Rescue of non-human primates from advanced Sudan ebolavirus infection with lipid encapsulated siRNA

Ebola Virus Persistence in Semen of Male Survivors

(2016) Timothy M. Uyeki et al.   CLINICAL INFECTIOUS DISEASES

Ebola Virus Disease Complications as Experienced by Survivors in Sierra Leone

(2016) Amanda Tiffany et al.   CLINICAL INFECTIOUS DISEASES

Late Ebola virus relapse causing meningoencephalitis: a case report

(2016) Michael Jacobs et al.   LANCET

Early clinical sequelae of Ebola virus disease in Sierra Leone: a cross-sectional study

(2016) John G Mattia et al.   LANCET INFECTIOUS DISEASES

Bispecific Antibody Affords Complete Post-Exposure Protection of Mice from Both Ebola (Zaire) and Sudan Viruses

(2016) Julia C. Frei et al.   Scientific Reports

Antibody Treatment of Ebola and Sudan Virus Infection via a Uniquely Exposed Epitope within the Glycoprotein Receptor-Binding Site

(2016) Katie A. Howell et al.   Cell Reports

Experimental Treatment of Ebola Virus Disease with TKM-130803: A Single-Arm Phase 2 Clinical Trial

(2016) Jake Dunning et al.   PLOS MEDICINE

Discovery of an antibody for pan-ebolavirus therapy

(2016) Wakako Furuyama et al.   Scientific Reports

Ebola viral load at diagnosis associates with patient outcome and outbreak evolution

(2015) Marc-Antoine de La Vega et al.   JOURNAL OF CLINICAL INVESTIGATION

The Contribution of Ebola Viral Load at Admission and Other Patient Characteristics to Mortality in a Médecins Sans Frontières Ebola Case Management Centre, Kailahun, Sierra Leone, June–October 2014

(2015) Gabriel Fitzpatrick et al.   JOURNAL OF INFECTIOUS DISEASES

Different Temporal Effects of Ebola Virus VP35 and VP24 Proteins on Global Gene Expression in Human Dendritic Cells

(2015) Philipp A. Ilinykh et al.   JOURNAL OF VIROLOGY

Macaque Monoclonal Antibodies Targeting Novel Conserved Epitopes within Filovirus Glycoprotein

(2015) Zhen-Yong Keck et al.   JOURNAL OF VIROLOGY

Pan-ebolavirus and Pan-filovirus Mouse Monoclonal Antibodies: Protection against Ebola and Sudan Viruses

(2015) Frederick W. Holtsberg et al.   JOURNAL OF VIROLOGY

Long-term sequelae after Ebola virus disease in Bundibugyo, Uganda: a retrospective cohort study

(2015) Danielle V Clark et al.   LANCET INFECTIOUS DISEASES

Lipid nanoparticle siRNA treatment of Ebola-virus-Makona-infected nonhuman primates

(2015) Emily P. Thi et al.   NATURE

Molecular Evidence of Sexual Transmission of Ebola Virus

(2015) Suzanne E. Mate et al.   NEW ENGLAND JOURNAL OF MEDICINE

Identification of a New Ribonucleoside Inhibitor of Ebola Virus Replication

(2015) Olivier Reynard et al.   Viruses-Basel

A Single Phosphorodiamidate Morpholino Oligomer Targeting VP24 Protects Rhesus Monkeys against Lethal Ebola Virus Infection

(2015) Travis K. Warren et al.   mBio

Current issues of RNAi therapeutics delivery and development

(2014) D. Haussecker   JOURNAL OF CONTROLLED RELEASE

Clinical Illness and Outcomes in Patients with Ebola in Sierra Leone

(2014) John S. Schieffelin et al.   NEW ENGLAND JOURNAL OF MEDICINE

Marburg virus infection in nonhuman primates: Therapeutic treatment by lipid-encapsulated siRNA

(2014) E. P. Thi et al.   Science Translational Medicine

Formulated Minimal-Length Synthetic Small Hairpin RNAs Are Potent Inhibitors of Hepatitis C Virus in Mice With Humanized Livers

(2013) Han Ma et al.   GASTROENTEROLOGY

Protection Against Lethal Marburg Virus Infection Mediated by Lipid Encapsulated Small Interfering RNA

(2013) Raul Ursic-Bedoya et al.   JOURNAL OF INFECTIOUS DISEASES

Venezuelan Equine Encephalitis Virus Replicon Particle Vaccine Protects Nonhuman Primates from Intramuscular and Aerosol Challenge with Ebolavirus

(2013) A. S. Herbert et al.   JOURNAL OF VIROLOGY

Therapeutic Intervention of Ebola Virus Infection in Rhesus Macaques with the MB-003 Monoclonal Antibody Cocktail

(2013) J. Pettitt et al.   Science Translational Medicine

Sustained protection against Ebola virus infection following treatment of infected nonhuman primates with ZMAb

(2013) Xiangguo Qiu et al.   Scientific Reports

The Ebolavirus VP24 Protein Blocks Phosphorylation of p38 Mitogen-Activated Protein Kinase

(2011) Peter Halfmann et al.   JOURNAL OF INFECTIOUS DISEASES

Ebolavirus Proteins Suppress the Effects of Small Interfering RNA by Direct Interaction with the Mammalian RNA Interference Pathway

(2011) G. Fabozzi et al.   JOURNAL OF VIROLOGY

Protection of Nonhuman Primates against Two Species of Ebola Virus Infection with a Single Complex Adenovirus Vector

(2010) W. D. Pratt et al.   Clinical and Vaccine Immunology

Mutations Abrogating VP35 Interaction with Double-Stranded RNA Render Ebola Virus Avirulent in Guinea Pigs

(2010) K. C. Prins et al.   JOURNAL OF VIROLOGY

Postexposure protection of non-human primates against a lethal Ebola virus challenge with RNA interference: a proof-of-concept study

(2010) Thomas W Geisbert et al.   LANCET

Rational design of cationic lipids for siRNA delivery

(2010) Sean C Semple et al.   NATURE BIOTECHNOLOGY

Structural basis for dsRNA recognition and interferon antagonism by Ebola VP35

(2010) Daisy W Leung et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Ebolavirus VP24 Binding to Karyopherins Is Required for Inhibition of Interferon Signaling

(2009) M. Mateo et al.   JOURNAL OF VIROLOGY

Single-Injection Vaccine Protects Nonhuman Primates against Infection with Marburg Virus and Three Species of Ebola Virus

(2009) T. W. Geisbert et al.   JOURNAL OF VIROLOGY

Overcoming the Innate Immune Response to Small Interfering RNA

(2008) Adam Judge et al.   HUMAN GENE THERAPY

Vesicular stomatitis virus-based vaccines protect nonhuman primates against aerosol challenge with Ebola and Marburg viruses

(2008) Thomas W. Geisbert et al.   VACCINE