Revisiting rodent models: Octodon degus as Alzheimer’s disease model?

Animal Models of the Sporadic Form of Alzheimer's Disease: Focus on the Disease and Not Just the Lesions1

(2018) Khalid Iqbal et al.   JOURNAL OF ALZHEIMERS DISEASE

Immunohistochemical Visualization of Amyloid-β Protein Precursor and Amyloid-β in Extra- and Intracellular Compartments in the Human Brain

(2017) Leena Aho et al.   JOURNAL OF ALZHEIMERS DISEASE

Molecular Mechanisms of Amyloid Oligomers Toxicity

(2016) Rakez Kayed et al.   JOURNAL OF ALZHEIMERS DISEASE

Amyloid-β dimers in the absence of plaque pathology impair learning and synaptic plasticity

(2015) Andreas Müller-Schiffmann et al.   BRAIN

Age Progression of Neuropathological Markers in the Brain of the Chilean RodentOctodon degus, a Natural Model of Alzheimer's Disease

(2015) Nibaldo C. Inestrosa et al.   BRAIN PATHOLOGY

Natural AD-Like Neuropathology in Octodon degus: Impaired Burrowing and Neuroinflammation

(2015) Robert Deacon et al.   Current Alzheimer Research

Accelerating Alzheimerʼs research through ‘natural’ animal models

(2015) Nady Braidy et al.   CURRENT OPINION IN PSYCHIATRY

Activation of Mitochondrial Complex II-Dependent Respiration Is Beneficial for α-Synucleinopathies

(2015) Christina Fröhlich et al.   MOLECULAR NEUROBIOLOGY

Role of F3/contactin expression profile in synaptic plasticity and memory in aged mice

(2015) Daniela Puzzo et al.   NEUROBIOLOGY OF AGING

Sustained high levels of neuroprotective, high molecular weight, phosphorylated tau in the longest-lived rodent

(2015) Miranda E. Orr et al.   NEUROBIOLOGY OF AGING

Cerebral ABC Transporter-common Mechanisms May Modulate Neurodegenerative Diseases and Depression in Elderly Subjects

(2014) Jens Pahnke et al.   ARCHIVES OF MEDICAL RESEARCH

Alzheimer disease: Epidemiology, diagnostic criteria, risk factors and biomarkers

(2014) Christiane Reitz et al.   BIOCHEMICAL PHARMACOLOGY

CXCR3 promotes plaque formation and behavioral deficits in an Alzheimer’s disease model

(2014) Marius Krauthausen et al.   JOURNAL OF CLINICAL INVESTIGATION

A three-dimensional human neural cell culture model of Alzheimer’s disease

(2014) Se Hoon Choi et al.   NATURE

Is Alzheimer's disease related to metabolic syndrome? A Wnt signaling conundrum

(2014) Juvenal A. Ríos et al.   PROGRESS IN NEUROBIOLOGY

Role of connexin channels in the retinal light response of a diurnal rodent

(2014) Angelina Palacios-Muñoz et al.   Frontiers in Cellular Neuroscience

Octodon degus: A Model for the Cognitive Impairment Associated with Alzheimer's Disease

(2013) Ernesto Tarragon et al.   CNS Neuroscience & Therapeutics

Fecal cortisol levels predict breeding but not survival of females in the short-lived rodent, Octodon degus

(2013) Luis A. Ebensperger et al.   GENERAL AND COMPARATIVE ENDOCRINOLOGY

Oxidative damage and amyloid-β metabolism in brain regions of the longest-lived rodents

(2013) Yael H. Edrey et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Amyloid beta and the longest-lived rodent: the naked mole-rat as a model for natural protection from Alzheimer's disease

(2013) Yael H. Edrey et al.   NEUROBIOLOGY OF AGING

Aging, cortical injury and Alzheimer's disease-like pathology in the guinea pig brain

(2013) Kristyn Bates et al.   NEUROBIOLOGY OF AGING

Long-Term Treatment of Thalidomide Ameliorates Amyloid-Like Pathology through Inhibition of β-Secretase in a Mouse Model of Alzheimer’s Disease

(2013) Ping He et al.   PLoS One

Three-dimensional reconstruction of brain structures of the rodent Octodon degus: a brain atlas constructed by combining histological and magnetic resonance images

(2013) Noriko Kumazawa-Manita et al.   EXPERIMENTAL BRAIN RESEARCH

The genetics and neuropathology of Alzheimer’s disease

(2012) Gerard D. Schellenberg et al.   ACTA NEUROPATHOLOGICA

Inhibition of phosphodiesterase-5 rescues age-related impairment of synaptic plasticity and memory

(2012) Agostino Palmeri et al.   BEHAVIOURAL BRAIN RESEARCH

Alzheimer’s Disease Amyloid β-Protein Mutations and Deletions That Define Neuronal Binding/Internalization as Early Stage Nonfibrillar/Fibrillar Aggregates and Late Stage Fibrils

(2012) Joseph F. Poduslo et al.   BIOCHEMISTRY

ABC Transporters B1, C1 and G2 Differentially Regulate Neuroregeneration in Mice

(2012) Toni Schumacher et al.   PLoS One

Postsynaptic dysfunction is associated with spatial and object recognition memory loss in a natural model of Alzheimer's disease

(2012) A. O. Ardiles et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cerebral amyloid-β proteostasis is regulated by the membrane transport protein ABCC1 in mice

(2011) Markus Krohn et al.   JOURNAL OF CLINICAL INVESTIGATION

Recent rodent models for Alzheimer’s disease: clinical implications and basic research

(2011) Nady Braidy et al.   JOURNAL OF NEURAL TRANSMISSION

Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

(2011) Paul Hollingworth et al.   NATURE GENETICS

Rapid Changes in Phospho-MAP/Tau Epitopes during Neuronal Stress: Cofilin-Actin Rods Primarily Recruit Microtubule Binding Domain Epitopes

(2011) Ineka T. Whiteman et al.   PLoS One

Presenilin-2 Mutation Causes Early Amyloid Accumulation and Memory Impairment in a Transgenic Mouse Model of Alzheimer's Disease

(2010) Toshihiko Toda et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

LRP1 mediates bidirectional transcytosis of amyloid-β across the blood-brain barrier

(2010) Thorsten Pflanzner et al.   NEUROBIOLOGY OF AGING

Copper Enhances Amyloid-β Peptide Neurotoxicity and non β-Aggregation: A Series of Experiments Conducted upon Copper-Bound and Copper-Free Amyloid-β Peptide

(2009) Xueling Dai et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Age-related brain pathology in Octodon degu: Blood vessel, white matter and Alzheimer-like pathology

(2009) Thomas van Groen et al.   NEUROBIOLOGY OF AGING

Long-term administration of green tea catechins prevents age-related spatial learning and memory decline in C57BL/6 J mice by regulating hippocampal cyclic amp-response element binding protein signaling cascade

(2009) Q. Li et al.   NEUROSCIENCE

Energy landscapes of the monomer and dimer of the Alzheimer’s peptide Aβ(1–28)

(2008) Xiao Dong et al.   JOURNAL OF CHEMICAL PHYSICS