Particle morphology: an important factor affecting drug delivery by nanocarriers into solid tumors

Radiation therapy primes tumors for nanotherapeutic delivery via macrophage-mediated vascular bursts

(2017) Miles A. Miller et al.   Science Translational Medicine

Diffusion and Uptake of Tobacco Mosaic Virus as Therapeutic Carrier in Tumor Tissue: Effect of Nanoparticle Aspect Ratio

(2016) Paul L. Chariou et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Tunable High Aspect Ratio Iron Oxide Nanorods for Enhanced Hyperthermia

(2016) Raja Das et al.   Journal of Physical Chemistry C

An injectable nanoparticle generator enhances delivery of cancer therapeutics

(2016) Rong Xu et al.   NATURE BIOTECHNOLOGY

Vascular bursts enhance permeability of tumour blood vessels and improve nanoparticle delivery

(2016) Yu Matsumoto et al.   Nature Nanotechnology

Anomalously Fast Diffusion of Targeted Carbon Nanotubes in Cellular Spheroids

(2015) Yichun Wang et al.   ACS Nano

Elasticity of Nanoparticles Influences Their Blood Circulation, Phagocytosis, Endocytosis, and Targeting

(2015) Aaron C. Anselmo et al.   ACS Nano

Soft Discoidal Polymeric Nanoconstructs Resist Macrophage Uptake and Enhance Vascular Targeting in Tumors

(2015) Jaehong Key et al.   ACS Nano

Ultrasmall Gold Nanorod Vesicles with Enhanced Tumor Accumulation and Fast Excretion from the Body for Cancer Therapy

(2015) Jibin Song et al.   ADVANCED MATERIALS

Nanoparticle–blood interactions: the implications on solid tumour targeting

(2015) James Lazarovits et al.   CHEMICAL COMMUNICATIONS

The Impact of Aspect Ratio on the Biodistribution and Tumor Homing of Rigid Soft-Matter Nanorods

(2015) Sourabh Shukla et al.   Advanced Healthcare Materials

Effect of Shape, Size, and Aspect Ratio on Nanoparticle Penetration and Distribution inside Solid Tissues Using 3D Spheroid Models

(2015) Rachit Agarwal et al.   Advanced Healthcare Materials

Advantages and risks of nanotechnologies in cancer patients and occupationally exposed workers

(2014) Monica Lamberti et al.   Expert Opinion on Drug Delivery

The importance of nanoparticle shape in cancer drug delivery

(2014) Nghia P Truong et al.   Expert Opinion on Drug Delivery

Selective uptake of single-walled carbon nanotubes by circulating monocytes for enhanced tumour delivery

(2014) Bryan Ronain Smith et al.   Nature Nanotechnology

Linear-dendritic drug conjugates forming long-circulating nanorods for cancer-drug delivery

(2013) Zhuxian Zhou et al.   BIOMATERIALS

Quantifying uncertainties in the microvascular transport of nanoparticles

(2013) Tae-Rin Lee et al.   Biomechanics and Modeling in Mechanobiology

Challenges and Key Considerations of the Enhanced Permeability and Retention Effect for Nanomedicine Drug Delivery in Oncology

(2013) U. Prabhakar et al.   CANCER RESEARCH

Factors controlling the pharmacokinetics, biodistribution and intratumoral penetration of nanoparticles

(2013) Mark J. Ernsting et al.   JOURNAL OF CONTROLLED RELEASE

Biodistribution and clearance of a filamentous plant virus in healthy and tumor-bearing mice

(2013) Sourabh Shukla et al.   Nanomedicine

Shaping cancer nanomedicine: the effect of particle shape on the in vivo journey of nanoparticles

(2013) Randall Toy et al.   Nanomedicine

PLGA-Carbon Nanotube Conjugates for Intercellular Delivery of Caspase-3 into Osteosarcoma Cells

(2013) Qingsu Cheng et al.   PLoS One

Mammalian cells preferentially internalize hydrogel nanodiscs over nanorods and use shape-specific uptake mechanisms

(2013) R. Agarwal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Different modulated structures of topological defects stabilized by adaptive targeting nanoparticles

(2013) George Cordoyiannis et al.   Soft Matter

On the near-wall accumulation of injectable particles in the microcirculation: smaller is not better

(2013) Tae-Rin Lee et al.   Scientific Reports

Discoidal Porous Silicon Particles: Fabrication and Biodistribution in Breast Cancer Bearing Mice

(2012) Biana Godin et al.   ADVANCED FUNCTIONAL MATERIALS

The preferential targeting of the diseased microvasculature by disk-like particles

(2012) Giulia Adriani et al.   BIOMATERIALS

Solvothermal Synthesis of Tunable Electroactive Magnetite Nanorods by Controlling the Side Reaction

(2012) Haiyan Sun et al.   Journal of Physical Chemistry C

In Vivo Fluorescence Imaging in the Second Near-Infrared Window with Long Circulating Carbon Nanotubes Capable of Ultrahigh Tumor Uptake

(2012) Joshua T. Robinson et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Increased Tumor Homing and Tissue Penetration of the Filamentous Plant Viral Nanoparticle Potato virus X

(2012) Sourabh Shukla et al.   MOLECULAR PHARMACEUTICS

M13 Phage-Functionalized Single-Walled Carbon Nanotubes As Nanoprobes for Second Near-Infrared Window Fluorescence Imaging of Targeted Tumors

(2012) Hyunjung Yi et al.   NANO LETTERS

The Shape Effect of Mesoporous Silica Nanoparticles on Biodistribution, Clearance, and Biocompatibility in Vivo

(2011) Xinglu Huang et al.   ACS Nano

Fluorescent Nanorods and Nanospheres for Real-Time In Vivo Probing of Nanoparticle Shape-Dependent Tumor Penetration

(2011) Vikash P. Chauhan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The effect of surface charge on in vivo biodistribution of PEG-oligocholic acid based micellar nanoparticles

(2011) Kai Xiao et al.   BIOMATERIALS

Synthesis of Nonspherical Mesoporous Silica Ellipsoids with Tunable Aspect Ratios for Magnetic Assisted Assembly and Gene Delivery

(2011) Shaodian Shen et al.   CHEMISTRY OF MATERIALS

Tumour-Specific Uptake of Anti-Cancer Drugs: The Future is Here

(2011) Michele Caraglia et al.   CURRENT DRUG METABOLISM

Theoretical and experimental study of the nanoparticle-driven blue phase stabilisation

(2011) B. Rožič et al.   EUROPEAN PHYSICAL JOURNAL E

Gold nanorod mediated plasmonic photothermal therapy: A tool to enhance macromolecular delivery

(2011) Adam J. Gormley et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Rapid tumoritropic accumulation of systemically injected plateloid particles and their biodistribution

(2011) Anne L. van de Ven et al.   JOURNAL OF CONTROLLED RELEASE

Intratumoral Drug Delivery with Nanoparticulate Carriers

(2011) Hillary Holback et al.   PHARMACEUTICAL RESEARCH

Using mechanobiological mimicry of red blood cells to extend circulation times of hydrogel microparticles

(2011) T. J. Merkel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Reexamination of Active and Passive Tumor Targeting by Using Rod-Shaped Gold Nanocrystals and Covalently Conjugated Peptide Ligands

(2010) Xiaohua Huang et al.   ACS Nano

Diffusion Anisotropy in Collagen Gels and Tumors: The Effect of Fiber Network Orientation

(2010) Triantafyllos Stylianopoulos et al.   BIOPHYSICAL JOURNAL

Diffusion of Particles in the Extracellular Matrix: The Effect of Repulsive Electrostatic Interactions

(2010) Triantafyllos Stylianopoulos et al.   BIOPHYSICAL JOURNAL

Sustained Small Interfering RNA Delivery by Mesoporous Silicon Particles

(2010) Takemi Tanaka et al.   CANCER RESEARCH

Nanoparticles for Tumor Targeted Therapies and Their Pharmacokinetics

(2010) Jianqiu Wang et al.   CURRENT DRUG METABOLISM

Targeting of drugs and nanoparticles to tumors

(2010) Erkki Ruoslahti et al.   JOURNAL OF CELL BIOLOGY

The Use of Nanoparticles to Control Oral Biofilm Formation

(2010) R.P. Allaker   JOURNAL OF DENTAL RESEARCH

Intra-organ biodistribution of gold nanoparticles using intrinsic two-photon-induced photoluminescence

(2010) Jaesook Park et al.   LASERS IN SURGERY AND MEDICINE

Analysis of the Migration of Rigid Polymers and Nanorods in a Rotating Viscometric Flow

(2010) Joontaek Park et al.   MACROMOLECULES

Improved cellular uptake of functionalized single-walled carbon nanotubes

(2010) A Antonelli et al.   NANOTECHNOLOGY

Computer simulation of the translocation of nanoparticles with different shapes across a lipid bilayer

(2010) Kai Yang et al.   Nature Nanotechnology

Delivering nanomedicine to solid tumors

(2010) Rakesh K. Jain et al.   Nature Reviews Clinical Oncology

In Vivo Distribution of Polymeric Nanoparticles at the Whole-Body, Tumor, and Cellular Levels

(2010) Helen Lee et al.   PHARMACEUTICAL RESEARCH

Nanoparticle-induced widening of the temperature range of liquid-crystalline blue phases

(2010) Eva Karatairi et al.   PHYSICAL REVIEW E

Paradoxical glomerular filtration of carbon nanotubes

(2010) A. Ruggiero et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The use of nanoparticles in electroanalysis: an updated review

(2009) Fallyn W. Campbell et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

The association of silicon microparticles with endothelial cells in drug delivery to the vasculature

(2009) Rita E. Serda et al.   BIOMATERIALS

Selective Filtering of Particles by the Extracellular Matrix: An Electrostatic Bandpass

(2009) Oliver Lieleg et al.   BIOPHYSICAL JOURNAL

Effect of surface charge of magnetite nanoparticles on their internalization into breast cancer and umbilical vein endothelial cells

(2009) Tetsuya Osaka et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

The effects of PEG grafting level and injection dose on gold nanorod biodistribution in the tumor-bearing mice

(2009) Yasuyuki Akiyama et al.   JOURNAL OF CONTROLLED RELEASE

Size and shape effects in the biodistribution of intravascularly injected particles

(2009) P. Decuzzi et al.   JOURNAL OF CONTROLLED RELEASE

Flexible Filaments forin VivoImaging and Delivery: Persistent Circulation of Filomicelles Opens the Dosage Window for Sustained Tumor Shrinkage

(2009) David A. Christian et al.   MOLECULAR PHARMACEUTICS

Tumor-associated macrophages are predominant carriers of cyclodextrin-based nanoparticles into gliomas

(2009) Darya Alizadeh et al.   Nanomedicine-Nanotechnology Biology and Medicine

Shaping nano-/micro-particles for enhanced vascular interaction in laminar flows

(2009) Sei-Young Lee et al.   NANOTECHNOLOGY

Understanding biophysicochemical interactions at the nano–bio interface

(2009) Andre E. Nel et al.   NATURE MATERIALS

Antibody tumor penetration: Transport opposed by systemic and antigen-mediated clearance

(2008) Greg M. Thurber et al.   ADVANCED DRUG DELIVERY REVIEWS

Magnetic Iron Oxide Nanoworms for Tumor Targeting and Imaging

(2008) Ji-Ho Park et al.   ADVANCED MATERIALS

Shape Effects of Nanoparticles Conjugated with Cell-Penetrating Peptides (HIV Tat PTD) on CHO Cell Uptake

(2008) Ke Zhang et al.   BIOCONJUGATE CHEMISTRY

Gold nanorod assisted near-infrared plasmonic photothermal therapy (PPTT) of squamous cell carcinoma in mice

(2008) Erin B. Dickerson et al.   CANCER LETTERS

Drug Delivery with Carbon Nanotubes for In vivo Cancer Treatment

(2008) Z. Liu et al.   CANCER RESEARCH

The effect of shape on the margination dynamics of non-neutrally buoyant particles in two-dimensional shear flows

(2008) F. Gentile et al.   JOURNAL OF BIOMECHANICS

Preclinical Studies To Understand Nanoparticle Interaction with the Immune System and Its Potential Effects on Nanoparticle Biodistribution

(2008) Marina A. Dobrovolskaia et al.   MOLECULAR PHARMACEUTICS