Early-life stress links 5-hydroxymethylcytosine to anxiety-related behaviors

Genome-wide alterations in hippocampal 5-hydroxymethylcytosine links plasticity genes to acute stress

(2016) Sisi Li et al.   NEUROBIOLOGY OF DISEASE

Sex-specific hippocampal 5-hydroxymethylcytosine is disrupted in response to acute stress

(2016) Ligia A. Papale et al.   NEUROBIOLOGY OF DISEASE

A Cross-Disorder Method to Identify Novel Candidate Genes for Developmental Brain Disorders

(2016) Andrea J. Gonzalez-Mantilla et al.   JAMA Psychiatry

ChIPseeker: an R/Bioconductor package for ChIP peak annotation, comparison and visualization

(2015) Guangchuang Yu et al.   BIOINFORMATICS

Brain-Derived Neurotrophic Factor Epigenetic Modifications Associated with Schizophrenia-like Phenotype Induced by Prenatal Stress in Mice

(2015) Erbo Dong et al.   BIOLOGICAL PSYCHIATRY

Diverse glial cell line-derived neurotrophic factor (GDNF) support between mania and schizophrenia: A comparative study in four major psychiatric disorders

(2015) Z. Tunca et al.   EUROPEAN PSYCHIATRY

Genome-wide disruption of 5-hydroxymethylcytosine in a mouse model of autism

(2015) Ligia A. Papale et al.   HUMAN MOLECULAR GENETICS

Role of Tet1 and 5-hydroxymethylcytosine in cocaine action

(2015) Jian Feng et al.   NATURE NEUROSCIENCE

Fetal Alcohol Programming of Hypothalamic Proopiomelanocortin System by Epigenetic Mechanisms and Later Life Vulnerability to Stress

(2014) Rola Bekdash et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Influence of DGKH variants on amygdala volume in patients with bipolar affective disorder and schizophrenia

(2014) S. Kittel-Schneider et al.   EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE

Differentially Methylated Plasticity Genes in the Amygdala of Young Primates Are Linked to Anxious Temperament, an at Risk Phenotype for Anxiety and Depressive Disorders

(2014) R. S. Alisch et al.   JOURNAL OF NEUROSCIENCE

A polygenic burden of rare disruptive mutations in schizophrenia

(2014) Shaun M. Purcell et al.   NATURE

The role of DNA methylation in stress-related psychiatric disorders

(2014) Torsten Klengel et al.   NEUROPHARMACOLOGY

Increased binding of MeCP2 to the GAD1 and RELN promoters may be mediated by an enrichment of 5-hmC in autism spectrum disorder (ASD) cerebellum

(2014) A Zhubi et al.   Translational Psychiatry

The emerging role of 5-hydroxymethylcytosine in neurodegenerative diseases

(2014) Sahar Al-Mahdawi et al.   Frontiers in Neuroscience

Cognitive, emotional and neurochemical effects of repeated maternal separation in adolescent rats

(2013) Man Li et al.   BRAIN RESEARCH

Cytosine modifications in neurodevelopment and diseases

(2013) Bing Yao et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Genome-wide alteration of 5-hydroxymethylcytosine in a mouse model of fragile X-associated tremor/ataxia syndrome

(2013) Bing Yao et al.   HUMAN MOLECULAR GENETICS

Genome-wide loss of 5-hmC is a novel epigenetic feature of Huntington's disease

(2013) Fengli Wang et al.   HUMAN MOLECULAR GENETICS

TET enzymes, TDG and the dynamics of DNA demethylation

(2013) Rahul M. Kohli et al.   NATURE

Consistent decrease in global DNA methylation and hydroxymethylation in the hippocampus of Alzheimer's disease patients

(2013) Leonidas Chouliaras et al.   NEUROBIOLOGY OF AGING

Increased 5-Methylcytosine and Decreased 5-Hydroxymethylcytosine Levels are Associated with Reduced Striatal A2AR Levels in Huntington’s Disease

(2013) Izaskun Villar-Menéndez et al.   NEUROMOLECULAR MEDICINE

Methylation of the SLC6a2 Gene Promoter in Major Depression and Panic Disorder

(2013) Richard Bayles et al.   PLoS One

MeCP2 Binds to 5hmC Enriched within Active Genes and Accessible Chromatin in the Nervous System

(2012) Marian Mellén et al.   CELL

5-hmC in the brain is abundant in synaptic genes and shows differences at the exon-intron boundary

(2012) Tarang Khare et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Stress and the developing adolescent brain

(2012) L. Eiland et al.   NEUROSCIENCE

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

(2012) Guangchuang Yu et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Multiplex Targeted Sequencing Identifies Recurrently Mutated Genes in Autism Spectrum Disorders

(2012) B. J. O'Roak et al.   SCIENCE

DNA methylation in schizophrenia: progress and challenges of epigenetic studies

(2012) Masaki Nishioka et al.   Genome Medicine

DREME: motif discovery in transcription factor ChIP-seq data

(2011) Timothy L. Bailey   BIOINFORMATICS

RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome

(2011) Bo Li et al.   BMC BIOINFORMATICS

A Statistical Framework for the Analysis of ChIP-Seq Data

(2011) Pei Fen Kuan et al.   JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION

5-hmC–mediated epigenetic dynamics during postnatal neurodevelopment and aging

(2011) Keith E Szulwach et al.   NATURE NEUROSCIENCE

Integrating 5-Hydroxymethylcytosine into the Epigenomic Landscape of Human Embryonic Stem Cells

(2011) Keith E. Szulwach et al.   PLoS Genetics

The Neural/Immune Gene Ontology: clipping the Gene Ontology for neurological and immunological systems

(2010) Nophar Geifman et al.   BMC BIOINFORMATICS

Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine

(2010) Chun-Xiao Song et al.   NATURE BIOTECHNOLOGY

Major Depressive Disorder and Hypothalamic-Pituitary-Adrenal Axis Activity

(2009) Sophie A. Vreeburg et al.   ARCHIVES OF GENERAL PSYCHIATRY

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

Transcription factor AP-2β genotype and psychosocial adversity in relation to adolescent depressive symptomatology

(2009) Kent W. Nilsson et al.   JOURNAL OF NEURAL TRANSMISSION

Kruppel-Like Factor 9 Is Necessary for Late-Phase Neuronal Maturation in the Developing Dentate Gyrus and during Adult Hippocampal Neurogenesis

(2009) K. N. Scobie et al.   JOURNAL OF NEUROSCIENCE

Transcriptional and Electrophysiological Maturation of Neocortical Fast-Spiking GABAergic Interneurons

(2009) B. W. Okaty et al.   JOURNAL OF NEUROSCIENCE

The Nuclear DNA Base 5-Hydroxymethylcytosine Is Present in Purkinje Neurons and the Brain

(2009) S. Kriaucionis et al.   SCIENCE

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

(2009) Ben Langmead et al.   GENOME BIOLOGY

GABAA Receptor Promoter Hypermethylation in Suicide Brain: Implications for the Involvement of Epigenetic Processes

(2008) Michael O. Poulter et al.   BIOLOGICAL PSYCHIATRY

Design and analysis of ChIP-seq experiments for DNA-binding proteins

(2008) Peter V Kharchenko et al.   NATURE BIOTECHNOLOGY