Developmental Changes in Pain and Spinal Immune Gene Expression after Radicular Trauma in the Rat

Nerve injury and neuropathic pain — A question of age

(2016) Maria Fitzgerald et al.   EXPERIMENTAL NEUROLOGY

Direct and indirect pharmacological modulation of CCL2/CCR2 pathway results in attenuation of neuropathic pain — In vivo and in vitro evidence

(2016) Anna Piotrowska et al.   JOURNAL OF NEUROIMMUNOLOGY

Beneficial properties of maraviroc on neuropathic pain development and opioid effectiveness in rats

(2016) Klaudia Kwiatkowski et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Burst and Tonic Spinal Cord Stimulation Differentially Activate GABAergic Mechanisms to Attenuate Pain in a Rat Model of Cervical Radiculopathy

(2015) Nathan D. Crosby et al.   IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING

Evidence for a distinct neuro-immune signature in rats that develop behavioural disability after nerve injury

(2015) Paul J Austin et al.   Journal of Neuroinflammation

Neuropathic Pain Is Constitutively Suppressed in Early Life by Anti-Inflammatory Neuroimmune Regulation

(2015) R. McKelvey et al.   JOURNAL OF NEUROSCIENCE

Different immune cells mediate mechanical pain hypersensitivity in male and female mice

(2015) Robert E Sorge et al.   NATURE NEUROSCIENCE

Gene Therapy for Neuropathic Pain by Silencing of TNF-α Expression with Lentiviral Vectors Targeting the Dorsal Root Ganglion in Mice

(2014) Nobuhiro Ogawa et al.   PLoS One

Neuropathic pain in children

(2013) R. F. Howard et al.   ARCHIVES OF DISEASE IN CHILDHOOD

Higher pain perception and lack of recovery from neuropathic pain in females: A behavioural, immunohistochemical, and proteomic investigation on sex-related differences in mice

(2013) Valentina Vacca et al.   PAIN

Dissociated modulation of conditioned place-preference and mechanical hypersensitivity by a TRPA1 channel antagonist in peripheral neuropathy

(2013) Hong Wei et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Anti-interleukin-6 receptor antibody reduces neuropathic pain following spinal cord injury in mice

(2013) TOMOTOSHI MURAKAMI et al.   Experimental and Therapeutic Medicine

Irritable Bowel Syndrome: Methods, Mechanisms, and Pathophysiology. Neural and neuro-immune mechanisms of visceral hypersensitivity in irritable bowel syndrome

(2012) Bin Feng et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Heterogeneity of macrophages in injured trigeminal nerves: Cytokine/chemokine expressing vs. phagocytic macrophages

(2012) SeungHwan Lee et al.   BRAIN BEHAVIOR AND IMMUNITY

Evidence That Spinal Astrocytes but Not Microglia Contribute to the Pathogenesis of Paclitaxel-Induced Painful Neuropathy

(2012) Haijun Zhang et al.   JOURNAL OF PAIN

Peritoneal Administration of Met-RANTES Attenuates Inflammatory and Nociceptive Responses in a Murine Neuropathic Pain Model

(2012) Jiin-Tarng Liou et al.   JOURNAL OF PAIN

The Emergence of Adolescent Onset Pain Hypersensitivity following Neonatal Nerve Injury

(2012) David Vega-Avelaira et al.   Molecular Pain

Transient nerve root compression load and duration differentially mediate behavioral sensitivity and associated spinal astrocyte activation and mGLuR5 expression

(2012) K.J. Nicholson et al.   NEUROSCIENCE

Pain’s peptide signature

(2012) Michael Costigan   PAIN

Absence of C–C motif chemokine ligand 5 in mice leads to decreased local macrophage recruitment and behavioral hypersensitivity in a murine neuropathic pain model

(2012) Jiin-Tarng Liou et al.   PAIN

Emerging role of Toll-like receptors in the control of pain and itch

(2012) Tong Liu et al.   Neuroscience Bulletin

Spinal Macrophage Migration Inhibitory Factor Is a Major Contributor to Rodent Neuropathic Pain-like Hypersensitivity

(2011) FuZhou Wang et al.   ANESTHESIOLOGY

Therapeutic targeting of innate immunity with Toll-like receptor 4 (TLR4) antagonists

(2011) Francesco Peri et al.   BIOTECHNOLOGY ADVANCES

The Dynamic TRPA1 Channel: A Suitable Pharmacological Pain Target?

(2011) Sheldon R. Garrison et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Immune responses of microglia in the spinal cord: Contribution to pain states

(2011) Dominic Schomberg et al.   EXPERIMENTAL NEUROLOGY

The effect of intrathecal administration of glial activation inhibitors on dorsal horn BDNF overexpression and hind paw mechanical allodynia in spinal nerve ligated rats

(2011) Xin Zhang et al.   JOURNAL OF NEURAL TRANSMISSION

The Role of the Medial Prefrontal Cortex in Innate Fear Regulation in Infants, Juveniles, and Adolescents

(2011) T. Chan et al.   JOURNAL OF NEUROSCIENCE

Spinal Cord Toll-Like Receptor 4 Mediates Inflammatory and Neuropathic Hypersensitivity in Male But Not Female Mice

(2011) R. E. Sorge et al.   JOURNAL OF NEUROSCIENCE

Schwann Cell Proliferation and Macrophage Infiltration Are Evident at Day 14 after Painful Cervical Nerve Root Compression in the Rat

(2011) Yu-Wen Chang et al.   JOURNAL OF NEUROTRAUMA

Brain-derived neurotrophic factor–activated astrocytes produce mechanical allodynia in neuropathic pain

(2011) X. Zhang et al.   NEUROSCIENCE

The neuro-immune balance in neuropathic pain: Involvement of inflammatory immune cells, immune-like glial cells and cytokines

(2010) Paul J. Austin et al.   JOURNAL OF NEUROIMMUNOLOGY

TNF-α and neuropathic pain - a review

(2010) Lawrence Leung et al.   Journal of Neuroinflammation

Neuropathic Pain in Children: Special Considerations

(2010) Gary A. Walco et al.   MAYO CLINIC PROCEEDINGS

Targeting astrocyte signaling for chronic pain

(2010) Yong-Jing Gao et al.   Neurotherapeutics

Chemokines, neuronal–glial interactions, and central processing of neuropathic pain

(2010) Yong-Jing Gao et al.   PHARMACOLOGY & THERAPEUTICS

Neuropathic Pain: A Maladaptive Response of the Nervous System to Damage

(2009) Michael Costigan et al.   Annual Review of Neuroscience

T-Cell Infiltration and Signaling in the Adult Dorsal Spinal Cord Is a Major Contributor to Neuropathic Pain-Like Hypersensitivity

(2009) M. Costigan et al.   JOURNAL OF NEUROSCIENCE

Differential Regulation of Immune Responses and Macrophage/Neuron Interactions in the Dorsal Root Ganglion in Young and Adult Rats following Nerve Injury

(2009) David Vega-Avelaira et al.   Molecular Pain

Transitions in infant learning are modulated by dopamine in the amygdala

(2009) Gordon A Barr et al.   NATURE NEUROSCIENCE

Brief, low frequency stimulation of rat peripheral C-fibres evokes prolonged microglial-induced central sensitization in adults but not in neonates

(2009) Gareth J. Hathway et al.   PAIN

The Reactions of Glial Cells and Endoneurial Macrophages in the Dorsal Root Ganglion and Their Contribution to Pain-Related Behavior After Application of Nucleus Pulposus Onto the Nerve Root in Rats

(2009) Ken-ichi Otoshi et al.   SPINE

CNS-infiltrating CD4+ T lymphocytes contribute to murine spinal nerve transection-induced neuropathic pain

(2008) Ling Cao et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Tumor necrosis factor receptor 1 induces interleukin-6 upregulation through NF-kappaB in a rat neuropathic pain model

(2008) Kyung-Min Lee et al.   EUROPEAN JOURNAL OF PAIN

Glia in pathological pain: A role for fractalkine

(2008) E.D. Milligan et al.   JOURNAL OF NEUROIMMUNOLOGY

Differential Implication of Proinflammatory Cytokine Interleukin-6 in the Development of Cephalic versus Extracephalic Neuropathic Pain in Rats

(2008) A. Latremoliere et al.   JOURNAL OF NEUROSCIENCE

Cytokine mRNA Expression in Painful Radiculopathy

(2008) Sarah M. Rothman et al.   JOURNAL OF PAIN

Pathological and protective roles of glia in chronic pain

(2008) Erin D. Milligan et al.   NATURE REVIEWS NEUROSCIENCE

Developmental characteristics of neuropathic pain induced by peripheral nerve injury of rats during neonatal period

(2008) Seung Keun Back et al.   NEUROSCIENCE RESEARCH