The genetics and neuropathology of Alzheimer’s disease

Systematic Analysis of Candidate Genes for Alzheimer's Disease in a French, Genome-Wide Association Study

(2017) Geoffroy Laumet et al.   JOURNAL OF ALZHEIMERS DISEASE

The CALHM1 P86L Polymorphism is a Genetic Modifier of Age at Onset in Alzheimer's Disease: a Meta-Analysis Study

(2017) Jean-Charles Lambert et al.   JOURNAL OF ALZHEIMERS DISEASE

Expression Profiling of the Ephrin (EFN) and Eph Receptor (EPH) Family of Genes in Atherosclerosis-Related Human Cells

(2013) A Sakamoto et al.   JOURNAL OF INTERNATIONAL MEDICAL RESEARCH

Five Years of GWAS Discovery

(2012) Peter M. Visscher et al.   AMERICAN JOURNAL OF HUMAN GENETICS

ApoE-Directed Therapeutics Rapidly Clear  -Amyloid and Reverse Deficits in AD Mouse Models

(2012) P. E. Cramer et al.   SCIENCE

TDP-43 pathological changes in early onset familial and sporadic Alzheimer’s disease, late onset Alzheimer’s disease and Down’s Syndrome: association with age, hippocampal sclerosis and clinical phenotype

(2011) Yvonne S. Davidson et al.   ACTA NEUROPATHOLOGICA

Amyloid Precursor Protein Processing and Alzheimer's Disease

(2011) Richard J. O'Brien et al.   Annual Review of Neuroscience

Association and Expression Analyses With Single-Nucleotide Polymorphisms in TOMM40 in Alzheimer Disease

(2011) Carlos Cruchaga   ARCHIVES OF NEUROLOGY

Meta-analysis of the Association Between Variants in SORL1 and Alzheimer Disease

(2011) Christiane Reitz   ARCHIVES OF NEUROLOGY

Membrane shaping by the Bin/amphiphysin/Rvs (BAR) domain protein superfamily

(2011) Yijian Rao et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Apolipoprotein E isoforms and regulation of the innate immune response in brain of patients with Alzheimer's disease

(2011) C Dirk Keene et al.   CURRENT OPINION IN NEUROBIOLOGY

Complement receptor 1 (CR1) and Alzheimer's disease

(2011) Helen Crehan et al.   IMMUNOBIOLOGY

Endosomal clathrin drives actin accumulation at the immunological synapse

(2011) C. Calabia-Linares et al.   JOURNAL OF CELL SCIENCE

Mind the IGAP

(2011) David Holmes   LANCET NEUROLOGY

APOE and Alzheimer disease: a major gene with semi-dominant inheritance

(2011) E Genin et al.   MOLECULAR PSYCHIATRY

Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy

(2011) Günter U Höglinger et al.   NATURE GENETICS

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

(2011) Adam C Naj et al.   NATURE GENETICS

Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

(2011) Paul Hollingworth et al.   NATURE GENETICS

TOMM40 poly-T repeat lengths, age of onset and psychosis risk in Alzheimer disease

(2011) Su Hee Chu et al.   NEUROBIOLOGY OF AGING

Disease Risk Links to Gene Regulation

(2011) E. Pennisi   SCIENCE

Genome-Wide Association of Familial Late-Onset Alzheimer's Disease Replicates BIN1 and CLU and Nominates CUGBP2 in Interaction with APOE

(2011) Ellen M. Wijsman et al.   PLoS Genetics

CR1is associated with amyloid plaque burden and age-related cognitive decline

(2010) Lori B. Chibnik et al.   ANNALS OF NEUROLOGY

Meta-analysis Confirms CR1, CLU, and PICALM as Alzheimer Disease Risk Loci and Reveals Interactions With APOE Genotypes

(2010) Gyungah Jun   ARCHIVES OF NEUROLOGY

Identification of Novel Loci for Alzheimer Disease and Replication of CLU, PICALM, and BIN1 in Caribbean Hispanic Individuals

(2010) Joseph H. Lee et al.   ARCHIVES OF NEUROLOGY

Genetic evidence for the involvement of lipid metabolism in Alzheimer's disease

(2010) Lesley Jones et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Cholesterol-related genes in Alzheimer's disease

(2010) M. Axel Wollmer   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Alzheimer’s disease phenotypes and genotypes associated with mutations in presenilin 2

(2010) Suman Jayadev et al.   BRAIN

Evolution of CD33-related siglecs: regulating host immune functions and escaping pathogen exploitation?

(2010) Huan Cao et al.   IMMUNOLOGY

Genome-wide Analysis of Genetic Loci Associated With Alzheimer Disease

(2010) Sudha Seshadri   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

A Presenilin-1 Mutation Identified in Familial Alzheimer Disease with Cotton Wool Plaques Causes a Nearly Complete Loss of γ-Secretase Activity

(2010) Elizabeth A. Heilig et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activation of EphA receptors on CD4+ CD45RO+ memory cells stimulates migration

(2010) H. L. Holen et al.   JOURNAL OF LEUKOCYTE BIOLOGY

γ-secretases: from cell biology to therapeutic strategies

(2010) Bruno A Bergmans et al.   LANCET NEUROLOGY

From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus

(2010) Kiran Musunuru et al.   NATURE

Biological, clinical and population relevance of 95 loci for blood lipids

(2010) Tanya M. Teslovich et al.   NATURE

Whole genome association study of brain-wide imaging phenotypes for identifying quantitative trait loci in MCI and AD: A study of the ADNI cohort

(2010) Li Shen et al.   NEUROIMAGE

PCDH11X variation is not associated with late-onset Alzheimer disease susceptibility

(2010) Gary W. Beecham et al.   PSYCHIATRIC GENETICS

 -Secretase Gene Mutations in Familial Acne Inversa

(2010) B. Wang et al.   SCIENCE

The pursuit of susceptibility genes for Alzheimer's disease: progress and prospects

(2010) Kristel Sleegers et al.   TRENDS IN GENETICS

Dementia Revealed: Novel Chromosome 6 Locus for Late-Onset Alzheimer Disease Provides Genetic Evidence for Folate-Pathway Abnormalities

(2010) Adam C. Naj et al.   PLoS Genetics

Genome-wide Association Study Implicates a Chromosome 12 Risk Locus for Late-Onset Alzheimer Disease

(2009) Gary W. Beecham et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Basic and Clinical Immunology of Siglecs

(2009) Stephan von Gunten et al.   Annals of the New York Academy of Sciences

Association of SORL1 gene variants with Alzheimer's disease

(2009) Heike Kölsch et al.   BRAIN RESEARCH

Clusterin: A forgotten player in Alzheimer's disease

(2009) Tapio Nuutinen et al.   BRAIN RESEARCH REVIEWS

The Vps10p-domain receptor family

(2009) Guido Hermey   CELLULAR AND MOLECULAR LIFE SCIENCES

Synapse development and plasticity: roles of ephrin/Eph receptor signaling

(2009) Kwok-On Lai et al.   CURRENT OPINION IN NEUROBIOLOGY

Molecular genetic analysis of podocyte genes in focal segmental glomerulosclerosis—a review

(2009) M. M. Löwik et al.   EUROPEAN JOURNAL OF PEDIATRICS

EphA1 interacts with integrin-linked kinase and regulates cell morphology and motility

(2009) T. Yamazaki et al.   JOURNAL OF CELL SCIENCE

Identification of independent APP locus duplication in Japanese patients with early-onset Alzheimer disease

(2009) K Kasuga et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Clinical, Neuropathologic, and Biochemical Profile of the Amyloid Precursor Protein I716F Mutation

(2009) Cristina Guardia-Laguarta et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Hidradenitis suppurativa

(2009) J Revuz   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

Genetic variation in PCDH11X is associated with susceptibility to late-onset Alzheimer's disease

(2009) Minerva M Carrasquillo et al.   NATURE GENETICS

Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease

(2009) Jean-Charles Lambert et al.   NATURE GENETICS

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

(2009) Denise Harold et al.   NATURE GENETICS

Apolipoprotein E and its receptors in Alzheimer's disease: pathways, pathogenesis and therapy

(2009) Guojun Bu   NATURE REVIEWS NEUROSCIENCE

The Role of Apolipoprotein E in Alzheimer's Disease

(2009) Jungsu Kim et al.   NEURON

SORL1 is genetically associated with Alzheimer disease in a Japanese population

(2009) Ryo Kimura et al.   NEUROSCIENCE LETTERS

A TOMM40 variable-length polymorphism predicts the age of late-onset Alzheimer's disease

(2009) A D Roses et al.   PHARMACOGENOMICS JOURNAL

Genome-wide Association Analysis Reveals Putative Alzheimer's Disease Susceptibility Loci in Addition to APOE

(2008) Lars Bertram et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Clinical and Neuropathological Features of the Arctic APP Gene Mutation Causing Early-Onset Alzheimer Disease

(2008) Hans Basun et al.   ARCHIVES OF NEUROLOGY

A genome-wide association study for late-onset Alzheimer's disease using DNA pooling

(2008) Richard Abraham et al.   BMC Medical Genomics

Generation and characterization ofEphA1receptor tyrosine kinase reporter knockout mice

(2008) Shannon L. Duffy et al.   GENESIS

SORL1 is genetically associated with increased risk for late-onset Alzheimer disease in the Belgian population

(2008) Karolien Bettens et al.   HUMAN MUTATION

Apolipoprotein E: structure determines function, from atherosclerosis to Alzheimer's disease to AIDS

(2008) Robert W. Mahley et al.   JOURNAL OF LIPID RESEARCH

Role of ATP-binding cassette transporters in brain lipid transport and neurological disease

(2008) Woojin Scott Kim et al.   JOURNAL OF NEUROCHEMISTRY

Assessment of Alzheimer’s disease case–control associations using family-based methods

(2008) Brit-Maren M. Schjeide et al.   NEUROGENETICS

No association of SORL1 SNPs with Alzheimer's disease

(2008) Ryan L. Minster et al.   NEUROSCIENCE LETTERS

Presenilins: Members of the γ-Secretase Quartets, But Part-Time Soloists Too

(2008) Tomoko Wakabayashi et al.   PHYSIOLOGY

Membrane Traffic and Muscle: Lessons from Human Disease

(2008) James J. Dowling et al.   TRAFFIC

Candidate Single-Nucleotide Polymorphisms From a Genomewide Association Study of Alzheimer Disease

(2007) Hao Li et al.   ARCHIVES OF NEUROLOGY

SORL1 haplotypes modulate risk of Alzheimer's disease in Chinese

(2007) E.K. Tan et al.   NEUROBIOLOGY OF AGING

SORL1 variants and risk of late-onset Alzheimer’s disease

(2007) Yonghong Li et al.   NEUROBIOLOGY OF DISEASE