Cordycepin inhibits LPS-induced inflammatory and matrix degradation in the intervertebral disc

Suppressing effect of cordycepin on the lipopolysaccharide-induced nitric oxide production in RAW 264.7 cells

(2015) Kenta Imamura et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Proinflammatory cytokines modulate the chemokine CCL2 (MCP-1) in human annulus cells in vitro: CCL2 expression and production

(2015) Helen E. Gruber et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Anticancer and antimetastatic effects of cordycepin, an active component of Cordyceps sinensis

(2015) Kazuki Nakamura et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Inflammatory Kinetics and Efficacy of Anti-inflammatory Treatments on Human Nucleus Pulposus Cells

(2015) Benjamin A. Walter et al.   SPINE

Fibrin-genipin annulus fibrosus sealant as a delivery system for anti-TNFα drug

(2015) Morakot Likhitpanichkul et al.   Spine Journal

Intervention of rAAV-hTERT-Transducted Nucleus Pulposus Cells in Early Stage of Intervertebral Disc Degeneration: A Study in Canine Model

(2015) Zhiyuan Shi et al.   TISSUE ENGINEERING PART A

TGF-βl Suppresses Inflammation in Cell Therapy for Intervertebral Disc Degeneration

(2015) Huilin Yang et al.   Scientific Reports

Oxidative stress participates in age-related changes in rat lumbar intervertebral discs

(2014) Gang Hou et al.   ARCHIVES OF GERONTOLOGY AND GERIATRICS

Expression and regulation of toll-like receptors (TLRs) in human intervertebral disc cells

(2014) Marina Klawitter et al.   EUROPEAN SPINE JOURNAL

High mechanical strain of primary intervertebral disc cells promotes secretion of inflammatory factors associated with disc degeneration and pain

(2014) Rahul Gawri et al.   ARTHRITIS RESEARCH & THERAPY

Lactoferricin mediates anti-inflammatory and anti-catabolic effects via inhibition of IL-1 and LPS activity in the intervertebral disc

(2013) Jae-Sung Kim et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Variations in Gene and Protein Expression in Canine Chondrodystrophic Nucleus Pulposus Cells following Long-Term Three-Dimensional Culture

(2013) Munetaka Iwata et al.   PLoS One

Inhibition of Nitric Oxide Mediated Protein Nitration

(2013) Seong Jae Lee et al.   SPINE

Tumor Necrosis Factor-α-Dependent Infiltration of Macrophages Into the Dorsal Root Ganglion in a Rat Disc Herniation Model

(2013) Changcheng You et al.   SPINE

Expression and regulation of metalloproteinases and their inhibitors in intervertebral disc aging and degeneration

(2013) Nam V. Vo et al.   Spine Journal

The molecular basis of intervertebral disc degeneration

(2013) Christopher K. Kepler et al.   Spine Journal

Intervertebral disc and macrophage interaction induces mechanical hyperalgesia and cytokine production in a herniated disc model in rats

(2012) Toru Takada et al.   ARTHRITIS AND RHEUMATISM

Tumor necrosis factor α- and interleukin-1β-dependent induction of CCL3 expression by nucleus pulposus cells promotes macrophage migration through CCR1

(2012) Jianru Wang et al.   ARTHRITIS AND RHEUMATISM

Toll-like receptor adaptor signaling molecule MyD88 on intervertebral disk homeostasis: In vitro, ex vivo studies

(2012) Michael B. Ellman et al.   GENE

Cordycepin suppresses TNF-α-induced NF-κB activation by reducing p65 transcriptional activity, inhibiting IκBα phosphorylation, and blocking IKKγ ubiquitination

(2012) Zhenghua Ren et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

The genusCordyceps: a chemical and pharmacological review

(2012) Kai Yue et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Toll-Like Receptor 4 (TLR4) Expression and Stimulation in a Model of Intervertebral Disc Inflammation and Degeneration

(2012) Neena E. Rajan et al.   SPINE

Effect of Hyperbaric Oxygenation on Intervertebral Disc Degeneration

(2011) I-Chun Wang et al.   SPINE

Injection of AAV2-BMP2 and AAV2-TIMP1 into the nucleus pulposus slows the course of intervertebral disc degeneration in an in vivo rabbit model

(2011) Steven K. Leckie et al.   Spine Journal

Anti-inflammatory effects of cordycepin via suppression of inflammatory mediators in BV2 microglial cells

(2010) Jin-Woo Jeong et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Cordycepin induces apoptosis by enhancing JNK and p38 kinase activity and increasing the protein expression of Bcl-2 pro-apoptotic molecules

(2010) Wei He et al.   Journal of Zhejiang University-SCIENCE B

Cordycepin suppresses TNF-alpha-induced invasion, migration and matrix metalloproteinase-9 expression in human bladder cancer cells

(2010) Eo-Jin Lee et al.   PHYTOTHERAPY RESEARCH

Modified expression of the ADAMTS enzymes and tissue inhibitor of metalloproteinases 3 during human intervertebral disc degeneration

(2009) Aneta J. Pockert et al.   ARTHRITIS AND RHEUMATISM

Matrix metalloproteinase expression levels suggest distinct enzyme roles during lumbar disc herniation and degeneration

(2009) Beatrice E. Bachmeier et al.   EUROPEAN SPINE JOURNAL

Analyzing real-time PCR data by the comparative CT method

(2008) Thomas D Schmittgen et al.   Nature Protocols

Cordyceps – A traditional Chinese medicine and another fungal therapeutic biofactory?

(2008) R. Russell M. Paterson   PHYTOCHEMISTRY