Unknown unknowns: essential genes in quest for function

Chemical Morphing of DNA Containing Four Noncanonical Bases

(2016) Elena Eremeeva et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A water-forming NADH oxidase regulates metabolism in anaerobic fermentation

(2016) Xin-Chi Shi et al.   Biotechnology for Biofuels

Protein aggregation as a mechanism of adaptive cellular responses

(2016) Juha Saarikangas et al.   CURRENT GENETICS

A conserved phosphatase destroys toxic glycolytic side products in mammals and yeast

(2016) François Collard et al.   Nature Chemical Biology

Design and synthesis of a minimal bacterial genome

(2016) C. A. Hutchison et al.   SCIENCE

Inorganic polyphosphate in the microbial world. Emerging roles for a multifaceted biopolymer

(2016) Tomás Albi et al.   WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY

The CRISPR Conundrum: As Millions of Dollars Flow into Developing the Gene-Editing Tool, Scientists Continue to Discover the Technology?s Potential and Pitfalls

(2016) Mary Bates   IEEE Pulse

What Is the Tree of Life?

(2016) W. Ford Doolittle et al.   PLoS Genetics

phoUInactivation in Pseudomonas aeruginosa Enhances Accumulation of ppGpp and Polyphosphate

(2015) Luiz Gustavo de Almeida et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Evolution and Functional Diversity of Aquaporins

(2015) Roderick Nigel Finn et al.   BIOLOGICAL BULLETIN

Catalysis of an Essential Step in Vitamin B2Biosynthesis by a Consortium of Broad Spectrum Hydrolases

(2015) Sonja Sarge et al.   CHEMBIOCHEM

Mechanisms of mechanosensing — mechanosensitive channels, function and re-engineering

(2015) Armagan Kocer   CURRENT OPINION IN CHEMICAL BIOLOGY

Pseudomonas putidaKT2440 Strain Metabolizes Glucose through a Cycle Formed by Enzymes of the Entner-Doudoroff, Embden-Meyerhof-Parnas, and Pentose Phosphate Pathways

(2015) Pablo I. Nikel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Specificity and Evolutionary Conservation of theEscherichia coliRNA Pyrophosphohydrolase RppH

(2015) Patricia L. Foley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Exploring the Existence of Lipid Rafts in Bacteria

(2015) Marc Bramkamp et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Cyclic Rhamnosylated Elongation Factor P Establishes Antibiotic Resistance in Pseudomonas aeruginosa

(2015) Andrei Rajkovic et al.   mBio

High-Precision Analysis of Translational Pausing by Ribosome Profiling in Bacteria Lacking EFP

(2015) Christopher J. Woolstenhulme et al.   Cell Reports

Secretion of Bacterial Lipoproteins: Through the Cytoplasmic Membrane, the Periplasm and Beyond

(2014) Wolfram R. Zückert   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

YlxM Is a Newly Identified Accessory Protein That Influences the Function of Signal Recognition Particle Pathway Components in Streptococcus mutans

(2014) M. L. Williams et al.   JOURNAL OF BACTERIOLOGY

Specific N-terminal cleavage of ribosomal protein L27 inStaphylococcus aureusand related bacteria

(2014) Erin A. Wall et al.   MOLECULAR MICROBIOLOGY

The ABC-F protein EttA gates ribosome entry into the translation elongation cycle

(2014) Grégory Boël et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The flavoprotein Mcap0476 (RlmFO) catalyzes m5U1939 modification inMycoplasma capricolum23S rRNA

(2014) Carole Lartigue et al.   NUCLEIC ACIDS RESEARCH

Predicting the Minimal Translation Apparatus: Lessons from the Reductive Evolution of Mollicutes

(2014) Henri Grosjean et al.   PLoS Genetics

The logic of metabolism and its fuzzy consequences

(2013) Antoine Danchin et al.   ENVIRONMENTAL MICROBIOLOGY

Methylglyoxal resistance inBacillus subtilis: contributions of bacillithiol-dependent and independent pathways

(2013) Pete Chandrangsu et al.   MOLECULAR MICROBIOLOGY

Crystal structure of a folate energy-coupling factor transporter from Lactobacillus brevis

(2013) Ke Xu et al.   NATURE

Comprehensive analysis of DNA polymerase III α subunits and their homologs in bacterial genomes

(2013) Kęstutis Timinskas et al.   NUCLEIC ACIDS RESEARCH

REXO2 Is an Oligoribonuclease Active in Human Mitochondria

(2013) Francesco Bruni et al.   PLoS One

Bacillus subtilis RNA deprotection enzyme RppH recognizes guanosine in the second position of its substrates

(2013) J. Piton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Manganese Complexes: Diverse Metabolic Routes to Oxidative Stress Resistance in Prokaryotes and Yeast

(2012) Valeria C. Culotta et al.   ANTIOXIDANTS & REDOX SIGNALING

Osmoprotection of Bacillus subtilis through Import and Proteolysis of Proline-Containing Peptides

(2012) Adrienne Zaprasis et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Distinct co-evolution patterns of genes associated to DNA polymerase III DnaE and PolC

(2012) Stefan Engelen et al.   BMC GENOMICS

YbxF and YlxQ are bacterial homologs of L7Ae and bind K-turns but not K-loops

(2012) N. J. Baird et al.   RNA

From essential to persistent genes: a functional approach to constructing synthetic life

(2012) Carlos G. Acevedo-Rocha et al.   TRENDS IN GENETICS

Exploring potassium-dependent GTP hydrolysis in TEES family GTPases

(2012) Abu Rafay et al.   FEBS Open Bio

Chemical Evolution of a Bacterium’s Genome

(2011) Philippe Marlière et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Life's demons: information and order in biology

(2011) Philippe M Binder et al.   EMBO REPORTS

CodY-Mediated Regulation of Guanosine Uptake in Bacillus subtilis

(2011) Boris R. Belitsky et al.   JOURNAL OF BACTERIOLOGY

Characterization of NrnA homologs from Mycobacterium tuberculosis and Mycoplasma pneumoniae

(2011) G. Postic et al.   RNA

Inorganic pyrophosphatase in uncultivable hemotrophic mycoplasmas: identification and properties of the enzyme from Mycoplasma suis

(2010) Katharina Hoelzle et al.   BMC MICROBIOLOGY

tRNA biology charges to the front

(2010) E. M. Phizicky et al.   GENES & DEVELOPMENT

Inorganic Polyphosphate: Essential for Growth and Survival

(2009) Narayana N. Rao et al.   Annual Review of Biochemistry

Cells need safety valves

(2009) Antoine Danchin   BIOESSAYS

Isoaspartate residues dramatically influence substrate recognition and turnover by proteases

(2008) Livia Böhme et al.   BIOLOGICAL CHEMISTRY

Synthetic biology: discovering new worlds and new words. The new and not so new aspects of this emerging research field

(2008) Víctor de Lorenzo et al.   EMBO REPORTS

Competitive inhibition of phosphoglucose isomerase of apple leaves by sorbitol 6-phosphate

(2008) Rui Zhou et al.   JOURNAL OF PLANT PHYSIOLOGY

Evolving genetic code

(2008) Takeshi OHAMA et al.   PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES