peter M. Zygmunt et al.   PLoS One

TRP-channels as key integrators of lipid pathways in nociceptive neurons

(2013) Marco Sisignano et al.   PROGRESS IN LIPID RESEARCH

Direct inhibition of the cold-activated TRPM8 ion channel by Gαq

(2012) Xuming Zhang et al.   NATURE CELL BIOLOGY

Sensory and Signaling Mechanisms of Bradykinin, Eicosanoids, Platelet-Activating Factor, and Nitric Oxide in Peripheral Nociceptors

(2012) Gábor Pethő et al.   PHYSIOLOGICAL REVIEWS

Gαq/11 signaling tonically modulates nociceptor function and contributes to activity-dependent sensitization

(2011) Anke Tappe-Theodor et al.   PAIN

A Bivalent Tarantula Toxin Activates the Capsaicin Receptor, TRPV1, by Targeting the Outer Pore Domain

(2010) Christopher J. Bohlen et al.   CELL

The acute nociceptive signals induced by bradykinin in rat sensory neurons are mediated by inhibition of M-type K+ channels and activation of Ca2+-activated Cl– channels

(2010) Boyi Liu et al.   JOURNAL OF CLINICAL INVESTIGATION

The History of theDrosophilaTRP Channel: The Birth of a New Channel Superfamily

(2010) Baruch Minke   JOURNAL OF NEUROGENETICS

Histamine Influences Body Temperature by Acting at H1and H3 Receptors on Distinct Populations of Preoptic Neurons

(2010) E. G. Lundius et al.   JOURNAL OF NEUROSCIENCE

Modulation of single-channel properties of TRPV1 by phosphorylation

(2010) Milena Studer et al.   JOURNAL OF PHYSIOLOGY-LONDON

Resolvins RvE1 and RvD1 attenuate inflammatory pain via central and peripheral actions

(2010) Zhen-Zhong Xu et al.   NATURE MEDICINE

Understanding inflammatory pain: ion channels contributing to acute and chronic nociception

(2010) John E. Linley et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Cellular and Molecular Mechanisms of Pain

(2009) Allan I. Basbaum et al.   CELL

PKC and PLA2: Probing the complexities of the calcium network

(2009) Damian B. van Rossum et al.   CELL CALCIUM

Voltage-clamp and current-clamp recordings from mammalian DRG neurons

(2009) Theodore R Cummins et al.   Nature Protocols

Transient receptor potential channels meet phosphoinositides

(2008) Bernd Nilius et al.   EMBO JOURNAL

Phospholipase C Mediated Modulation of TRPV1 Channels

(2008) Tibor Rohacs et al.   MOLECULAR NEUROBIOLOGY

Direct Activation of Transient Receptor Potential Vanilloid 1(TRPV1) by Diacylglycerol (DAG)

(2008) Dong Ho Woo et al.   Molecular Pain

Functional lipidomics. Calcium-independent activation of endocannabinoid/endovanilloid lipid signalling in sensory neurons by protein kinases C and A and thrombin

(2008) Vittorio Vellani et al.   NEUROPHARMACOLOGY