Trichostatin A decreases the levels of MeCP2 expression and phosphorylation and increases its chromatin binding affinity

Dynamics of post-translationally modified histones during barley pollen embryogenesis in the presence or absence of the epi-drug trichostatin A

(2017) Pooja Pandey et al.   Plant Reproduction

A trichostatin A expression signature identified by TempO-Seq targeted whole transcriptome profiling

(2017) Joanne M. Yeakley et al.   PLoS One

Histone deacetylase inhibitors for cancer therapy: An evolutionarily ancient resistance response may explain their limited success

(2016) John A. Halsall et al.   BIOESSAYS

Rett Syndrome and the Ongoing Legacy of Close Clinical Observation

(2016) Huda Y. Zoghbi   CELL

Histone Deacetylase (HDAC) Inhibitors - emerging roles in neuronal memory, learning, synaptic plasticity and neural regeneration

(2016) Shabir Ahmad Ganai et al.   Current Neuropharmacology

Epigenetic Determinants of Cancer

(2016) Stephen B. Baylin et al.   Cold Spring Harbor Perspectives in Biology

HDACs and HDAC Inhibitors in Cancer Development and Therapy

(2016) Yixuan Li et al.   Cold Spring Harbor Perspectives in Medicine

MeCP2 and the enigmatic organization of brain chromatin. Implications for depression and cocaine addiction

(2016) Juan Ausió   Clinical Epigenetics

Brain phosphorylation of MeCP2 at serine 164 is developmentally regulated and globally alters its chromatin association

(2016) Gilda Stefanelli et al.   Scientific Reports

Disruption of DNA-methylation-dependent long gene repression in Rett syndrome

(2015) Harrison W. Gabel et al.   NATURE

Intra- and inter-nucleosomal interactions of the histone H4 tail revealed with a human nucleosome core particle with genetically-incorporated H4 tetra-acetylation

(2015) Masatoshi Wakamori et al.   Scientific Reports

Post-Translational Modifications of Histones in Vertebrate Neurogenesis

(2015) Nikolaos Mitrousis et al.   Frontiers in Neuroscience

Trend of Histone Deacetylase Inhibitors in Cancer Therapy: Isoform Selectivity or Multitargeted Strategy

(2014) Lei Zhang et al.   MEDICINAL RESEARCH REVIEWS

Histone deacetylases and their inhibitors in cancer, neurological diseases and immune disorders

(2014) Katrina J. Falkenberg et al.   NATURE REVIEWS DRUG DISCOVERY

Histone deacetylases in memory and cognition

(2014) J. Penney et al.   Science Signaling

MeCP2: the long trip from a chromatin protein to neurological disorders

(2014) Juan Ausió et al.   TRENDS IN MOLECULAR MEDICINE

MeCP2 post-translational modifications: a mechanism to control its involvement in synaptic plasticity and homeostasis?

(2014) Elisa Bellini et al.   Frontiers in Cellular Neuroscience

The promise and failures of epigenetic therapies for cancer treatment

(2013) Pasano Bojang et al.   CANCER TREATMENT REVIEWS

Impaired in vivo binding of MeCP2 to chromatin in the absence of its DNA methyl-binding domain

(2013) D. P. Stuss et al.   NUCLEIC ACIDS RESEARCH

miR-132/212 Knockout Mice Reveal Roles for These miRNAs in Regulating Cortical Synaptic Transmission and Plasticity

(2013) Judit Remenyi et al.   PLoS One

Targeting class I histone deacetylases in cancer therapy

(2012) Geneviève P Delcuve et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Nuclear Calcium Signaling Controls Methyl-CpG-binding Protein 2 (MeCP2) Phosphorylation on Serine 421 following Synaptic Activity

(2012) Bettina Buchthal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MeCP2: only 100% will do

(2012) Hsiao-Tuan Chao et al.   NATURE NEUROSCIENCE

HDAC inhibitors in cancer biology: emerging mechanisms and clinical applications

(2011) Omar Khan et al.   IMMUNOLOGY AND CELL BIOLOGY

Genome-Wide Activity-Dependent MeCP2 Phosphorylation Regulates Nervous System Development and Function

(2011) Sonia Cohen et al.   NEURON

Nucleosomes protect DNA from DNA methylation in vivo and in vitro

(2011) Max Felle et al.   NUCLEIC ACIDS RESEARCH

MeCP2 binds to nucleosome free (linker DNA) regions and to H3K9/H3K27 methylated nucleosomes in the brain

(2011) Anita A. Thambirajah et al.   NUCLEIC ACIDS RESEARCH

Epigenetic Regulation of Thy-1 by Histone Deacetylase Inhibitor in Rat Lung Fibroblasts

(2010) Yan Y. Sanders et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Identification of type-specific anticancer histone deacetylase inhibitors: road to success

(2010) Nighat Noureen et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

MeCP2 Binds Cooperatively to Its Substrate and Competes with Histone H1 for Chromatin Binding Sites

(2010) R. P. Ghosh et al.   MOLECULAR AND CELLULAR BIOLOGY

Neuronal MeCP2 Is Expressed at Near Histone-Octamer Levels and Globally Alters the Chromatin State

(2010) Peter J. Skene et al.   MOLECULAR CELL

Striatal microRNA controls cocaine intake through CREB signalling

(2010) Jonathan A. Hollander et al.   NATURE

MeCP2 and drug addiction

(2010) Jian Feng et al.   NATURE NEUROSCIENCE

MeCP2 controls BDNF expression and cocaine intake through homeostatic interactions with microRNA-212

(2010) Heh-In Im et al.   NATURE NEUROSCIENCE

Chromatin methylation activity of Dnmt3a and Dnmt3a/3L is guided by interaction of the ADD domain with the histone H3 tail

(2010) Yingying Zhang et al.   NUCLEIC ACIDS RESEARCH

Targeting the correct HDAC(s) to treat cognitive disorders

(2010) André Fischer et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Acetylation of Vertebrate H2A.Z and Its Effect on the Structure of the Nucleosome

(2009) Toyotaka Ishibashi et al.   BIOCHEMISTRY

A moment’s pause: putative nucleosome-based influences on MeCP2 regulationThis paper is one of a selection of papers published in this Special Issue, entitled 30th Annual International Asilomar Chromatin and Chromosomes Conference, and has undergone the Journal’s usual peer review process.

(2009) Anita A. Thambirajah et al.   Biochemistry and Cell Biology

Molecular dynamics of histone H1This paper is one of a selection of papers published in this Special Issue, entitled CSBMCB’s 51st Annual Meeting – Epigenetics and Chromatin Dynamics, and has undergone the Journal’s usual peer review process.

(2009) Nikhil Raghuram et al.   Biochemistry and Cell Biology

Methyl-CpG-binding protein 2 is phosphorylated by homeodomain-interacting protein kinase 2 and contributes to apoptosis

(2009) Giorgia Bracaglia et al.   EMBO REPORTS

Cocaine self-administration alters the expression of chromatin-remodelling proteins; modulation by histone deacetylase inhibition

(2009) Lionel Host et al.   JOURNAL OF PSYCHOPHARMACOLOGY

The yin and yang of MeCP2 phosphorylation

(2009) H.-T. Chao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phosphorylation of MeCP2 at Serine 80 regulates its chromatin association and neurological function

(2009) J. Tao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multiple roles of HDAC inhibition in neurodegenerative conditions

(2009) De-Maw Chuang et al.   TRENDS IN NEUROSCIENCES

Histone Deacetylase Inhibitors: Therapeutic Agents and Research Tools for Deciphering Motor Neuron Diseases

(2008) A. Echaniz-Laguna et al.   CURRENT MEDICINAL CHEMISTRY

MeCP2 preferentially binds to methylated linker DNA in the absence of the terminal tail of histone H3 and independently of histone acetylation

(2008) Toyotaka Ishibashi et al.   FEBS LETTERS

Global histone acetylation induces functional genomic reorganization at mammalian nuclear pore complexes

(2008) C. R. Brown et al.   GENES & DEVELOPMENT

Analysis of protein domains and Rett syndrome mutations indicate that multiple regions influence chromatin-binding dynamics of the chromatin-associated protein MECP2 in vivo

(2008) A. Kumar et al.   JOURNAL OF CELL SCIENCE

MeCP2, a Key Contributor to Neurological Disease, Activates and Represses Transcription

(2008) M. Chahrour et al.   SCIENCE