Activation of the unfolded protein response and granulovacuolar degeneration are not common features of human prion pathology

Endoplasmic Reticulum Stress Induces Tau Pathology and Forms a Vicious Cycle: Implication in Alzheimer's Disease Pathogenesis

(2018) Yuen-Shan Ho et al.   JOURNAL OF ALZHEIMERS DISEASE

LiCl Attenuates Thapsigargin-Induced Tau Hyperphosphorylation by Inhibiting GSK-3β In Vivo and In Vitro

(2017) Zheng-Qi Fu et al.   JOURNAL OF ALZHEIMERS DISEASE

Granulovacuolar degeneration: a neurodegenerative change that accompanies tau pathology

(2016) Christoph Köhler   ACTA NEUROPATHOLOGICA

The unfolded protein response in neurodegenerative diseases: a neuropathological perspective

(2015) Wiep Scheper et al.   ACTA NEUROPATHOLOGICA

PERK inhibition prevents tau-mediated neurodegeneration in a mouse model of frontotemporal dementia

(2015) Helois Radford et al.   ACTA NEUROPATHOLOGICA

Partial restoration of protein synthesis rates by the small molecule ISRIB prevents neurodegeneration without pancreatic toxicity

(2015) M Halliday et al.   Cell Death & Disease

The unfolded protein response mediates reversible tau phosphorylation induced by metabolic stress

(2014) J M van der Harg et al.   Cell Death & Disease

Immunohistochemical characterization of novel monoclonal antibodies against the N-terminus of amyloid β-peptide

(2013) Nicolaas A. Verwey et al.   AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS

Unfolded protein response activates glycogen synthase kinase-3 via selective lysosomal degradation

(2013) Diana A.T. Nijholt et al.   NEUROBIOLOGY OF AGING

Oral Treatment Targeting the Unfolded Protein Response Prevents Neurodegeneration and Clinical Disease in Prion-Infected Mice

(2013) J. A. Moreno et al.   Science Translational Medicine

The unfolded protein response is activated in disease-affected brain regions in progressive supranuclear palsy and Alzheimer’s disease

(2013) Lauren D Stutzbach et al.   Acta Neuropathologica Communications

Endoplasmic reticulum dysfunction in neurological disease

(2012) Benoit D Roussel et al.   LANCET NEUROLOGY

Sustained translational repression by eIF2α-P mediates prion neurodegeneration

(2012) Julie A. Moreno et al.   NATURE

Human Prion Diseases in The Netherlands (1998–2009): Clinical, Genetic and Molecular Aspects

(2012) Casper Jansen et al.   PLoS One

Stages of granulovacuolar degeneration: their relation to Alzheimer’s disease and chronic stress response

(2011) Dietmar Rudolf Thal et al.   ACTA NEUROPATHOLOGICA

Familial prion disease with alzheimer disease-like tau pathology and clinical phenotype

(2011) Suman Jayadev et al.   ANNALS OF NEUROLOGY

A Second Case of Gerstmann-Sträussler-Scheinker Disease Linked to the G131V Mutation in the Prion Protein Gene in a Dutch Patient

(2011) Casper Jansen et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

The unfolded protein response is associated with early tau pathology in the hippocampus of tauopathies

(2011) Diana AT Nijholt et al.   JOURNAL OF PATHOLOGY

Expression of Mutant or Cytosolic PrP in Transgenic Mice and Cells Is Not Associated with Endoplasmic Reticulum Stress or Proteasome Dysfunction

(2011) Elena Quaglio et al.   PLoS One

A novel seven-octapeptide repeat insertion in the prion protein gene (PRNP) in a Dutch pedigree with Gerstmann–Sträussler–Scheinker disease phenotype: comparison with similar cases from the literature

(2010) Casper Jansen et al.   ACTA NEUROPATHOLOGICA

Tau, prions and Aβ: the triad of neurodegeneration

(2010) Lilla Reiniger et al.   ACTA NEUROPATHOLOGICA

The first case of protease-sensitive prionopathy (PSPr) in The Netherlands: a patient with an unusual GSS-like clinical phenotype

(2010) C. Jansen et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

The first case of fatal familial insomnia (FFI) in the Netherlands: a patient from Egyptian descent with concurrent four repeat tau deposits

(2010) C. Jansen et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Transcriptional Analysis Implicates Endoplasmic Reticulum Stress in Bovine Spongiform Encephalopathy

(2010) Yue Tang et al.   PLoS One

Prion Protein Misfolding Affects Calcium Homeostasis and Sensitizes Cells to Endoplasmic Reticulum Stress

(2010) Mauricio Torres et al.   PLoS One

Incidence and spectrum of sporadic Creutzfeldt–Jakob disease variants with mixed phenotype and co-occurrence of PrPSc types: an updated classification

(2009) Piero Parchi et al.   ACTA NEUROPATHOLOGICA

Prion protein amyloidosis with divergent phenotype associated with two novel nonsense mutations in PRNP

(2009) Casper Jansen et al.   ACTA NEUROPATHOLOGICA

The Unfolded Protein Response Is Activated in Pretangle Neurons in Alzheimer's Disease Hippocampus

(2009) Jeroen J.M. Hoozemans et al.   AMERICAN JOURNAL OF PATHOLOGY

Inherited Creutzfeldt-Jakob disease in a Dutch patient with a novel five octapeptide repeat insertion and unusual cerebellar morphology

(2009) C Jansen et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Panencephalopathic Creutzfeldt-Jakob disease in the Netherlands and the UK: clinical and pathological characteristics of nine patients

(2009) C. Jansen et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Prions: Protein Aggregation and Infectious Diseases

(2009) Adriano Aguzzi et al.   PHYSIOLOGICAL REVIEWS

Mutant Prion Protein Expression Causes Motor and Memory Deficits and Abnormal Sleep Patterns in a Transgenic Mouse Model

(2008) Sara Dossena et al.   NEURON

Physiology of the Prion Protein

(2008) Rafael Linden et al.   PHYSIOLOGICAL REVIEWS