Resistance to UV-induced apoptosis by β-HPV5 E6 involves targeting of activated BAK for proteolysis by recruitment of the HERC1 ubiquitin ligase

Human Papillomavirus Load in Eyebrow Hair Follicles and Risk of Cutaneous Squamous Cell Carcinoma

(2013) R. E. Neale et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

BAK multimerization for apoptosis, but not bid binding, is inhibited by negatively charged residue in the BAK hydrophobic groove

(2013) Abul Azad et al.   Molecular Cancer

Blockade of the BAK Hydrophobic Groove by Inhibitory Phosphorylation Regulates Commitment to Apoptosis

(2012) Abul Azad et al.   PLoS One

Physical and Functional Interaction of the HECT Ubiquitin-protein Ligases E6AP and HERC2

(2011) Simone Kühnle et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of the Human Papillomavirus Type 18 E6/E6AP Ubiquitin Ligase Complex by the HECT Domain-Containing Protein EDD

(2011) V. Tomaic et al.   JOURNAL OF VIROLOGY

Beta-papillomavirus DNA loads in hair follicles of immunocompetent people and organ transplant recipients

(2011) Sönke Weissenborn et al.   MEDICAL MICROBIOLOGY AND IMMUNOLOGY

Cutaneous HPV5 E6 causes increased expression of Osteoprotegerin and Interleukin 6 which contribute to evasion of UV-induced apoptosis

(2010) Christine Tomlins et al.   CARCINOGENESIS

Bcl-2 family interaction with the mitochondrial morphogenesis machinery

(2010) M M Cleland et al.   CELL DEATH AND DIFFERENTIATION

Tyrosine dephosphorylation is required for Bak activation in apoptosis

(2010) Joanna L Fox et al.   EMBO JOURNAL

Bax activation by the BH3-only protein Puma promotes cell dependence on antiapoptotic Bcl-2 family members

(2009) Tristan Gallenne et al.   JOURNAL OF CELL BIOLOGY

Spontaneous tumour development in human papillomavirus type 8 E6 transgenic mice and rapid induction by UV-light exposure and wounding

(2009) G. P. Marcuzzi et al.   JOURNAL OF GENERAL VIROLOGY

Bak Activation for Apoptosis Involves Oligomerization of Dimers via Their α6 Helices

(2009) Grant Dewson et al.   MOLECULAR CELL

Identification of the regions of the HPV 5 E6 protein involved in Bak degradation and inhibition of apoptosis

(2008) Mark Simmonds et al.   INTERNATIONAL JOURNAL OF CANCER

Oligomerization of BAK by p53 Utilizes Conserved Residues of the p53 DNA Binding Domain

(2008) E. Christine Pietsch et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Detection of Human Papillomavirus DNA in Cutaneous Squamous Cell Carcinoma among Immunocompetent Individuals

(2008) Maryam M. Asgari et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

E6 Proteins from Multiple Human Betapapillomavirus Types Degrade Bak and Protect Keratinocytes from Apoptosis after UVB Irradiation

(2008) M. P. Underbrink et al.   JOURNAL OF VIROLOGY

The E6 Oncoproteins from Human Betapapillomaviruses Differentially Activate Telomerase through an E6AP-Dependent Mechanism and Prolong the Lifespan of Primary Keratinocytes

(2008) K. M. Bedard et al.   JOURNAL OF VIROLOGY

To Trigger Apoptosis, Bak Exposes Its BH3 Domain and Homodimerizes via BH3:Groove Interactions

(2008) Grant Dewson et al.   MOLECULAR CELL

Mechanism of apoptosis induction by inhibition of the anti-apoptotic BCL-2 proteins

(2008) J. E. Chipuk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The BCL-2 protein family: opposing activities that mediate cell death

(2007) Richard J. Youle et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY