Evidence for a distinct neuro-immune signature in rats that develop behavioural disability after nerve injury

Depletion of Foxp3+ regulatory T cells increases severity of mechanical allodynia and significantly alters systemic cytokine levels following peripheral nerve injury

(2015) Justin G. Lees et al.   CYTOKINE

Anti-inflammatory T-cell shift in neuropathic pain

(2015) Benjamin Luchting et al.   Journal of Neuroinflammation

Injury-Dependent and Disability-Specific Lumbar Spinal Gene Regulation following Sciatic Nerve Injury in the Rat

(2015) Paul J. Austin et al.   PLoS One

Upregulation of tumor necrosis factor-alpha in nucleus accumbens attenuates morphine-induced rewarding in a neuropathic pain model

(2014) Ying Wu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Minocycline modulates neuropathic pain behaviour and cortical M1–M2 microglial gene expression in a rat model of depression

(2014) Nikita N. Burke et al.   BRAIN BEHAVIOR AND IMMUNITY

Rats with altered behaviour following nerve injury show evidence of centrally altered thyroid regulation

(2014) E. Kilburn-Watt et al.   BRAIN RESEARCH BULLETIN

Association between baseline IL-6 and 1-year recovery in lumbar radicular pain

(2014) E.I. Schistad et al.   EUROPEAN JOURNAL OF PAIN

Different patterns of morphological changes in the hippocampus and dentate gyrus accompany the differential expression of disability following nerve injury

(2014) Eszter Kalman et al.   JOURNAL OF ANATOMY

Individual differences in the peripheral immune system promote resilience versus susceptibility to social stress

(2014) Georgia E. Hodes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Clinical recovery from surgery correlates with single-cell immune signatures

(2014) B. Gaudilliere et al.   Science Translational Medicine

Differential Regulation of Glucocorticoid Receptor Expression in Distinct Columns of Periaqueductal Grey in Rats with Behavioural Disability Following Nerve Injury

(2013) David Mor et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Maternal Deprivation Is Associated With Sex-Dependent Alterations in Nociceptive Behavior and Neuroinflammatory Mediators in the Rat Following Peripheral Nerve Injury

(2013) Nikita N. Burke et al.   JOURNAL OF PAIN

Involvement of spinal microglia and interleukin-18 in the anti-nociceptive effect of dexmedetomidine in rats subjected to CCI

(2013) Shuang-Shuang Li et al.   NEUROSCIENCE LETTERS

Inflammatory T Helper 17 Cells Promote Depression-like Behavior in Mice

(2012) Eléonore Beurel et al.   BIOLOGICAL PSYCHIATRY

Systemic Administration of an Alpha-7 Nicotinic Acetylcholine Agonist Reverses Neuropathic Pain in Male Sprague Dawley Rats

(2012) Lisa C. Loram et al.   JOURNAL OF PAIN

A novel model of combined neuropathic and inflammatory pain displaying long-lasting allodynia and spontaneous pain-like behaviour

(2012) Andrew J. Allchorne et al.   NEUROSCIENCE RESEARCH

Regulatory T cells attenuate neuropathic pain following peripheral nerve injury and experimental autoimmune neuritis

(2012) Paul J. Austin et al.   PAIN

Increased Responsiveness of Peripheral Blood Mononuclear Cells to In Vitro TLR 2, 4 and 7 Ligand Stimulation in Chronic Pain Patients

(2012) Yuen H. Kwok et al.   PLoS One

CD4+CD25+ Regulatory T Cell Depletion Modulates Anxiety and Depression-Like Behaviors in Mice

(2012) Soo-Jeong Kim et al.   PLoS One

Evidence for cellular injury in the midbrain of rats following chronic constriction injury of the sciatic nerve

(2011) David Mor et al.   JOURNAL OF CHEMICAL NEUROANATOMY

T-bet deficient mice exhibit resistance to stress-induced development of depression-like behaviors

(2011) Soo-Jeong Kim et al.   JOURNAL OF NEUROIMMUNOLOGY

Wallerian degeneration: the innate-immune response to traumatic nerve injury

(2011) Shlomo Rotshenker   Journal of Neuroinflammation

Peripheral Nerve Injury Leads to Working Memory Deficits and Dysfunction of the Hippocampus by Upregulation of TNF-α in Rodents

(2011) Wen-Jie Ren et al.   NEUROPSYCHOPHARMACOLOGY

Chronic neuropathic pain-like behavior correlates with IL-1β expression and disrupts cytokine interactions in the hippocampus

(2011) Adriana del Rey et al.   PAIN

Chronic dizocilpine or apomorphine and development of neuropathy in two animal models II: Effects on brain cytokines and neurotrophins

(2010) Hassen Al-Amin et al.   EXPERIMENTAL NEUROLOGY

The neuro-immune balance in neuropathic pain: Involvement of inflammatory immune cells, immune-like glial cells and cytokines

(2010) Paul J. Austin et al.   JOURNAL OF NEUROIMMUNOLOGY

Tickets to the brain: Role of CCR2 and CX3CR1 in myeloid cell entry in the CNS

(2010) Marco Prinz et al.   JOURNAL OF NEUROIMMUNOLOGY

Interleukin-17 Contributes to Neuroinflammation and Neuropathic Pain Following Peripheral Nerve Injury in Mice

(2010) Cristina Fabiola Kim et al.   JOURNAL OF PAIN

Peripheral nerve injury differentially regulates dopaminergic pathways in the nucleus accumbens of rats with either ‘pain alone’ or ‘pain and disability’

(2010) P.J. Austin et al.   NEUROSCIENCE

Anatomically specific patterns of glial activation in the periaqueductal gray of the sub-population of rats showing pain and disability following chronic constriction injury of the sciatic nerve

(2010) D. Mor et al.   NEUROSCIENCE

Neuropathic Pain: A Maladaptive Response of the Nervous System to Damage

(2009) Michael Costigan et al.   Annual Review of Neuroscience

Dynamic regulation of spinal pro-inflammatory cytokine release in the rat in vivo following peripheral nerve injury

(2009) K.J. Whitehead et al.   BRAIN BEHAVIOR AND IMMUNITY

Effect of Memantine on the Levels of Neuropeptides and Microglial Cells in the Brain Regions of Rats with Neuropathic Pain

(2009) Katsumichi Takeda et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

T-Cell Infiltration and Signaling in the Adult Dorsal Spinal Cord Is a Major Contributor to Neuropathic Pain-Like Hypersensitivity

(2009) M. Costigan et al.   JOURNAL OF NEUROSCIENCE

Stress and IL-1β contribute to the development of depressive-like behavior following peripheral nerve injury

(2009) G J Norman et al.   MOLECULAR PSYCHIATRY

A neurocognitive model of attention to pain: Behavioral and neuroimaging evidence

(2009) Valéry Legrain et al.   PAIN

Coping style and immunity in animals: Making sense of individual variation

(2008) J.M. Koolhaas   BRAIN BEHAVIOR AND IMMUNITY

CNS-infiltrating CD4+ T lymphocytes contribute to murine spinal nerve transection-induced neuropathic pain

(2008) Ling Cao et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Interleukin-18-Mediated Microglia/Astrocyte Interaction in the Spinal Cord Enhances Neuropathic Pain Processing after Nerve Injury

(2008) K. Miyoshi et al.   JOURNAL OF NEUROSCIENCE

Supraspinal Glial-Neuronal Interactions Contribute to Descending Pain Facilitation

(2008) F. Wei et al.   JOURNAL OF NEUROSCIENCE

Evidence for a cytokine model of cognitive function

(2008) J. McAfoose et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

From inflammation to sickness and depression: when the immune system subjugates the brain

(2007) Robert Dantzer et al.   NATURE REVIEWS NEUROSCIENCE