Crystal structure of Clostridium difficile toxin A

Masking autoprocessing of Clostridium difficile toxin A by the C-terminus combined repetitive oligo peptides

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Burden of Clostridium difficile Infection in the United States

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Mechanism of Action and Epitopes ofClostridium difficileToxin B-neutralizing Antibody Bezlotoxumab Revealed by X-ray Crystallography

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Translocation domain mutations affecting cellular toxicity identify the Clostridium difficile toxin B pore

(2014) Z. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Combined Repetitive Oligopeptides of Clostridium difficile Toxin A Counteract Premature Cleavage of the Glucosyl-Transferase Domain by Stabilizing Protein Conformation

(2014) Alexandra Olling et al.   Toxins

Structural Basis for Antibody Recognition in the Receptor-binding Domains of Toxins A and B fromClostridium difficile

(2013) Tomohiko Murase et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Determinants ofClostridium difficileToxin A Glucosyltransferase Activity

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NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Clostridium difficile Toxin B Causes Epithelial Cell Necrosis through an Autoprocessing-Independent Mechanism

(2012) Nicole M. Chumbler et al.   PLoS Pathogens

Structural determinants for membrane insertion, pore formation and translocation of Clostridium difficile toxin B

(2011) Selda Genisyuerek et al.   MOLECULAR MICROBIOLOGY

Defining an allosteric circuit in the cysteine protease domain of Clostridium difficile toxins

(2011) Aimee Shen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Rational Design of Inhibitors and Activity-Based Probes Targeting Clostridium difficile Virulence Factor TcdB

(2010) Aaron W. Puri et al.   CHEMISTRY & BIOLOGY

Four Distinct Structural Domains in Clostridium difficile Toxin B Visualized Using SAXS

(2010) David Albesa-Jové et al.   JOURNAL OF MOLECULAR BIOLOGY

Autoproteolytic cleavage mediates cytotoxicity of Clostridium difficile toxin A

(2010) Isa Kreimeyer et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Treatment with Monoclonal Antibodies againstClostridium difficileToxins

(2010) Israel Lowy et al.   NEW ENGLAND JOURNAL OF MEDICINE

Structural organization of the functional domains of Clostridium difficile toxins A and B

(2010) R. N. Pruitt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Membrane Topography of the Diphtheria Toxin T Domain Linked to the A Chain Reveals a Transient Transmembrane Hairpin and Potential Translocation Mechanisms

(2009) Jie Wang et al.   BIOCHEMISTRY

Structure-Function Analysis of Inositol Hexakisphosphate-induced Autoprocessing inClostridium difficileToxin A

(2009) Rory N. Pruitt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Clostridium difficile— More Difficult Than Ever

(2008) Ciarán P. Kelly et al.   NEW ENGLAND JOURNAL OF MEDICINE

Structure and mode of action of clostridial glucosylating toxins: the ABCD model

(2008) Thomas Jank et al.   TRENDS IN MICROBIOLOGY