Fetal Alcohol Programming of Hypothalamic Proopiomelanocortin System by Epigenetic Mechanisms and Later Life Vulnerability to Stress

Fetal Alcohol Exposure Disrupts Metabolic Signaling in Hypothalamic Proopiomelanocortin Neurons via a Circadian Mechanism in Male Mice

(2014) Maria A. Agapito et al.   ENDOCRINOLOGY

Intergenerational effects of prenatal ethanol on glucose tolerance and insulin response

(2014) Kathryn M. Harper et al.   PHYSIOLOGICAL GENOMICS

Prenatal ethanol exposure enhances the susceptibility to metabolic syndrome in offspring rats by HPA axis-associated neuroendocrine metabolic programming

(2014) L.P. Xia et al.   TOXICOLOGY LETTERS

Alcohol Exposure in Utero Increases Susceptibility to Prostate Tumorigenesis in Rat Offspring

(2013) Sengottuvelan Murugan et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Gestational Choline Supplementation Normalized Fetal Alcohol-Induced Alterations in Histone Modifications, DNA Methylation, and Proopiomelanocortin (POMC) Gene Expression in β-Endorphin-Producing POMC Neurons of the Hypothalamus

(2013) Rola A. Bekdash et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Effects of Alcohol on the Endocrine System

(2013) Nadia Rachdaoui et al.   ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA

Glucocorticoid feedback uncovers retrograde opioid signaling at hypothalamic synapses

(2013) Jaclyn I Wamsteeker Cusulin et al.   NATURE NEUROSCIENCE

Epigenetic mechanisms of drug addiction

(2013) Eric J. Nestler   NEUROPHARMACOLOGY

Male Germline Transmits Fetal Alcohol Adverse Effect on Hypothalamic Proopiomelanocortin Gene Across Generations

(2012) Dmitry Govorko et al.   BIOLOGICAL PSYCHIATRY

Gene Coexpression Networks in Human Brain Identify Epigenetic Modifications in Alcohol Dependence

(2012) I. Ponomarev et al.   JOURNAL OF NEUROSCIENCE

Hypothalamic neuropeptides and the regulation of appetite

(2012) Jennifer A. Parker et al.   NEUROPHARMACOLOGY

Prenatal alcohol exposure alters the course and severity of adjuvant-induced arthritis in female rats

(2011) Xingqi Zhang et al.   BRAIN BEHAVIOR AND IMMUNITY

Hypothalamic proopiomelanocortin processing and the regulation of energy balance

(2011) Sharon L. Wardlaw   EUROPEAN JOURNAL OF PHARMACOLOGY

Genome-wide analysis of 5-hydroxymethylcytosine distribution reveals its dual function in transcriptional regulation in mouse embryonic stem cells

(2011) H. Wu et al.   GENES & DEVELOPMENT

CpG islands and the regulation of transcription

(2011) A. M. Deaton et al.   GENES & DEVELOPMENT

Clinical and pathological features of alcohol-related brain damage

(2011) Natalie M. Zahr et al.   Nature Reviews Neurology

Modulation of Brain β-Endorphin Concentration by the Specific Part of the Y Chromosome in Mice

(2011) Michel Botbol et al.   PLoS One

Alcohol Exposure Decreases CREB Binding Protein Expression and Histone Acetylation in the Developing Cerebellum

(2011) Weixiang Guo et al.   PLoS One

MicroRNAs: Master Regulators of Ethanol Abuse and Toxicity?

(2010) Rajesh C. Miranda et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Fetal Alcohol Exposure Increases Mammary Tumor Susceptibility and Alters Tumor Phenotype in Rats

(2010) Tiffany A. Polanco et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Mother counts: How effects of environmental contaminants on maternal care could affect the offspring and future generations

(2010) J.A. Cummings et al.   FRONTIERS IN NEUROENDOCRINOLOGY

Epigenetic transgenerational actions of environmental factors in disease etiology

(2010) Michael K. Skinner et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Histone lysine methylation: an epigenetic modification?

(2010) Neil P Blackledge et al.   Epigenomics

β-Endorphin Neuronal Cell Transplant Reduces Corticotropin Releasing Hormone Hyperresponse to Lipopolysaccharide and Eliminates Natural Killer Cell Functional Deficiencies in Fetal Alcohol Exposed Rats

(2009) Nadka I. Boyadjieva et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Role of Various Neurotransmitters in Mediating the Long-Term Endocrine Consequences of Prenatal Alcohol Exposure

(2009) Soon Lee et al.   Annals of the New York Academy of Sciences

H2A.Z and H3.3 Histone Variants Affect Nucleosome Structure: Biochemical and Biophysical Studies

(2009) Amit Thakar et al.   BIOCHEMISTRY

Fetal Alcohol Spectrum Disorders: The Epigenetic Perspective1

(2009) Philip C. Haycock   BIOLOGY OF REPRODUCTION

Neuroscience of alcoholism: molecular and cellular mechanisms

(2009) Sachin Moonat et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Prenatal alcohol exposure: Implications for cardiovascular function in the fetus and beyond

(2009) Helena C Parkington et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Prenatal alcohol exposure: Fetal programming and later life vulnerability to stress, depression and anxiety disorders

(2009) Kim G.C. Hellemans et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

The Nuclear DNA Base 5-Hydroxymethylcytosine Is Present in Purkinje Neurons and the Brain

(2009) S. Kriaucionis et al.   SCIENCE

Ethanol Induces Apoptotic Death of β-Endorphin Neurons in the Rat Hypothalamus by a TGF-β1-Dependent Mechanism

(2008) Peter Kuhn et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Brain Chromatin Remodeling: A Novel Mechanism of Alcoholism

(2008) S. C. Pandey et al.   JOURNAL OF NEUROSCIENCE

DNA methylation landscapes: provocative insights from epigenomics

(2008) Miho M. Suzuki et al.   NATURE REVIEWS GENETICS