Functional Roles of E6 and E7 Oncoproteins in HPV-Induced Malignancies at Diverse Anatomical Sites

Molecular mechanisms underlying human papillomavirus E6 and E7 oncoprotein-induced cell transformation

(2017) Suruchi Mittal et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Analysis of Multiple HPV E6 PDZ Interactions Defines Type-Specific PDZ Fingerprints That Predict Oncogenic Potential

(2016) Miranda Thomas et al.   PLoS Pathogens

HPV Positive Head and Neck Cancers: Molecular Pathogenesis and Evolving Treatment Strategies

(2016) Rüveyda Dok et al.   Cancers

Carcinogenic HPV infection in the cervical squamo-columnar junction

(2015) Jelena Mirkovic et al.   JOURNAL OF PATHOLOGY

Model systems of human papillomavirus-associated disease

(2015) John Doorbar   JOURNAL OF PATHOLOGY

Do high-risk human papillomaviruses cause oral cavity squamous cell carcinoma?

(2015) H. Mirghani et al.   ORAL ONCOLOGY

Human papillomavirus molecular biology and disease association

(2015) John Doorbar et al.   REVIEWS IN MEDICAL VIROLOGY

Beta genus papillomaviruses and skin cancer

(2015) Peter M. Howley et al.   VIROLOGY

The Human Papillomavirus E6 PDZ Binding Motif: From Life Cycle to Malignancy

(2015) Ketaki Ganti et al.   Viruses-Basel

Human Papillomaviruses; Epithelial Tropisms, and the Development of Neoplasia

(2015) Nagayasu Egawa et al.   Viruses-Basel

HPV and cancer of the oral cavity

(2015) Christian U Hübbers et al.   Virulence

Human papillomaviruses: shared and distinct pathways for pathogenesis

(2015) Denise A Galloway et al.   Current Opinion in Virology

Current trends in the etiology and diagnosis of HPV-related head and neck cancers

(2015) Ryan C. Chai et al.   Cancer Medicine

Novel Functions of the Human Papillomavirus E6 Oncoproteins

(2015) Nicholas A. Wallace et al.   Annual Review of Virology

Model systems to study the life cycle of human papillomaviruses and HPV-associated cancers

(2015) Louise T. Chow   VIROLOGICA SINICA

Prevalence of Human Papillomavirus in Cancer of the Oropharynx by Gender

(2014) J.-D. Combes et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Resistance to UV-induced apoptosis by β-HPV5 E6 involves targeting of activated BAK for proteolysis by recruitment of the HERC1 ubiquitin ligase

(2014) Amy Holloway et al.   INTERNATIONAL JOURNAL OF CANCER

Mate pair sequencing of oropharyngeal squamous cell carcinomas reveals that HPV integration occurs much less frequently than in cervical cancer

(2014) Ge Gao et al.   JOURNAL OF CLINICAL VIROLOGY

The Viral Etiology of Skin Cancer

(2014) Jordan M. Meyers et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

HumanBeta-papillomavirusinfection and keratinocyte carcinomas

(2014) Koen D Quint et al.   JOURNAL OF PATHOLOGY

Cancer-Causing Human Papillomavirus E6 Proteins Display Major Differences in the Phospho-Regulation of Their PDZ Interactions

(2014) Siaw Shi Boon et al.   JOURNAL OF VIROLOGY

Human Papillomavirus Induced Transformation in Cervical and Head and Neck Cancers

(2014) Allie Adams et al.   Cancers

Evaluation of Human Papillomavirus Antibodies and Risk of Subsequent Head and Neck Cancer

(2013) Aimée R. Kreimer et al.   JOURNAL OF CLINICAL ONCOLOGY

Worldwide Trends in Incidence Rates for Oral Cavity and Oropharyngeal Cancers

(2013) Anil K. Chaturvedi et al.   JOURNAL OF CLINICAL ONCOLOGY

The Human Papillomavirus Type 8 E6 Protein Interferes with NOTCH Activation during Keratinocyte Differentiation

(2013) J. M. Meyers et al.   JOURNAL OF VIROLOGY

Oncoprotein E7 from Beta Human Papillomavirus 38 Induces Formation of an Inhibitory Complex for a Subset of p53-Regulated Promoters

(2013) D. Saidj et al.   JOURNAL OF VIROLOGY

The Role of Protein Kinase A Regulation of the E6 PDZ-Binding Domain during the Differentiation-Dependent Life Cycle of Human Papillomavirus Type 18

(2013) C. P. Delury et al.   JOURNAL OF VIROLOGY

Structural Basis for Hijacking of Cellular LxxLL Motifs by Papillomavirus E6 Oncoproteins

(2013) K. Zanier et al.   SCIENCE

The human papillomavirus family and its role in carcinogenesis

(2013) Massimo Tommasino   SEMINARS IN CANCER BIOLOGY

Interaction of HPV E6 oncoproteins with specific proteasomal subunits

(2013) Vjekoslav Tomaić et al.   VIROLOGY

Human papillomaviruses and the specificity of PDZ domain targeting

(2012) David Pim et al.   FEBS Journal

A novel blueprint for ‘top down’ differentiation defines the cervical squamocolumnar junction during development, reproductive life, and neoplasia

(2012) Michael Herfs et al.   JOURNAL OF PATHOLOGY

Comprehensive Analysis of Host Cellular Interactions with Human Papillomavirus E6 Proteins Identifies New E6 Binding Partners and Reflects Viral Diversity

(2012) E. A. White et al.   JOURNAL OF VIROLOGY

High-Risk Human Papillomavirus E6 Oncoproteins Interact with 14-3-3ζ in a PDZ Binding Motif-Dependent Manner

(2012) Siaw Shi Boon et al.   JOURNAL OF VIROLOGY

Reconstruction of Human Papillomavirus Type 16-Mediated Early-Stage Neoplasia Implicates E6/E7 Deregulation and the Loss of Contact Inhibition in Neoplastic Progression

(2012) E. Isaacson Wechsler et al.   JOURNAL OF VIROLOGY

Cutaneous papillomavirus E6 oncoproteins associate with MAML1 to repress transactivation and NOTCH signaling

(2012) N Brimer et al.   ONCOGENE

E4 Antibodies Facilitate Detection and Type-Assignment of Active HPV Infection in Cervical Disease

(2012) Heather Griffin et al.   PLoS One

The Biology and Life-Cycle of Human Papillomaviruses

(2012) John Doorbar et al.   VACCINE

Interactions between E6AP and E6 proteins from alpha and beta HPV types

(2012) Miranda Thomas et al.   VIROLOGY

HPV 5 and 8 E6 Abrogate ATR Activity Resulting in Increased Persistence of UVB Induced DNA Damage

(2012) Nicholas A. Wallace et al.   PLoS Pathogens

Comparative Analysis of Transforming Properties of E6 and E7 from Different Beta Human Papillomavirus Types

(2011) I. Cornet et al.   JOURNAL OF VIROLOGY

Regulation of the Human Papillomavirus Type 18 E6/E6AP Ubiquitin Ligase Complex by the HECT Domain-Containing Protein EDD

(2011) V. Tomaic et al.   JOURNAL OF VIROLOGY

I B Kinase   Promotes Cell Survival by Antagonizing p53 Functions through  Np73  Phosphorylation and Stabilization

(2011) R. Accardi et al.   MOLECULAR AND CELLULAR BIOLOGY

Cutaneous HPV23 E6 Prevents p53 Phosphorylation through Interaction with HIPK2

(2011) Dorothea Muschik et al.   PLoS One

Human papillomavirus genotype distribution in tonsil cancers

(2011) Jean St Guily et al.   Head and Neck Optical Diagnostics Society

E6 and E7 from Beta Hpv38 Cooperate with Ultraviolet Light in the Development of Actinic Keratosis-Like Lesions and Squamous Cell Carcinoma in Mice

(2011) Daniele Viarisio et al.   PLoS Pathogens

Interaction of viral oncoproteins with cellular target molecules: infection with high-risk vs low-risk human papillomaviruses

(2010) DAVID PIM et al.   APMIS

Anal cancer and cervical cancer screening: Key differences

(2010) Teresa M. Darragh et al.   CANCER CYTOPATHOLOGY

Cutaneous Papillomavirus E6 Proteins Must Interact with p300 and Block p53-Mediated Apoptosis for Cellular Immortalization and Tumorigenesis

(2010) P. Muench et al.   CANCER RESEARCH

Classification of papillomaviruses (PVs) based on 189 PV types and proposal of taxonomic amendments

(2010) Hans-Ulrich Bernard et al.   VIROLOGY

Distribution Pattern and Marker Profile Show Two Subpopulations of Reserve Cells in the Endocervical Canal

(2009) Jolise E. Martens et al.   INTERNATIONAL JOURNAL OF GYNECOLOGICAL PATHOLOGY

E6 Proteins from Diverse Papillomaviruses Self-Associate Both In Vitro and In Vivo

(2009) Katia Zanier et al.   JOURNAL OF MOLECULAR BIOLOGY

The Ubiquitin-Specific Peptidase USP15 Regulates Human Papillomavirus Type 16 E6 Protein Stability

(2009) R. M. Vos et al.   JOURNAL OF VIROLOGY

A review of human carcinogens—Part B: biological agents

(2009) Véronique Bouvard et al.   LANCET ONCOLOGY

The EVER Proteins as a Natural Barrier against Papillomaviruses: a New Insight into the Pathogenesis of Human Papillomavirus Infections

(2009) M. Lazarczyk et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

The stability of the human papillomavirus E6 oncoprotein is E6AP dependent

(2009) Vjekoslav Tomaić et al.   VIROLOGY

Cell-type specific transcriptional activities among different papillomavirus long control regions and their regulation by E2

(2009) Matthias Ottinger et al.   VIROLOGY

Deregulation of Scribble Promotes Mammary Tumorigenesis and Reveals a Role for Cell Polarity in Carcinoma

(2008) Lixing Zhan et al.   CELL

E6 Proteins from Multiple Human Betapapillomavirus Types Degrade Bak and Protect Keratinocytes from Apoptosis after UVB Irradiation

(2008) M. P. Underbrink et al.   JOURNAL OF VIROLOGY

The E6 Oncoproteins from Human Betapapillomaviruses Differentially Activate Telomerase through an E6AP-Dependent Mechanism and Prolong the Lifespan of Primary Keratinocytes

(2008) K. M. Bedard et al.   JOURNAL OF VIROLOGY

Human Papillomavirus Type 16 E7 Oncoprotein Associates with E2F6

(2008) M. E. McLaughlin-Drubin et al.   JOURNAL OF VIROLOGY

NFX1 Interacts with mSin3A/Histone Deacetylase To Repress hTERT Transcription in Keratinocytes

(2008) M. Xu et al.   MOLECULAR AND CELLULAR BIOLOGY

Human and primate tumour viruses use PDZ binding as an evolutionarily conserved mechanism of targeting cell polarity regulators

(2008) V Tomaić et al.   ONCOGENE

Cell polarity proteins: common targets for tumorigenic human viruses

(2008) R T Javier   ONCOGENE

Human papillomaviruses, cervical cancer and cell polarity

(2008) M Thomas et al.   ONCOGENE

Oropharyngeal carcinoma in non-smokers and non-drinkers: A role for HPV

(2008) Elizabeth Andrews et al.   ORAL ONCOLOGY

Impairment of the telomere/telomerase system and genomic instability are associated with keratinocyte immortalization induced by the skin human papillomavirus type 38

(2007) Anne-Sophie Gabet et al.   FASEB JOURNAL