“All-Water” Synthesis of β-Amino α,α-Difluoro Ketones from Fluorinated Enol Silyl Ethers and Imines

Catalytic intermolecular hydroaminations of unactivated olefins with secondary alkyl amines

(2017) Andrew J. Musacchio et al.   SCIENCE

Organocatalytic enantioselective Mukaiyama–Mannich reaction of fluorinated enol silyl ethers and cyclic N-sulfonyl ketimines

(2016) Jin-Sheng Yu et al.   Organic Chemistry Frontiers

Advances in Transition-Metal-Mediated Di-and Monofluoroalkylations

(2015) Chuanfa Ni et al.   ACTA CHIMICA SINICA

Michael Addition Catalyzed by Chiral Secondary Amine Phosphoramide Using Fluorinated Silyl Enol Ethers: Formation of Quaternary Carbon Stereocenters

(2015) Jin-Sheng Yu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Metal-Mediated Reformatsky Reaction of Bromodifluoromethyl Ketone and Imine

(2015) Chun-Ru Cao et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

An efficient catalyst-free Mukaiyama-aldol reaction of fluorinated enol silyl ethers with tryptanthrin

(2015) Fu-Min Liao et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Fluorinated enol ethers: their synthesis and reactivity

(2015) M. Decostanzi et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

A highly efficient Mukaiyama–Mannich reaction of N-Boc isatin ketimines and other active cyclic ketimines using difluoroenol silyl ethers catalyzed by Ph3PAuOTf

(2015) Jin-Sheng Yu et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Access to Difluoromethylated Arenes by Pd-Catalyzed Reaction of Arylboronic Acids with Bromodifluoroacetate

(2015) Zhang Feng et al.   ORGANIC LETTERS

Oxidative Trifluoromethylation and Trifluoromethylthiolation Reactions Using (Trifluoromethyl)trimethylsilane as a Nucleophilic CF3 Source

(2014) Lingling Chu et al.   ACCOUNTS OF CHEMICAL RESEARCH

Visible Light-Induced Aromatic Difluoroalkylation

(2014) Jaehun Jung et al.   ADVANCED SYNTHESIS & CATALYSIS

Highly Efficient “On Water” Catalyst-Free Nucleophilic Addition Reactions Using Difluoroenoxysilanes: Dramatic Fluorine Effects

(2014) Jin-Sheng Yu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nickel-Catalyzed Cross-Coupling of Functionalized Difluoromethyl Bromides and Chlorides with Aryl Boronic Acids: A General Method for Difluoroalkylated Arenes

(2014) Yu-Lan Xiao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Selective difluoroalkylation of alkenes by using visible light photoredox catalysis

(2014) Chunghyeon Yu et al.   CHEMICAL COMMUNICATIONS

Synthetic Methods for Compounds Having CF3–S Units on Carbon by Trifluoromethylation, Trifluoromethylthiolation, Triflylation, and Related Reactions

(2014) Xiu-Hua Xu et al.   CHEMICAL REVIEWS

Trifluoromethyltrimethylsilane: Nucleophilic Trifluoromethylation and Beyond

(2014) Xiao Liu et al.   CHEMICAL REVIEWS

Electrophilic Trifluoromethylation by Use of Hypervalent Iodine Reagents

(2014) Julie Charpentier et al.   CHEMICAL REVIEWS

Recent Advances in the Synthetic Application of Difluorocarbene

(2014) Jinbo Hu et al.   SYNTHESIS-STUTTGART

Highly stereoselective construction of adjacent tetrasubstituted carbon stereogenic centres via an organocatalytic Mukaiyama-aldol reaction of monofluorinated silyl enol ethers to isatins

(2014) Yun-Lin Liu et al.   Organic Chemistry Frontiers

Direct Synthesis of Fluorinated Heteroarylether Bioisosteres

(2013) Qianghui Zhou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

“All-water” one-pot diverse synthesis of 1,2-disubstituted benzimidazoles: hydrogen bond driven ‘synergistic electrophile–nucleophile dual activation’ by water

(2013) Damodara N. Kommi et al.   GREEN CHEMISTRY

Catalytic Asymmetric Construction of Stereogenic Carbon Centers that Feature agem-Difluoroalkyl Group

(2013) Yun-Lin Liu et al.   Asian Journal of Organic Chemistry

Copper-catalyzed cross-coupling of bromozinc-difluoromethylphosphonate with iodo/bromo-aryl triazenes

(2013) Zhang Feng et al.   Organic Chemistry Frontiers

Indium-Promoted Reformatsky Reaction: A Straightforward Access to β-Amino and β-Hydroxy α,α-Difluoro Carbonyl Compounds

(2012) Thomas Poisson et al.   JOURNAL OF ORGANIC CHEMISTRY

Asymmetric catalytic Mannich-type reaction of hydrazones with difluoroenoxysilanes using imidazoline-anchored phosphine ligand–zinc(ii) complexes

(2012) Zhiliang Yuan et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Photoredox Catalysis: A Mild, Operationally Simple Approach to the Synthesis of α-Trifluoromethyl Carbonyl Compounds

(2011) Phong V. Pham et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Stereoselective Preparation of 3-Amino-2-fluoro Carboxylic Acid Derivatives, and Their Incorporation in Tetrahydropyrimidin-4(1H)-ones, and in Open-Chain and Cyclic β-Peptides

(2011) Tomohiro Yoshinari et al.   HELVETICA CHIMICA ACTA

Chiral Phosphoric Acid Catalyzed Enantioselective Synthesis of β-Amino-α,α-difluoro Carbonyl Compounds

(2011) Wataru Kashikura et al.   ORGANIC LETTERS

A New Method for Aromatic Difluoromethylation: Copper-Catalyzed Cross-Coupling and Decarboxylation Sequence from Aryl Iodides

(2011) Kenichi Fujikawa et al.   ORGANIC LETTERS

Reaction of aldimines and difluoroenoxysilane, an unexpected protocol for the synthesis of 2,2-difluoro-3-hydroxy-1-ones

(2010) Zhi-Liang Yuan et al.   TETRAHEDRON

Peptide bond mimicry by (E)-alkene and (Z)-fluoroalkene peptide isosteres: synthesis and bioevaluation of α-helical anti-HIV peptide analogues

(2009) Shinya Oishi et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

CuBr-Catalyzed Oxidative Difluoromethylation of Tertiary Amines with Difluoroenol Silyl Ethers

(2009) Lingling Chu et al.   ORGANIC LETTERS

Fluorine in medicinal chemistry

(2007) Sophie Purser et al.   CHEMICAL SOCIETY REVIEWS