The aquaporin-4 water channel as a potential drug target in neurological disorders
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
The aquaporin-4 water channel as a potential drug target in neurological disorders
Authors
Keywords
-
Journal
EXPERT OPINION ON THERAPEUTIC TARGETS
Volume 21, Issue 12, Pages 1161-1170
Publisher
Informa UK Limited
Online
2017-10-26
DOI
10.1080/14728222.2017.1398236
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Test of the 'glymphatic' hypothesis demonstrates diffusive and aquaporin-4-independent solute transport in rodent brain parenchyma
- (2017) Alex J Smith et al. eLife
- Improved long-term outcome after transient cerebral ischemia in aquaporin-4 knockout mice
- (2016) Lorenz Hirt et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Spatial model of convective solute transport in brain extracellular space does not support a “glymphatic” mechanism
- (2016) Byung-Ju Jin et al. JOURNAL OF GENERAL PHYSIOLOGY
- Of Bugs and Drugs: How the Microbiome Controls Responsiveness to Antitumor Immunotherapy
- (2015) Mandy L. Ford AMERICAN JOURNAL OF TRANSPLANTATION
- Challenging AQP4 druggability for NMO-IgG antibody binding using molecular dynamics and molecular interaction fields
- (2015) Giuseppe Felice Mangiatordi et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Superresolution Imaging of Aquaporin-4 Cluster Size in Antibody-Stained Paraffin Brain Sections
- (2015) Alex J. Smith et al. BIOPHYSICAL JOURNAL
- Aquaporin-4 regulates the velocity and frequency of cortical spreading depression in mice
- (2015) Xiaoming Yao et al. GLIA
- Mildly Reduced Brain Swelling and Improved Neurological Outcome in Aquaporin-4 Knockout Mice following Controlled Cortical Impact Brain Injury
- (2015) Xiaoming Yao et al. JOURNAL OF NEUROTRAUMA
- Literature WatchImplications for transplantation
- (2014) A. Joseph Tector et al. AMERICAN JOURNAL OF TRANSPLANTATION
- Aggregation state determines the localization and function of M1– and M23–aquaporin-4 in astrocytes
- (2014) Alex J. Smith et al. JOURNAL OF CELL BIOLOGY
- Aquaporins: important but elusive drug targets
- (2014) Alan S. Verkman et al. NATURE REVIEWS DRUG DISCOVERY
- Neuroprotective effect of aquaporin-4 deficiency in a mouse model of severe global cerebral ischemia produced by transient 4-vessel occlusion
- (2014) Gökhan Akdemir et al. NEUROSCIENCE LETTERS
- Greatly improved survival and neuroprotection in aquaporin-4-knockout mice following global cerebral ischemia
- (2013) Ryuichi Katada et al. FASEB JOURNAL
- Small-molecule inhibitors of NMO-IgG binding to aquaporin-4 reduce astrocyte cytotoxicity in neuromyelitis optica
- (2012) Lukmanee Tradtrantip et al. FASEB JOURNAL
- Super-resolution imaging of aquaporin-4 orthogonal arrays of particles in cell membranes
- (2012) A. Rossi et al. JOURNAL OF CELL SCIENCE
- Aquaporin-4–dependent K+and water transport modeled in brain extracellular space following neuroexcitation
- (2012) Byung-Ju Jin et al. JOURNAL OF GENERAL PHYSIOLOGY
- Aquaporin 4 and neuromyelitis optica
- (2012) Marios C Papadopoulos et al. LANCET NEUROLOGY
- A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid
- (2012) J. J. Iliff et al. Science Translational Medicine
- Anti-Aquaporin-4 monoclonal antibody blocker therapy for neuromyelitis optica
- (2011) Lukmanee Tradtrantip et al. ANNALS OF NEUROLOGY
- Aquaporins in Clinical Medicine
- (2011) A.S. Verkman Annual Review of Medicine
- Model of Aquaporin-4 Supramolecular Assembly in Orthogonal Arrays Based on Heterotetrameric Association of M1-M23 Isoforms
- (2011) Byung-Ju Jin et al. BIOPHYSICAL JOURNAL
- Proinflammatory role of aquaporin-4 in autoimmune neuroinflammation
- (2011) Lihua Li et al. FASEB JOURNAL
- Aquaporin-4 Mz isoform: Brain expression, supramolecular assembly and neuromyelitis optica antibody binding
- (2011) Andrea Rossi et al. GLIA
- Impact of aquaporin-4 channels on K+ buffering and gap junction coupling in the hippocampus
- (2011) Susan Strohschein et al. GLIA
- Binding Affinity and Specificity of Neuromyelitis Optica Autoantibodies to Aquaporin-4 M1/M23 Isoforms and Orthogonal Arrays
- (2011) Jonathan M. Crane et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Impairment of Select Forms of Spatial Memory and Neurotrophin-Dependent Synaptic Plasticity by Deletion of Glial Aquaporin-4
- (2011) V. A. Skucas et al. JOURNAL OF NEUROSCIENCE
- An aquaporin-4/transient receptor potential vanilloid 4 (AQP4/TRPV4) complex is essential for cell-volume control in astrocytes
- (2011) V. Benfenati et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Microfiberoptic Measurement of Extracellular Space Volume in Brain and Tumor Slices Based on Fluorescent Dye Partitioning
- (2010) Hua Zhang et al. BIOPHYSICAL JOURNAL
- Pretreatment with a novel aquaporin 4 inhibitor, TGN-020, significantly reduces ischemic cerebral edema
- (2010) Hironaka Igarashi et al. NEUROLOGICAL SCIENCES
- Critical role of aquaporin-4 (AQP4) in astrocytic Ca2+ signaling events elicited by cerebral edema
- (2010) A. S. Thrane et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Automated Cell-Based Assay for Screening of Aquaporin Inhibitors
- (2009) Maria Grazia Mola et al. ANALYTICAL CHEMISTRY
- Live Cell Analysis of Aquaporin-4 M1/M23 Interactions and Regulated Orthogonal Array Assembly in Glial Cells
- (2009) Jonathan M. Crane et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Evidences for a Leaky Scanning Mechanism for the Synthesis of the Shorter M23 Protein Isoform of Aquaporin-4
- (2009) Andrea Rossi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Determinants of aquaporin-4 assembly in orthogonal arrays revealed by live-cell single-molecule fluorescence imaging
- (2009) J. M. Crane et al. JOURNAL OF CELL SCIENCE
- Inhibition of Aquaporin-1 and Aquaporin-4 Water Permeability by a Derivative of the Loop Diuretic Bumetanide Acting at an Internal Pore-Occluding Binding Site
- (2009) E. Migliati et al. MOLECULAR PHARMACOLOGY
- Crystal structure of human aquaporin 4 at 1.8 A and its mechanism of conductance
- (2009) J. D. Ho et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Lack of aquaporin-4 water transport inhibition by antiepileptics and arylsulfonamides
- (2008) Baoxue Yang et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Inhibition of Aquaporin 4 by antiepileptic drugs
- (2008) Vincent J. Huber et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Identification of Aquaporin 4 inhibitors using in vitro and in silico methods
- (2008) Vincent J. Huber et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Greatly improved neurological outcome after spinal cord compression injury in AQP4-deficient mice
- (2008) S. Saadoun et al. BRAIN
- Impaired olfaction in mice lacking aquaporin-4 water channels
- (2008) Daniel C. Lu et al. FASEB JOURNAL
- Glial Cell Aquaporin-4 Overexpression in Transgenic Mice Accelerates Cytotoxic Brain Swelling
- (2008) Baoxue Yang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search