Lifestyle changes for the treatment of nonalcoholic fatty liver disease: a review of observational studies and intervention trials

Targeting gut-liver axis for the treatment of nonalcoholic steatohepatitis: translational and clinical evidence

(2016) Alessandro Federico et al.   Translational Research

Soft Drink Consumption Linked with Fatty Liver in the Absence of Traditional Risk Factors

(2016) Nimer Assy et al.   CANADIAN JOURNAL OF GASTROENTEROLOGY

Mediterranean diet and non-alcoholic fatty liver disease

(2015) Francesca M. Trovato et al.   CLINICAL NUTRITION

Weight Loss Through Lifestyle Modification Significantly Reduces Features of Nonalcoholic Steatohepatitis

(2015) Eduardo Vilar-Gomez et al.   GASTROENTEROLOGY

Association of Coffee Intake With Reduced Incidence of Liver Cancer and Death From Chronic Liver Disease in the US Multiethnic Cohort

(2015) Veronica Wendy Setiawan et al.   GASTROENTEROLOGY

Moderate to vigorous physical activity volume is an important factor for managing nonalcoholic fatty liver disease: A retrospective study

(2015) Sechang Oh et al.   HEPATOLOGY

Relationship of sitting time and physical activity with non-alcoholic fatty liver disease

(2015) Seungho Ryu et al.   JOURNAL OF HEPATOLOGY

Incidence of non-alcoholic fatty liver disease in Hong Kong: A population study with paired proton-magnetic resonance spectroscopy

(2015) Vincent Wai-Sun Wong et al.   JOURNAL OF HEPATOLOGY

Sugar-sweetened beverage, diet soda, and fatty liver disease in the Framingham Heart Study cohorts

(2015) Jiantao Ma et al.   JOURNAL OF HEPATOLOGY

Effect of aerobic exercise training dose on liver fat and visceral adiposity

(2015) Shelley E. Keating et al.   JOURNAL OF HEPATOLOGY

Effects of n-3 fish oil on metabolic and histological parameters in NASH: A double-blind, randomized, placebo-controlled trial

(2015) Curtis K. Argo et al.   JOURNAL OF HEPATOLOGY

The association between the serum levels of uric acid and alanine aminotransferase in a population-based cohort

(2015) Shira Zelber-Sagi et al.   LIVER INTERNATIONAL

Coffee consumption and nonalcoholic fatty liver onset: a prospective study in the general population

(2015) Shira Zelber-Sagi et al.   Translational Research

Association of daily coffee and tea consumption and metabolic syndrome: results from the Polish arm of the HAPIEE study

(2014) Giuseppe Grosso et al.   EUROPEAN JOURNAL OF NUTRITION

No Significant Effects of Ethyl-Eicosapentanoic Acid on Histologic Features of Nonalcoholic Steatohepatitis in a Phase 2 Trial

(2014) Arun J. Sanyal et al.   GASTROENTEROLOGY

Effects of purified eicosapentaenoic and docosahexaenoic acids in nonalcoholic fatty liver disease: Results from the WELCOME* study

(2014) Eleonora Scorletti et al.   HEPATOLOGY

Coffee components and cardiovascular risk: beneficial and detrimental effects

(2014) Justyna Godos et al.   INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION

Effect of resistance training on non-alcoholic fatty-liver disease a randomized-clinical trial

(2014) Shira Zelber-Sagi   WORLD JOURNAL OF GASTROENTEROLOGY

Effects of Aerobic Training, Resistance Training, or Both on Percentage Body Fat and Cardiometabolic Risk Markers in Obese Adolescents

(2014) Ronald J. Sigal et al.   JAMA Pediatrics

2013 AHA/ACC Guideline on Lifestyle Management to Reduce Cardiovascular Risk

(2013) Robert H. Eckel et al.   CIRCULATION

Mediterranean Diet and Cardiovascular Risk Factors: A Systematic Review

(2013) Giuseppe Grosso et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Both resistance training and aerobic training reduce hepatic fat content in type 2 diabetic subjects with nonalcoholic fatty liver disease (the RAED2 randomized trial)

(2013) Elisabetta Bacchi et al.   HEPATOLOGY

Caffeine attenuates liver fibrosis via defective adhesion of hepatic stellate cells in cirrhotic model

(2013) Sung Gon Shim et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Unconjugated bilirubin, a potent endogenous antioxidant, is decreased in patients with non-alcoholic steatohepatitis and advanced fibrosis

(2013) Federico Salomone et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

The Mediterranean diet improves hepatic steatosis and insulin sensitivity in individuals with non-alcoholic fatty liver disease

(2013) Marno C. Ryan et al.   JOURNAL OF HEPATOLOGY

Community-based lifestyle modification programme for non-alcoholic fatty liver disease: A randomized controlled trial

(2013) Vincent Wai-Sun Wong et al.   JOURNAL OF HEPATOLOGY

The I148M Variant of PNPLA3 Reduces the Response to Docosahexaenoic Acid in Children with Non-Alcoholic Fatty Liver Disease

(2013) Valerio Nobili et al.   JOURNAL OF MEDICINAL FOOD

Impact of coffee on liver diseases: a systematic review

(2013) Sammy Saab et al.   LIVER INTERNATIONAL

Non-high-density lipoprotein cholesterol independently predicts new onset of non-alcoholic fatty liver disease

(2013) Shira Zelber-Sagi et al.   LIVER INTERNATIONAL

Coffee consumption in NAFLD patients with lower insulin resistance is associated with lower risk of severe fibrosis

(2013) Kiran Bambha et al.   LIVER INTERNATIONAL

Coffee enhances the expression of chaperones and antioxidant proteins in rats with nonalcoholic fatty liver disease

(2013) Federico Salomone et al.   Translational Research

Genetic-related and carbohydrate-related factors affecting liver fat accumulation

(2012) Michael I. Goran et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Liver Fat Is Reduced by an Isoenergetic MUFA Diet in a Controlled Randomized Study in Type 2 Diabetic Patients

(2012) L. Bozzetto et al.   DIABETES CARE

Impact of current treatments on liver disease, glucose metabolism and cardiovascular risk in non-alcoholic fatty liver disease (NAFLD): a systematic review and meta-analysis of randomised trials

(2012) G. Musso et al.   DIABETOLOGIA

European Guidelines on cardiovascular disease prevention in clinical practice (version 2012): The Fifth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice (constituted by representatives of nine societies and by invited experts) * Developed with the special contribution of the European Association for Cardiovascular Prevention & Rehabilitation (EACPR)

(2012) et al.   EUROPEAN HEART JOURNAL

Consumption of n-3 Fatty Acids and Fish Reduces Risk of Hepatocellular Carcinoma

(2012) Norie Sawada et al.   GASTROENTEROLOGY

The diagnosis and management of non-alcoholic fatty liver disease: Practice Guideline by the American Association for the Study of Liver Diseases, American College of Gastroenterology, and the American Gastroenterological Association

(2012) Naga Chalasani et al.   HEPATOLOGY

Synergistic interaction of dietary cholesterol and dietary fat in inducing experimental steatohepatitis

(2012) Christopher Savard et al.   HEPATOLOGY

Predictors for incidence and remission of NAFLD in the general population during a seven-year prospective follow-up

(2012) Shira Zelber-Sagi et al.   JOURNAL OF HEPATOLOGY

Exercise and non-alcoholic fatty liver disease: A systematic review and meta-analysis

(2012) Shelley E. Keating et al.   JOURNAL OF HEPATOLOGY

Regular coffee but not espresso drinking is protective against fibrosis in a cohort mainly composed of morbidly obese European women with NAFLD undergoing bariatric surgery

(2012) Rodolphe Anty et al.   JOURNAL OF HEPATOLOGY

Nonalcoholic Fatty Liver Disease in Lean Individuals in the United States

(2012) Zobair M. Younossi et al.   MEDICINE

Hepatic Fat Accumulation Is Modulated by the Interaction between the rs738409 Variant in the PNPLA3 Gene and the Dietary Omega6/Omega3 PUFA Intake

(2012) Nicola Santoro et al.   PLoS One

Moroorange juice prevents fatty liver in mice

(2012) Federico Salamone   WORLD JOURNAL OF GASTROENTEROLOGY

Genetic variation in PNPLA3 (adiponutrin) confers sensitivity to weight loss-induced decrease in liver fat in humans

(2011) K. Sevastianova et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Sucrose-sweetened beverages increase fat storage in the liver, muscle, and visceral fat depot: a 6-mo randomized intervention study

(2011) Maria Maersk et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Short-term weight loss and hepatic triglyceride reduction: evidence of a metabolic advantage with dietary carbohydrate restriction

(2011) Jeffrey D Browning et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Physical Activity Recommendations, Exercise Intensity, and Histological Severity of Nonalcoholic Fatty Liver Disease

(2011) Kristin D Kistler et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Effects of aerobic vs. resistance training on visceral and liver fat stores, liver enzymes, and insulin resistance by HOMA in overweight adults from STRRIDE AT/RT

(2011) Cris A. Slentz et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Changes in the Prevalence of the Most Common Causes of Chronic Liver Diseases in the United States From 1988 to 2008

(2011) Zobair M. Younossi et al.   Clinical Gastroenterology and Hepatology

Silibinin improves hepatic and myocardial injury in mice with nonalcoholic steatohepatitis

(2011) Federico Salamone et al.   DIGESTIVE AND LIVER DISEASE

Resistance exercise reduces liver fat and its mediators in non-alcoholic fatty liver disease independent of weight loss

(2011) K. Hallsworth et al.   GUT

Association of coffee and caffeine consumption with fatty liver disease, nonalcoholic steatohepatitis, and degree of hepatic fibrosis

(2011) Jeffrey W. Molloy et al.   HEPATOLOGY

Randomized comparison of reduced fat and reduced carbohydrate hypocaloric diets on intrahepatic fat in overweight and obese human subjects

(2011) Sven Haufe et al.   HEPATOLOGY

Omega-3 supplementation and non-alcoholic fatty liver disease: A systematic review and meta-analysis

(2011) Helen M. Parker et al.   JOURNAL OF HEPATOLOGY

Lifestyle interventions for the treatment of non-alcoholic fatty liver disease in adults: A systematic review

(2011) Christian Thoma et al.   JOURNAL OF HEPATOLOGY

Increased hepatic fat in overweight Hispanic youth influenced by interaction between genetic variation in PNPLA3 and high dietary carbohydrate and sugar consumption

(2010) Jaimie N Davis et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Exercise and fat accumulation in the human liver

(2010) Faidon Magkos   CURRENT OPINION IN LIPIDOLOGY

Effects of short-term overfeeding with fructose, fat and fructose plus fat on plasma and hepatic lipids in healthy men

(2010) H. Sobrecases et al.   DIABETES & METABOLISM

Effect of a 12-Month Intensive Lifestyle Intervention on Hepatic Steatosis in Adults With Type 2 Diabetes

(2010) M. Lazo et al.   DIABETES CARE

The effects of aerobic exercise on metabolic risk, insulin sensitivity and intrahepatic lipid in healthy older people from the Hertfordshire Cohort Study: a randomised controlled trial

(2010) F. M. Finucane et al.   DIABETOLOGIA

Increased fructose consumption is associated with fibrosis severity in patients with nonalcoholic fatty liver disease

(2010) Manal F. Abdelmalek et al.   HEPATOLOGY

Coffee reduces liver damage in a rat model of steatohepatitis: The underlying mechanisms and the role of polyphenols and melanoidins

(2010) Paola Vitaglione et al.   HEPATOLOGY

Association between serum uric acid level and chronic liver disease in the United States

(2010) Anita Afzali et al.   HEPATOLOGY

A position statement on NAFLD/NASH based on the EASL 2009 special conference

(2010) Vlad Ratziu et al.   JOURNAL OF HEPATOLOGY

High Serum Uric Acid Increases the Risk for Nonalcoholic Fatty Liver Disease: A Prospective Observational Study

(2010) Chengfu Xu et al.   PLoS One

Fructose overconsumption causes dyslipidemia and ectopic lipid deposition in healthy subjects with and without a family history of type 2 diabetes

(2009) Kim-Anne Lê et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Effect of Body Weight and Lifestyle Changes on Long-Term Course of Nonalcoholic Fatty Liver Disease in Koreans

(2009) Hong-Kyu Kim et al.   AMERICAN JOURNAL OF THE MEDICAL SCIENCES

Dietary Fat and Carbohydrates Differentially Alter Insulin Sensitivity During Caloric Restriction

(2009) Erik Kirk et al.   GASTROENTEROLOGY

Weight gain within the normal weight range predicts ultrasonographically detected fatty liver in healthy Korean men

(2009) Y Chang et al.   GUT

Randomized controlled trial testing the effects of weight loss on nonalcoholic steatohepatitis

(2009) Kittichai Promrat et al.   HEPATOLOGY

Association between dietary nutrient composition and the incidence of cirrhosis or liver cancer in the united states population

(2009) George N. Ioannou et al.   HEPATOLOGY

Aerobic exercise training reduces hepatic and visceral lipids in obese individuals without weight loss

(2009) Nathan A. Johnson et al.   HEPATOLOGY

A pilot trial of body weight reduction for nonalcoholic fatty liver disease with a home-based lifestyle modification intervention delivered in collaboration with interdisciplinary medical staff

(2009) Noriko Oza et al.   JOURNAL OF GASTROENTEROLOGY

Soft drink consumption is associated with fatty liver disease independent of metabolic syndrome

(2009) Ali Abid et al.   JOURNAL OF HEPATOLOGY

Weight-Loss Diets for the Prevention and Treatment of Obesity

(2009) Martijn B. Katan   NEW ENGLAND JOURNAL OF MEDICINE

Diet and Exercise Interventions Reduce Intrahepatic Fat Content and Improve Insulin Sensitivity in Obese Older Adults

(2009) Krupa Shah et al.   Obesity

A 12-Week Aerobic Exercise Program Reduces Hepatic Fat Accumulation and Insulin Resistance in Obese, Hispanic Adolescents

(2009) Gert-Jan van der Heijden et al.   Obesity

Development of hyperinsulinemia and insulin resistance during the early stage of weight gain

(2008) Johannes Erdmann et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Hepatotoxicity of fast food?

(2008) G. Marchesini et al.   GUT

Fast-food-based hyper-alimentation can induce rapid and profound elevation of serum alanine aminotransferase in healthy subjects

(2008) S. Kechagias et al.   GUT

Health-related fitness and physical activity in patients with nonalcoholic fatty liver disease

(2008) Joanne B. Krasnoff et al.   HEPATOLOGY

Role of leisure-time physical activity in nonalcoholic fatty liver disease: A population-based study

(2008) Shira Zelber-Sagi et al.   HEPATOLOGY

Orlistat for overweight subjects with nonalcoholic steatohepatitis: A randomized, prospective trial

(2008) Stephen A. Harrison et al.   HEPATOLOGY

Dietary cholesterol, rather than liver steatosis, leads to hepatic inflammation in hyperlipidemic mouse models of nonalcoholic steatohepatitis

(2008) Kristiaan Wouters et al.   HEPATOLOGY

Large Artery Stiffening With Weight Gain in Humans

(2008) Jeb S. Orr et al.   HYPERTENSION

Effect of a lifestyle intervention in patients with abnormal liver enzymes and metabolic risk factors

(2008) Alexis St. George et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Antibiotics protect against fructose-induced hepatic lipid accumulation in mice: Role of endotoxin

(2008) Ina Bergheim et al.   JOURNAL OF HEPATOLOGY

Fructose consumption as a risk factor for non-alcoholic fatty liver disease

(2008) Xiaosen Ouyang et al.   JOURNAL OF HEPATOLOGY

Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease

(2008) Stefano Romeo et al.   NATURE GENETICS

Nutritional investigation of non-obese patients with non-alcoholic fatty liver disease: The significance of dietary cholesterol

(2008) Kenichiro Yasutake et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY