Spatial Genome Organization and Its Emerging Role as a Potential Diagnosis Tool
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Title
Spatial Genome Organization and Its Emerging Role as a Potential Diagnosis Tool
Authors
Keywords
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Journal
Frontiers in Genetics
Volume 7, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2016-07-26
DOI
10.3389/fgene.2016.00134
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Note: Only part of the references are listed.- Three-Dimensional Quantitative Imaging of Telomeres in Buccal Cells Identifies Mild, Moderate, and Severe Alzheimer's Disease Patients
- (2018) Shubha Mathur et al. JOURNAL OF ALZHEIMERS DISEASE
- A role for chromatin topology in imprinted domain regulation
- (2016) William A. MacDonald et al. Biochemistry and Cell Biology
- Chromatin changes predict recurrence after radical prostatectomy
- (2016) Tarjei S Hveem et al. BRITISH JOURNAL OF CANCER
- Cancer statistics, 2016
- (2016) Rebecca L. Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Chromosomal aneuploidies induced upon Lamin B2 depletion are mislocalized in the interphase nucleus
- (2016) Devika Ranade et al. CHROMOSOMA
- How to rule the nucleus: divide et impera
- (2016) Irina Solovei et al. CURRENT OPINION IN CELL BIOLOGY
- Histones and histone modifications in perinuclear chromatin anchoring: from yeast to man
- (2016) Jennifer C Harr et al. EMBO REPORTS
- Tissue-of-origin-specific gene repositioning in breast and prostate cancer
- (2016) Karen J. Meaburn et al. HISTOCHEMISTRY AND CELL BIOLOGY
- Strategies to regulate transcription factor–mediated gene positioning and interchromosomal clustering at the nuclear periphery
- (2016) Carlo Randise-Hinchliff et al. JOURNAL OF CELL BIOLOGY
- Global reorganization of budding yeast chromosome conformation in different physiological conditions
- (2016) Elisa Dultz et al. JOURNAL OF CELL BIOLOGY
- Locus-specific gene repositioning in prostate cancer
- (2016) Marc Leshner et al. MOLECULAR BIOLOGY OF THE CELL
- Cause and Consequence of Tethering a SubTAD to Different Nuclear Compartments
- (2016) Patrick J. Wijchers et al. MOLECULAR CELL
- Topologically associated domains enriched for lineage-specific genes reveal expression-dependent nuclear topologies during myogenesis
- (2016) Daniel S. Neems et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Nongenetic functions of the genome
- (2016) M. Bustin et al. SCIENCE
- Activation of proto-oncogenes by disruption of chromosome neighborhoods
- (2016) D. Hnisz et al. SCIENCE
- Cajal bodies are linked to genome conformation
- (2016) Qiuyan Wang et al. Nature Communications
- A diffusion model for the coordination of DNA replication in Schizosaccharomyces pombe
- (2016) T. Pichugina et al. Scientific Reports
- The 2014 International Society of Urological Pathology (ISUP) Consensus Conference on Gleason Grading of Prostatic Carcinoma
- (2015) Jonathan I. Epstein et al. AMERICAN JOURNAL OF SURGICAL PATHOLOGY
- Trends in the lifetime risk of developing cancer in Great Britain: comparison of risk for those born from 1930 to 1960
- (2015) A S Ahmad et al. BRITISH JOURNAL OF CANCER
- Global cancer statistics, 2012
- (2015) Lindsey A. Torre et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Genome-wide Maps of Nuclear Lamina Interactions in Single Human Cells
- (2015) Jop Kind et al. CELL
- Identification of Gene Positioning Factors Using High-Throughput Imaging Mapping
- (2015) Sigal Shachar et al. CELL
- Disruptions of Topological Chromatin Domains Cause Pathogenic Rewiring of Gene-Enhancer Interactions
- (2015) Darío G. Lupiáñez et al. CELL
- Transient Pairing of Homologous Oct4 Alleles Accompanies the Onset of Embryonic Stem Cell Differentiation
- (2015) Megan S. Hogan et al. Cell Stem Cell
- Expression of the DYRK1A gene correlates with its 3D positioning in the interphase nucleus of Down syndrome cells
- (2015) Nerea Paz et al. CHROMOSOME RESEARCH
- Characterization and dynamics of pericentromere-associated domains in mice
- (2015) Patrick J. Wijchers et al. GENOME RESEARCH
- Directed targeting of chromatin to the nuclear lamina is mediated by chromatin state and A-type lamins
- (2015) Jennifer C. Harr et al. JOURNAL OF CELL BIOLOGY
- Nuclear architecture dictates HIV-1 integration site selection
- (2015) Bruna Marini et al. NATURE
- The 3D folding of metazoan genomes correlates with the association of similar repetitive elements
- (2015) Axel Cournac et al. NUCLEIC ACIDS RESEARCH
- CTCF establishes discrete functional chromatin domains at theHoxclusters during differentiation
- (2015) Varun Narendra et al. SCIENCE
- Chromatin organization at the nuclear pore favours HIV replication
- (2015) Mickaël Lelek et al. Nature Communications
- Lamin A/C deficiency is an independent risk factor for cervical cancer
- (2015) Callinice D. Capo-chichi et al. CELLULAR ONCOLOGY
- Global Reorganization of the Nuclear Landscape in Senescent Cells
- (2015) Tamir Chandra et al. Cell Reports
- Spatial Positioning of All 24 Chromosomes in the Lymphocytes of Six Subjects: Evidence of Reproducible Positioning and Spatial Repositioning following DNA Damage with Hydrogen Peroxide and Ultraviolet B
- (2015) Dimitrios Ioannou et al. PLoS One
- Differential Predictive Roles of A- and B-Type Nuclear Lamins in Prostate Cancer Progression
- (2015) Irena Saarinen et al. PLoS One
- Three-dimensional Nuclear Telomere Architecture Is Associated with Differential Time to Progression and Overall Survival in Glioblastoma Patients
- (2015) Macoura Gadji et al. NEOPLASIA
- A 3D Map of the Human Genome at Kilobase Resolution Reveals Principles of Chromatin Looping
- (2014) Suhas S.P. Rao et al. CELL
- Nuclear Deformability Constitutes a Rate-Limiting Step During Cell Migration in 3-D Environments
- (2014) Patricia M. Davidson et al. Cellular and Molecular Bioengineering
- HSP70 Transgene Directed Motion to Nuclear Speckles Facilitates Heat Shock Activation
- (2014) Nimish Khanna et al. CURRENT BIOLOGY
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- (2014) RUTH MIKELSAAR et al. JOURNAL OF GENETICS
- Obesity-associated variants within FTO form long-range functional connections with IRX3
- (2014) Scott Smemo et al. NATURE
- High-risk prostate cancer—classification and therapy
- (2014) Albert J. Chang et al. Nature Reviews Clinical Oncology
- Topological organization of multichromosomal regions by the long intergenic noncoding RNA Firre
- (2014) Ezgi Hacisuleyman et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Chromosome conformation maps in fission yeast reveal cell cycle dependent sub nuclear structure
- (2014) Ralph S. Grand et al. NUCLEIC ACIDS RESEARCH
- Chromatin decondensation is sufficient to alter nuclear organization in embryonic stem cells
- (2014) Pierre Therizols et al. SCIENCE
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- (2014) Theodorus H. Van der Kwast VIRCHOWS ARCHIV
- Twenty five year follow-up for breast cancer incidence and mortality of the Canadian National Breast Screening Study: randomised screening trial
- (2014) A. B. Miller et al. BMJ-British Medical Journal
- Differential Spatial Repositioning of Activated Genes in Biomphalaria glabrata Snails Infected with Schistosoma mansoni
- (2014) Halime D. Arican-Goktas et al. PLoS Neglected Tropical Diseases
- Single-Cell Dynamics of Genome-Nuclear Lamina Interactions
- (2013) Jop Kind et al. CELL
- Genome Architecture: Domain Organization of Interphase Chromosomes
- (2013) Wendy A. Bickmore et al. CELL
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- (2013) Irina Solovei et al. CELL
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- (2013) Justin Demmerle et al. CHROMOSOME RESEARCH
- β-Globin cis-elements determine differential nuclear targeting through epigenetic modifications
- (2013) Qian Bian et al. JOURNAL OF CELL BIOLOGY
- Combined Fluorescent-Chromogenic In Situ Hybridization for Identification and Laser Microdissection of Interphase Chromosomes
- (2013) Nerea Paz et al. PLoS One
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- (2013) Michael J. Zeitz et al. PLoS One
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- (2013) V. Roukos et al. SCIENCE
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- (2013) Ishita S Mehta et al. GENOME BIOLOGY
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- (2013) Nikolaj Zuleger et al. GENOME BIOLOGY
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- (2012) Helen A Foster et al. BMC CELL BIOLOGY
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- (2012) Lu Kong et al. CARCINOGENESIS
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- (2012) Joseph M. Zullo et al. CELL
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- (2012) Benjamin D. Towbin et al. CELL
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- (2012) Tom Sexton et al. CELL
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- (2012) E. Josephine Clowney et al. CELL
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- (2012) Nard Kubben et al. CHROMOSOMA
- Spatial congregation of STAT binding directs selective nuclear architecture during T-cell functional differentiation
- (2012) O. Hakim et al. GENOME RESEARCH
- Correlated alterations in genome organization, histone methylation, and DNA-lamin A/C interactions in Hutchinson-Gilford progeria syndrome
- (2012) R. P. McCord et al. GENOME RESEARCH
- Physical tethering and volume exclusion determine higher-order genome organization in budding yeast
- (2012) H. Tjong et al. GENOME RESEARCH
- DNA damage defines sites of recurrent chromosomal translocations in B lymphocytes
- (2012) Ofir Hakim et al. NATURE
- Topological domains in mammalian genomes identified by analysis of chromatin interactions
- (2012) Jesse R. Dixon et al. NATURE
- Spatial partitioning of the regulatory landscape of the X-inactivation centre
- (2012) Elphège P. Nora et al. NATURE
- Effect of Three Decades of Screening Mammography on Breast-Cancer Incidence
- (2012) Archie Bleyer et al. NEW ENGLAND JOURNAL OF MEDICINE
- Is the Ki-67 labelling index ready for clinical use?
- (2011) W. Jonat et al. ANNALS OF ONCOLOGY
- Translocation-Capture Sequencing Reveals the Extent and Nature of Chromosomal Rearrangements in B Lymphocytes
- (2011) Isaac A. Klein et al. CELL
- Genome-wide Translocation Sequencing Reveals Mechanisms of Chromosome Breaks and Rearrangements in B Cells
- (2011) Roberto Chiarle et al. CELL
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- (2011) Douglas Hanahan et al. CELL
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- (2011) Shelagh Boyle et al. CHROMOSOME RESEARCH
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- (2011) C Dupont et al. CLINICAL GENETICS
- An EDMD Mutation in C. elegans Lamin Blocks Muscle-Specific Gene Relocation and Compromises Muscle Integrity
- (2011) Anna Mattout et al. CURRENT BIOLOGY
- Gene positioning and expression
- (2011) Defne Egecioglu et al. CURRENT OPINION IN CELL BIOLOGY
- Loss of lamin A/C expression in stage II and III colon cancer is associated with disease recurrence
- (2011) E.J.Th. Belt et al. EUROPEAN JOURNAL OF CANCER
- Diverse gene reprogramming events occur in the same spatial clusters of distal regulatory elements
- (2011) O. Hakim et al. GENOME RESEARCH
- Farnesyltransferase inhibitor treatment restores chromosome territory positions and active chromosome dynamics in Hutchinson-Gilford progeria syndrome cells
- (2011) Ishita S Mehta et al. GENOME BIOLOGY
- The lamin protein family
- (2011) Travis A Dittmer et al. GENOME BIOLOGY
- Functional interactions between nucleoporins and chromatin
- (2010) Yun Liang et al. CURRENT OPINION IN CELL BIOLOGY
- The effect of translocation-induced nuclear reorganization on gene expression
- (2010) L. Harewood et al. GENOME RESEARCH
- Non-random organization of the Biomphalaria glabrata genome in interphase Bge cells and the spatial repositioning of activated genes in cells co-cultured with Schistosoma mansoni
- (2010) Matty Knight et al. INTERNATIONAL JOURNAL FOR PARASITOLOGY
- Time Trends and Local Variation in Primary Treatment of Localized Prostate Cancer
- (2010) Matthew R. Cooperberg et al. JOURNAL OF CLINICAL ONCOLOGY
- Overdiagnosis in Cancer
- (2010) H. G. Welch et al. JNCI-Journal of the National Cancer Institute
- Classification and prognosis of invasive breast cancer: from morphology to molecular taxonomy
- (2010) Stuart J Schnitt MODERN PATHOLOGY
- High-Resolution Whole-Genome Sequencing Reveals That Specific Chromatin Domains from Most Human Chromosomes Associate with Nucleoli
- (2010) Silvana van Koningsbruggen et al. MOLECULAR BIOLOGY OF THE CELL
- Molecular Maps of the Reorganization of Genome-Nuclear Lamina Interactions during Differentiation
- (2010) Daan Peric-Hupkes et al. MOLECULAR CELL
- Genomics tools for unraveling chromosome architecture
- (2010) Bas van Steensel et al. NATURE BIOTECHNOLOGY
- DNA zip codes control an ancient mechanism for gene targeting to the nuclear periphery
- (2010) Sara Ahmed et al. NATURE CELL BIOLOGY
- Molecular circuits of solid tumors: prognostic and predictive tools for bedside use
- (2010) Charles Ferté et al. Nature Reviews Clinical Oncology
- Altered Intra-Nuclear Organisation of Heterochromatin and Genes in ICF Syndrome
- (2010) Andrew Jefferson et al. PLoS One
- Altered Chromosomal Positioning, Compaction, and Gene Expression with a Lamin A/C Gene Mutation
- (2010) Stephanie K. Mewborn et al. PLoS One
- Gene Positioning
- (2010) C. Ferrai et al. Cold Spring Harbor Perspectives in Biology
- Initial Genomics of the Human Nucleolus
- (2010) Attila Németh et al. PLoS Genetics
- Rapid chromosome territory relocation by nuclear motor activity in response to serum removal in primary human fibroblasts
- (2010) Ishita S Mehta et al. GENOME BIOLOGY
- Nuclear Architecture of Rod Photoreceptor Cells Adapts to Vision in Mammalian Evolution
- (2009) Irina Solovei et al. CELL
- Nuclear Receptor-Induced Chromosomal Proximity and DNA Breaks Underlie Specific Translocations in Cancer
- (2009) Chunru Lin et al. CELL
- Spatial allelic imbalance of BCL2 genes and chromosome 18 territories in nonneoplastic and neoplastic cervical squamous epithelium
- (2009) Thorsten Wiech et al. EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
- Global identification of yeast chromosome interactions using Genome conformation capture
- (2009) C.D.M. Rodley et al. FUNGAL GENETICS AND BIOLOGY
- Gene loops function to maintain transcriptional memory through interaction with the nuclear pore complex
- (2009) Sue Mei Tan-Wong et al. GENES & DEVELOPMENT
- Lack of bystander activation shows that localization exterior to chromosome territories is not sufficient to up-regulate gene expression
- (2009) C. Morey et al. GENOME RESEARCH
- Disease-specific gene repositioning in breast cancer
- (2009) Karen J. Meaburn et al. JOURNAL OF CELL BIOLOGY
- Risk Assessment for Prostate Cancer Metastasis and Mortality at the Time of Diagnosis
- (2009) Matthew R. Cooperberg et al. JNCI-Journal of the National Cancer Institute
- Lead Time and Overdiagnosis in Prostate-Specific Antigen Screening: Importance of Methods and Context
- (2009) G. Draisma et al. JNCI-Journal of the National Cancer Institute
- Dynamic changes of territories 17 and 18 during EBV-infection of human lymphocytes
- (2009) Chunxiang Li et al. MOLECULAR BIOLOGY REPORTS
- Preferential associations between co-regulated genes reveal a transcriptional interactome in erythroid cells
- (2009) Stefan Schoenfelder et al. NATURE GENETICS
- Gene deregulation and spatial genome reorganization near breakpoints prior to formation of translocations in anaplastic large cell lymphoma
- (2009) S. Mathas et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A progeria mutation reveals functions for lamin A in nuclear assembly, architecture, and chromosome organization
- (2009) P. Taimen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Induced Chromosomal Proximity and Gene Fusions in Prostate Cancer
- (2009) R.-S. Mani et al. SCIENCE
- Comprehensive Mapping of Long-Range Interactions Reveals Folding Principles of the Human Genome
- (2009) E. Lieberman-Aiden et al. SCIENCE
- The Meaning of Gene Positioning
- (2008) Takumi Takizawa et al. CELL
- Positioning of human chromosomes in murine cell hybrids according to synteny
- (2008) Karen J. Meaburn et al. CHROMOSOMA
- Allele-specific nuclear positioning of the monoallelically expressed astrocyte marker GFAP
- (2008) T. Takizawa et al. GENES & DEVELOPMENT
- Locus-specific and activity-independent gene repositioning during early tumorigenesis
- (2008) Karen J. Meaburn et al. JOURNAL OF CELL BIOLOGY
- A genetic locus targeted to the nuclear periphery in living cells maintains its transcriptional competence
- (2008) R. Ileng Kumaran et al. JOURNAL OF CELL BIOLOGY
- Domain organization of human chromosomes revealed by mapping of nuclear lamina interactions
- (2008) Lars Guelen et al. NATURE
- Transcriptional repression mediated by repositioning of genes to the nuclear lamina
- (2008) K. L. Reddy et al. NATURE
- High-resolution statistical mapping reveals gene territories in live yeast
- (2008) Axel B Berger et al. NATURE METHODS
- Maintenance of Long-Range DNA Interactions after Inhibition of Ongoing RNA Polymerase II Transcription
- (2008) Robert-Jan Palstra et al. PLoS One
- Lamin A/C Is a Risk Biomarker in Colorectal Cancer
- (2008) Naomi D. Willis et al. PLoS One
- Global Reorganization of Replication Domains During Embryonic Stem Cell Differentiation
- (2008) Ichiro Hiratani et al. PLOS BIOLOGY
- Recruitment to the Nuclear Periphery Can Alter Expression of Genes in Human Cells
- (2008) Lee E. Finlan et al. PLoS Genetics
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