CXCR3 promotes plaque formation and behavioral deficits in an Alzheimer’s disease model

Chemokine Gene Expression during Fatal Murine Cerebral Malaria and Protection Due to CXCR3 Deficiency

(2014) J. Miu et al.   JOURNAL OF IMMUNOLOGY

Neural Stem Cell Transplants Improve Cognitive Function Without Altering Amyloid Pathology in an APP/PS1 Double Transgenic Model of Alzheimer’s Disease

(2014) Wei Zhang et al.   MOLECULAR NEUROBIOLOGY

Early BDNF Treatment Ameliorates Cell Loss in the Entorhinal Cortex of APP Transgenic Mice

(2013) A. H. Nagahara et al.   JOURNAL OF NEUROSCIENCE

Fractalkine overexpression suppresses tau pathology in a mouse model of tauopathy

(2013) Kevin R. Nash et al.   NEUROBIOLOGY OF AGING

Selective Loss of Noradrenaline Exacerbates Early Cognitive Dysfunction and Synaptic Deficits in APP/PS1 Mice

(2012) Thea Hammerschmidt et al.   BIOLOGICAL PSYCHIATRY

Glial cells in (patho)physiology

(2012) Vladimir Parpura et al.   JOURNAL OF NEUROCHEMISTRY

NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice

(2012) Michael T. Heneka et al.   NATURE

Opposing Roles for CXCR3 Signaling in Central Nervous System Versus Ocular Inflammation Mediated by the Astrocyte-Targeted Production of IL-12

(2011) Marius Krauthausen et al.   AMERICAN JOURNAL OF PATHOLOGY

Targeting TNF-Alpha to Elucidate and Ameliorate Neuroinflammation in Neurodegenerative Diseases

(2011) Kathryn A. Frankola et al.   CNS & Neurological Disorders-Drug Targets

Nitration of Tyrosine 10 Critically Enhances Amyloid β Aggregation and Plaque Formation

(2011) Markus P. Kummer et al.   NEURON

CX3CR1 Deficiency Alters Microglial Activation and Reduces Beta-Amyloid Deposition in Two Alzheimer's Disease Mouse Models

(2010) Sungho Lee et al.   AMERICAN JOURNAL OF PATHOLOGY

CXCL10/CXCR3 signaling in glia cells differentially affects NMDA-induced cell death in CA and DG neurons of the mouse hippocampus

(2010) Hilmar R.J. van Weering et al.   HIPPOCAMPUS

Inflammation in neurodegenerative diseases

(2010) Sandra Amor et al.   IMMUNOLOGY

Neuroinflammatory processes in Alzheimer’s disease

(2010) Michael T. Heneka et al.   JOURNAL OF NEURAL TRANSMISSION

Fas ligation and tumor necrosis factor alpha activation of murine astrocytes promote heat shock factor-1 activation and heat shock protein expression leading to chemokine induction and cell survival

(2010) Kuicheon Choi et al.   JOURNAL OF NEUROCHEMISTRY

TNF-α-dependent regulation of CXCR3 expression modulates neuronal survival during West Nile virus encephalitis

(2010) Bo Zhang et al.   JOURNAL OF NEUROIMMUNOLOGY

CCL2 modulates cytokine production in cultured mouse astrocytes

(2010) Bridgette D Semple et al.   Journal of Neuroinflammation

Distinct modulation of microglial amyloid beta phagocytosis and migration by neuropeptides

(2010) Sigal Fleisher-Berkovich et al.   Journal of Neuroinflammation

CX3CR1 in Microglia Regulates Brain Amyloid Deposition through Selective Protofibrillar Amyloid-  Phagocytosis

(2010) Z. Liu et al.   JOURNAL OF NEUROSCIENCE

Deletion of CD14 Attenuates Alzheimer's Disease Pathology by Influencing the Brain's Inflammatory Milieu

(2010) E. G. Reed-Geaghan et al.   JOURNAL OF NEUROSCIENCE

Microglial Cx3cr1 knockout prevents neuron loss in a mouse model of Alzheimer's disease

(2010) Martin Fuhrmann et al.   NATURE NEUROSCIENCE

Review: The chemokine receptor CXCR3 and its ligands CXCL9, CXCL10 and CXCL11 in neuroimmunity - a tale of conflict and conundrum

(2010) M. Müller et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Amyloid Deposition and Inflammation in APPswe/PS1dE9 Mouse Model of Alzheimers Disease

(2009) Lingfei Ruan et al.   Current Alzheimer Research

α-secretase mediated conversion of the amyloid precursor protein derived membrane stub C99 to C83 limits Aβ generation

(2009) Sebastian Jäger et al.   JOURNAL OF NEUROCHEMISTRY

Chronic CXCL10 alters neuronal properties in rat hippocampal culture

(2009) Jungsook Cho et al.   JOURNAL OF NEUROIMMUNOLOGY

Inhibition of soluble TNF signaling in a mouse model of Alzheimer's disease prevents pre-plaque amyloid-associated neuropathology

(2009) Fiona E. McAlpine et al.   NEUROBIOLOGY OF DISEASE

CCR5 deficiency induces astrocyte activation, Aβ deposit and impaired memory function

(2009) Yong Kyoung Lee et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

CCL2 Accelerates Microglia-Mediated Aβ Oligomer Formation and Progression of Neurocognitive Dysfunction

(2009) Tomomi Kiyota et al.   PLoS One

Discovery of small molecule benzimidazole antagonists of the chemokine receptor CXCR3

(2008) Martin E. Hayes et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Cell-specific and concentration-dependent actions of interleukin-1 in acute brain inflammation

(2008) Emmanuel Pinteaux et al.   CYTOKINE

Further evidence for a crucial role of resident endoneurial macrophages in peripheral nerve disorders: Lessons from acrylamide-induced neuropathy

(2008) Marcus Müller et al.   GLIA

Expression of CXCL4 in microglia in vitro and in vivo and its possible signaling through CXCR3

(2008) Eiko K. de Jong et al.   JOURNAL OF NEUROCHEMISTRY

Accelerated Prion Replication in, but Prolonged Survival Times of, Prion-Infected CXCR3-/- Mice

(2008) C. Riemer et al.   JOURNAL OF VIROLOGY