Lipid nanoparticle siRNA treatment of Ebola-virus-Makona-infected nonhuman primates

Evaluation of the Potential Impact of Ebola Virus Genomic Drift on the Efficacy of Sequence-Based Candidate Therapeutics

(2015) Jeffrey R. Kugelman et al.   mBio

Potential and Emerging Treatment Options for Ebola Virus Disease

(2014) Bryan M. Bishop   ANNALS OF PHARMACOTHERAPY

Inhibition of Hepatitis C Virus in Chimeric Mice by Short Synthetic Hairpin RNAs: Sequence Analysis of Surviving Virus Shows Added Selective Pressure of Combination Therapy

(2014) A. Dallas et al.   JOURNAL OF VIROLOGY

Emergence of Zaire Ebola Virus Disease in Guinea

(2014) Sylvain Baize et al.   NEW ENGLAND JOURNAL OF MEDICINE

Clinical Illness and Outcomes in Patients with Ebola in Sierra Leone

(2014) John S. Schieffelin et al.   NEW ENGLAND JOURNAL OF MEDICINE

Genomic surveillance elucidates Ebola virus origin and transmission during the 2014 outbreak

(2014) S. K. Gire et al.   SCIENCE

Challenges, Progress, and Opportunities: Proceedings of the Filovirus Medical Countermeasures Workshop

(2014) Rona Hirschberg et al.   Viruses-Basel

Formulated Minimal-Length Synthetic Small Hairpin RNAs Are Potent Inhibitors of Hepatitis C Virus in Mice With Humanized Livers

(2013) Han Ma et al.   GASTROENTEROLOGY

Ebola Virus Genome Plasticity as a Marker of Its Passaging History: A Comparison of In Vitro Passaging to Non-Human Primate Infection

(2012) Jeffrey R. Kugelman et al.   PLoS One

Genomic RNA Editing and Its Impact on Ebola Virus Adaptation During Serial Passages in Cell Culture and Infection of Guinea Pigs

(2011) Valentina A. Volchkova et al.   JOURNAL OF INFECTIOUS DISEASES

Enforced viral replication activates adaptive immunity and is essential for the control of a cytopathic virus

(2011) Nadine Honke et al.   NATURE IMMUNOLOGY

Postexposure protection of non-human primates against a lethal Ebola virus challenge with RNA interference: a proof-of-concept study

(2010) Thomas W Geisbert et al.   LANCET

Profiling of mismatch discrimination in RNAi enabled rational design of allele-specific siRNAs

(2009) Huang Huang et al.   NUCLEIC ACIDS RESEARCH