Simple monitoring of cell leakiness and viability in Escherichia coli bioprocesses-A case study

Multi-parameter flow cytometry as a process analytical technology (PAT) approach for the assessment of bacterial ghost production

(2015) Timo Langemann et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Production of Biopharmaceuticals in E. coli: Current Scenario and Future Perspectives

(2015) Mohammed N. Baeshen et al.   JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY

Understanding Pharmaceutical Quality by Design

(2014) Lawrence X. Yu et al.   AAPS Journal

Latest approaches for efficient protein production in drug discovery

(2014) Toshihiko Sugiki et al.   Expert Opinion on Drug Discovery

The Sec translocon mediated protein transport in prokaryotes and eukaryotes

(2014) Kärt Denks et al.   MOLECULAR MEMBRANE BIOLOGY

Biopharmaceutical benchmarks 2014

(2014) Gary Walsh   NATURE BIOTECHNOLOGY

Recombinant protein expression in Escherichia coli: advances and challenges

(2014) Germán L. Rosano et al.   Frontiers in Microbiology

Tunable recombinant protein expression with E. coli in a mixed-feed environment

(2013) Patrick Sagmeister et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Folding mechanisms of periplasmic proteins

(2013) Camille Goemans et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

A dynamic method for the investigation of induced state metabolic capacities as a function of temperature

(2013) Patrick Sagmeister et al.   Microbial Cell Factories

Monitoring of Dynamic Microbiological Processes Using Real-Time Flow Cytometry

(2013) Markus Arnoldini et al.   PLoS One

Soft-sensor assisted dynamic investigation of mixed feed bioprocesses

(2013) Patrick Sagmeister et al.   PROCESS BIOCHEMISTRY

Strategies for the Production of Recombinant Protein in Escherichia coli

(2013) Gopal Jee Gopal et al.   PROTEIN JOURNAL

On-line multiple component analysis for efficient quantitative bioprocess development

(2012) Christian Dietzsch et al.   JOURNAL OF BIOTECHNOLOGY

Effect of culture operating conditions on succinate production in a multiphase fed-batch bioreactor using an engineered Escherichia coli strain

(2011) Jiangfeng Zhu et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Tuning different expression parameters to achieve soluble recombinant proteins in E. coli: Advantages of high-throughput screening

(2011) Agustín Correa et al.   Biotechnology Journal

Real-time on-line flow cytometry for bioprocess monitoring

(2011) Tobias Broger et al.   JOURNAL OF BIOTECHNOLOGY

Strategies for successful recombinant expression of disulfide bond-dependent proteins in Escherichia coli

(2009) Ario de Marco   Microbial Cell Factories