Hide and Seek: How Lyme Disease Spirochetes Overcome Complement Attack

Identification of a novel pathogenic Borrelia species causing Lyme borreliosis with unusually high spirochaetaemia: a descriptive study

(2016) Bobbi S Pritt et al.   LANCET INFECTIOUS DISEASES

Sensitivity of Lyme Borreliosis Spirochetes to Serum Complement of Regular Zoo Animals: Potential Reservoir Competence of Some Exotic Vertebrates

(2016) Lucie Ticha et al.   VECTOR-BORNE AND ZOONOTIC DISEASES

Borrelia burgdorferi BBK32 Inhibits the Classical Pathway by Blocking Activation of the C1 Complement Complex

(2016) Brandon L. Garcia et al.   PLoS Pathogens

BGA66 and BGA71 facilitate complement resistance ofBorrelia bavariensisby inhibiting assembly of the membrane attack complex

(2015) Claudia Hammerschmidt et al.   MOLECULAR MICROBIOLOGY

Complement System Part I – Molecular Mechanisms of Activation and Regulation

(2015) Nicolas S. Merle et al.   Frontiers in Immunology

Versatile Roles of CspA Orthologs in Complement Inactivation of Serum-Resistant Lyme Disease Spirochetes

(2013) Claudia Hammerschmidt et al.   INFECTION AND IMMUNITY

BBA70 ofBorrelia burgdorferiIs a Novel Plasminogen-binding Protein

(2013) Arno Koenigs et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Borrelia valaisiana Resist Complement-Mediated Killing Independently of the Recruitment of Immune Regulators and Inactivation of Complement Components

(2013) Jasmin Schwab et al.   PLoS One

Complement evasion by Borrelia burgdorferi: it takes three to tango

(2013) Steven W. de Taeye et al.   TRENDS IN PARASITOLOGY

CspA from Borrelia burgdorferi Inhibits the Terminal Complement Pathway

(2013) T. Hallstrom et al.   mBio

Contribution of the Infection-Associated Complement Regulator-Acquiring Surface Protein 4 (ErpC) to Complement Resistance ofBorrelia burgdorferi

(2012) Claudia Hammerschmidt et al.   Clinical & Developmental Immunology

OspC Is Potent Plasminogen Receptor on Surface ofBorrelia burgdorferi

(2012) Özlem Önder et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Of ticks, mice and men: understanding the dual-host lifestyle of Lyme disease spirochaetes

(2012) Justin D. Radolf et al.   NATURE REVIEWS MICROBIOLOGY

Analysis of an Ordered, Comprehensive STM Mutant Library in Infectious Borrelia burgdorferi: Insights into the Genes Required for Mouse Infectivity

(2012) Tao Lin et al.   PLoS One

Exploring gaps in our knowledge on Lyme borreliosis spirochaetes – Updates on complex heterogeneity, ecology, and pathogenicity

(2012) Jan Franke et al.   Ticks and Tick-Borne Diseases

Complement regulator-acquiring surface proteins of Borrelia burgdorferi: Structure, function and regulation of gene expression

(2012) Peter Kraiczy et al.   Ticks and Tick-Borne Diseases

A Tick Mannose-Binding Lectin Inhibitor Interferes with the Vertebrate Complement Cascade to Enhance Transmission of the Lyme Disease Agent

(2011) Tim J. Schuijt et al.   Cell Host & Microbe

The expanding Lyme Borrelia complex—clinical significance of genomic species?

(2011) G. Stanek et al.   CLINICAL MICROBIOLOGY AND INFECTION

Role of complement in innate immunity and host defense

(2011) Leendert A. Trouw et al.   IMMUNOLOGY LETTERS

Whole-Genome Sequences of Borrelia bissettii, Borrelia valaisiana, and Borrelia spielmanii

(2011) S. E. Schutzer et al.   JOURNAL OF BACTERIOLOGY

Inadequate Binding of Immune Regulator Factor H Is Associated with Sensitivity of Borrelia lusitaniae to Human Complement

(2010) R. Dieterich et al.   INFECTION AND IMMUNITY

Complement Regulator–Acquiring Surface Protein 1 ofBorrelia burgdorferiBinds to Human Bone Morphogenic Protein 2, Several Extracellular Matrix Proteins, and Plasminogen

(2010) Teresia Hallström et al.   JOURNAL OF INFECTIOUS DISEASES

Complement: a key system for immune surveillance and homeostasis

(2010) Daniel Ricklin et al.   NATURE IMMUNOLOGY

Complement Factor H-Related Proteins CFHR2 and CFHR5 Represent Novel Ligands for the Infection-Associated CRASP Proteins of Borrelia burgdorferi

(2010) Corinna Siegel et al.   PLoS One

Complement and immune defense: From innate immunity to human diseases

(2009) Peter F. Zipfel   IMMUNOLOGY LETTERS

Comparative Analysis of the Properties and Ligand Binding Characteristics of CspZ, a Factor H Binding Protein, Derived from Borrelia burgdorferi Isolates of Human Origin

(2009) E. A. Rogers et al.   INFECTION AND IMMUNITY

CspA-Mediated Binding of Human Factor H Inhibits Complement Deposition and Confers Serum Resistance in Borrelia burgdorferi

(2009) M. R. Kenedy et al.   INFECTION AND IMMUNITY

Functional Characterization of Borrelia spielmanii Outer Surface Proteins That Interact with Distinct Members of the Human Factor H Protein Family and with Plasminogen

(2009) A. Seling et al.   INFECTION AND IMMUNITY

Relapsing fever - a forgotten disease revealed

(2009) S.J. Cutler   JOURNAL OF APPLIED MICROBIOLOGY

Binding of the complement inhibitor C4b-binding protein to Lyme disease borreliae

(2009) Johanna Pietikäinen et al.   MOLECULAR IMMUNOLOGY

Borrelia burgdorferi Infection-Associated Surface Proteins ErpP, ErpA, and ErpC Bind Human Plasminogen

(2008) C. A. Brissette et al.   INFECTION AND IMMUNITY

Assessment of the regions within complement regulator-acquiring surface protein (CRASP)-2 of Borrelia burgdorferi required for interaction with host immune regulators FHL-1 and factor H

(2008) Peter Kraiczy et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Identification and characterization of the factor H and FHL-1 binding complement regulator-acquiring surface protein 1 of the Lyme disease spirochete Borrelia spielmanii sp. nov.

(2008) P HERZBERGER et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Deciphering the Ligand-binding Sites in theBorrelia burgdorferiComplement Regulator-acquiring Surface Protein 2 Required for Interactions with the Human Immune Regulators Factor H and Factor H-like Protein 1

(2008) Corinna Siegel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Detection of Borrelia bissettii in Cardiac Valve Tissue of a Patient with Endocarditis and Aortic Valve Stenosis in the Czech Republic

(2008) N. Rudenko et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Complement evasion by human pathogens

(2008) John D. Lambris et al.   NATURE REVIEWS MICROBIOLOGY

Borrelia burgdorferi Complement Regulator-Acquiring Surface Protein 2 Does Not Contribute to Complement Resistance or Host Infectivity

(2008) Adam S. Coleman et al.   PLoS One