Article
Agriculture, Multidisciplinary
Xin Fu, Xin-Yi Zan, Lei Sun, Ming Tan, Feng-Jie Cui, Ying-Ying Liang, Li-Juan Meng, Wen-Jing Sun
Summary: In this study, the gene CMGLS encoding the membrane-bound beta-1,3-glucan synthase CMGLS in Cordyceps militaris was cloned and analyzed. The three-dimensional structure of CMGLS and its binding features with substrate UDP-glucose were proposed for the first time. These findings provide insights into the glucan synthesis process and catalytic mechanism of beta-1,3-glucan synthases in mushrooms.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2022)
Article
Food Science & Technology
Chunmei Gu, Debin Zhang, Wenjiao Zhai, Huipeng Zhang, Sida Wang, Siyao Lv, Yunxiang Bao, Dengzhao Zhu, Shangcai Feng, Shaofen Guo, Zhen Wang
Summary: Cordyceps militaris is a significant medicinal and edible fungus, with polysaccharides playing a key role in its pharmacological functions. Recent research has focused on the molecular structure and pharmacological mechanism of its polysaccharides, as well as addressing issues such as low yield and poor functions in industrial production.
Article
Biochemistry & Molecular Biology
Yefei Liu, Kun Xiao, Ze Wang, Shenghou Wang, Fangxu Xu
Summary: The study compared the chemical composition of Cordyceps sinensis and Cordyceps militaris, revealing that the latter has significant advantages in multiple metabolic pathways. This suggests that Cordyceps militaris cultivated with tussah pupa could partially substitute high-priced Cordyceps sinensis. The results provide theoretical basis and scientific support for clinical practice.
JOURNAL OF FOOD BIOCHEMISTRY
(2021)
Article
Biochemistry & Molecular Biology
Yuan Li, Miao Miao, Fan Yin, Nuo Shen, Wen-Qian Yu, Shou-Dong Guo
Summary: A polysaccharide-peptide complex called CMPS-80 obtained from C. militaris was found to significantly improve atherosclerotic lesions and lipid profiles in mice lacking apolipoprotein E. Informatics analysis suggested that CMPS-80 can modulate multiple lncRNA-microRNA-mRNA axes. CMPS-80 has the potential to be used for prevention of hyperlipidemia and atherosclerosis.
Article
Chemistry, Multidisciplinary
Gen Zou, Bo Li, Ying Wang, Xin Yin, Ming Gong, Junjun Shang, Yongjun Wei, Xiaoling Li, Dapeng Bao
Summary: Engineered Cordyceps militaris can convert spent mushroom substrate (SMS) into the anticancer drug pentostatin, utilizing lignocellulosic waste for high-value product biosynthesis. Featuring strong hydrolytic activity towards cellulose and increased pentostatin production, this biological strategy offers a sustainable solution for SMS pollution removal while producing valuable bioactive compounds.
Article
Biochemistry & Molecular Biology
Qiaoying Song, Yaqi Li, Yunqin Jia, Lichao Pan, Zhen-yuan Zhu
Summary: Domesticated Cordyceps militaris exhibited a better response mechanism to Pb2+ stress with higher GSH content, biomass level, and critical enzyme activity. It showed a better ability in alleviating oxidative stress and poisoning caused by Pb2+.
PROCESS BIOCHEMISTRY
(2021)
Article
Plant Sciences
Yang Ji, Tianyi Tao, Junmiao Zhang, Anxiang Su, Liyan Zhao, Hui Chen, Qiuhui Hu
Summary: Ophiocordyceps sinensis showed better outcomes in attenuating colitis-associated tumorigenesis in mice compared to Cordyceps militaris, potentially due to its promotion of probiotic growth and modulation of the Wnt/beta-catenin signaling pathway. FMT and antibiotic treatment further supported the alleviating effects of O. sinensis on colonic inflammation and tumorigenesis.
Article
Biotechnology & Applied Microbiology
Yi Zhao, Shu-Li Li, Hai-Ying Chen, Yuan Zou, Qian-Wang Zheng, Li-Qiong Guo, Guang-Hong Wu, Jun Lu, Jun-Fang Lin, Zhi-Wei Ye
Summary: The study investigated the effects of oxidative and osmotic stress on the morphology and carotenoid accumulation of Cordyceps militaris, revealing significant impact on carotenoid accumulation under oxidative stress conditions, with genes in the MAPK signaling pathway playing important roles.
ENZYME AND MICROBIAL TECHNOLOGY
(2021)
Article
Food Science & Technology
Sujarinee Sangwanna, Weerasak Seelarat, Teerapap Panklai, Natthaphon Chaosuan, Ahkasit Subcharoen, Nuttapon Subcharoen, Nattapong Chanchula, Tanapak Inyod, Thanaphat Toemarrom, Atipong Bootchanont, Chakkaphan Wattanawikkam, Sorapong Pavasupree, Dheerawan Boonyawan, Porramain Porjai
Summary: This study investigated the effects of different treatment times of an air atmospheric pressure plasma jet (APPJ) on the production of fruiting bodies and phytochemicals of white Cordyceps militaris. Results showed that optimal APPJ treatment significantly increased the fresh and dry weights of white C. militaris fruiting bodies. APPJ treatments also led to higher levels of cordycepin, adenosine, superoxide dismutase, glutathione S-transferase, and beta-glucan in the fruiting bodies, as well as enhanced antioxidant properties. However, carotenoid content decreased with APPJ treatment.
FOOD AND BIOPROCESS TECHNOLOGY
(2023)
Article
Food Science & Technology
Farouq Heidar Barido, Sun Moon Kang, Sung Ki Lee
Summary: This study aimed to investigate the functional and quality improvement of retorted Korean ginseng chicken soup that was hydrolyzed using a single extract from Cordyceps militaris (CM) mushroom, or in combination with bromelain, flavorzyme, or a mix of both. The highest antioxidant activity and tenderization effect were observed in the samples treated with a mixture of CM extract and bromelain. The improvement in taste properties was attributed to the increase of umami substances, such as 5'-nucleotides and free amino acids.
Article
Environmental Sciences
Wangkheimayum Malemnganbi Devi, Himadri Saha, Surajkumar Irungbam, Ratan Kumar Saha
Summary: The study investigated the use of Cordyceps militaris spent mushroom substrate (CMSMS) as an alternative to in-feed antibiotics for fish. The results showed that a dose of 30g/kg of CMSMS had a better immune response and improved survival rate in Labeo rohita fish. This suggests that CMSMS can be safely used as an in-feed antibiotic in fish and can reduce concerns related to by-product disposal from mushroom cultivation.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Biochemistry & Molecular Biology
Yue Yu, Qiang Wen, Ao Song, Yang Liu, Fei Wang, Bin Jiang
Summary: AESP-II is an acidic polysaccharide that promotes immune cell proliferation and increases immunoglobulin levels, mediated through the activation of the MAPK signaling pathway.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Biochemistry & Molecular Biology
HuiQing Sun, XiaoFeng Yu, Ting Li, ZhenYuan Zhu
Summary: A novel neutral exopolysaccharide (EPS-III) was isolated from Cordyceps militaris culture, with its structure and hypoglycemic activity studied in this research, proving its potential application value in lowering blood sugar and protecting immune organs.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Engineering, Chemical
Weerasak Seelarat, Sujarinee Sangwanna, Teerapap Panklai, Natthaphon Chaosuan, Atipong Bootchanont, Chakkaphan Wattanawikkam, Ahkasit Subcharoen, Nuttapon Subcharoen, Nattapong Chanchula, Dheerawan Boonyawan, Porramain Porjai
Summary: The impact of cold plasma jet on fruiting body production and bioactive phytochemicals in blended Cordyceps militaris was evaluated. The results showed that CPJ treatment significantly increased the yield and nutritional value of blended C. militaris.
PLASMA CHEMISTRY AND PLASMA PROCESSING
(2023)
Article
Immunology
Qian Meng, Pei-Pei Wu, Miao-Miao Li, Rui-Hao Shu, Gui-Ling Zhou, Ji-Hong Zhang, Huan Zhang, Haobo Jiang, Qi-Lian Qin, Zhen Zou
Summary: Melanization and encapsulation are important defense responses against microbes in host insects. In the ghost moth Thitarodes xiaojinensis, the proteins beta GRP1 and IML8 play crucial roles in modulating immune responses, while O. sinensis may evade melanization by preventing beta GRP1 recognition.
JOURNAL OF IMMUNOLOGY
(2021)
Article
Forestry
Shu Liao, Kai Yue, Xiangyin Ni, Fuzhong Wu
Summary: This study found that acid hydrolysable components in plant litter are released not only in the early stages of decomposition but also in the very late stages. The content of these components significantly increased at the snowmelt stages. Reduced snow cover increased their content and remaining level during the four years of decomposition by altering leaching, microbial biomass, and stoichiometry. Therefore, considering the effects of changing environmental factors on chemical partitioning is important in studying litter decomposition.
Article
Biology
Kai Yue, Pieter De Frenne, Koenraad Van Meerbeek, Veronica Ferreira, Dario A. Fornara, Qiqian Wu, Xiangyin Ni, Yan Peng, Dingyi Wang, Petr Hedenec, Yusheng Yang, Fuzhong Wu, Josep Penuelas
Summary: Invertebrates contribute significantly to stream litter decomposition, with their effects influenced by initial litter quality and stream water physicochemical properties. Climate region, mesh size, and mycorrhizal association have minimal impact on invertebrate effects. Invertebrate contribution is highest during the early stages of litter mass loss.
BIOLOGICAL REVIEWS
(2022)
Article
Ecology
Yan Peng, Josep Penuelas, Lars Vesterdal, Kai Yue, Guille Peguero, Dario A. Fornara, Petr Hedenec, Christina Steffens, Fuzhong Wu
Summary: Soil fauna density and diversity are minimally affected by individual and combined effects of global change factors, except for drought negatively impacting density and increased rainfall, nitrogen addition, and warming positively impacting density. The effects vary among taxonomic groups and are influenced by variables such as latitude, elevation, and experimental setting.
Article
Biodiversity Conservation
Qiqian Wu, Kai Yue, Yuandan Ma, Petr Hedenec, Yanjiang Cai, Jian Chen, Hui Zhang, Junjiong Shao, Scott X. Chang, Yan Li
Summary: Changes in precipitation regimes have different effects on soil nitrogen cycling in arid and humid regions. Increased precipitation leads to higher nitrogen input and output but lower nitrogen storage, while decreased precipitation has the opposite effect. Arid regions are more sensitive to increased precipitation, while humid regions are more sensitive to decreased precipitation.
GLOBAL CHANGE BIOLOGY
(2022)
Article
Agronomy
Jingjing Zhu, Qiuxia Wu, Fuzhong Wu, Kai Yue, Xiangyin Ni
Summary: This study investigated the release of different carbon fractions during decomposition of fir and birch litter with and without snow cover. The results showed that a significant amount of organic carbon was lost from both types of litter, with a higher decomposition rate under snow cover. The release of O-alkyl C, particularly carbohydrate C, was reduced with snow removal, while the release of other carbon fractions remained unchanged.
Article
Agronomy
Yan Peng, Chaoxiang Yuan, Petr Hedenec, Kai Yue, Guiqing Zhu, Xia Jin, Qiao Yang, Shuyuan Wei, Fuzhong Wu
Summary: The transforming of different ecosystem types to tree plantation has significant effects on soil carbon, nitrogen, and phosphorus concentrations. Transforming croplands, deserts, and grasslands to plantations increases soil C, N, and/or P concentrations, while transforming primary and secondary forests to plantations has opposite effects.
Article
Environmental Sciences
Qiao Yang, Kai Yue, Fuzhong Wu, Petr Hedenec, Xiangyin Ni, Dingyi Wang, Ji Yuan, Jimei Yu, Yan Peng
Summary: Ash is an important component of plant litter and its concentration plays a crucial role in litter decomposition. This study assessed the global patterns of initial litter ash concentrations and identified the effects of mycorrhizal association, taxon group, life form, leaf type, and environmental factors on litter ash concentration. The results showed significant variation in ash concentrations among different plant tissues and highlighted the importance of mycorrhizal association and taxon group in determining litter ash concentrations.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Plant Sciences
Yan Peng, Ji Yuan, Petr Hedenec, Kai Yue, Xiangyin Ni, Wang Li, Dingyi Wang, Chaoxiang Yuan, Siyi Tan, Fuzhong Wu
Summary: By quantitatively assessing the global patterns and drivers of litter initial concentrations of lignin, cellulose, and hemicellulose, this study found that these concentrations are regulated by phylogeny, plant functional type, climate, and soil properties, with mycorrhizal association and lifeform being the dominant predictors.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Limnology
Zemin Zhao, Fuzhong Wu, Yan Peng, Petr Hedenec, Yuan Wang, Wanrong Hu, Xiangyin Ni, Kai Yue
Summary: This study assessed the temporal and spatial storage dynamics of several common heavy metals in the fine sediments of a subtropical forest headwater stream. The results showed that the storage of heavy metals varied across different temporal and spatial scales, and the key factors controlling their storage were water alkalinity, temperature, pH, and monthly precipitation. These findings enhance our understanding of the role of headwater streams in storing and transferring materials in forest ecosystems.
Article
Multidisciplinary Sciences
Xia Jin, Fuzhong Wu, Qiqian Wu, Petr Hedenec, Yan Peng, Zheng Wang, Kai Yue
Summary: Irregular precipitation caused by climate changes has resulted in frequent events of soil drying-rewetting cycles (DWC), which can strongly affect soil carbon (C) and nitrogen (N) cycling, including the fluxes of greenhouse gases (GHGs). However, the quantitative assessment of the response of soil carbon dioxide (CO2), methane (CH4), and nitrous oxide (N2O) fluxes to DWC events in different ecosystems is lacking.
Article
Ecology
Haifeng Zheng, Richard P. Phillips, Johannes Rousk, Kai Yue, Inger Kappel Schmidt, Yan Peng, Senhao Wang, Lars Vesterdal
Summary: Understanding the effects of tree species and their mycorrhizal association on soil processes is crucial for predicting the consequences of species shifts and forest management decisions. The activity of soil enzymes and enzymatic stoichiometry play critical roles in shaping the differences in the nutrient economy between different mycorrhizal tree species.
FUNCTIONAL ECOLOGY
(2023)
Review
Ecology
Xinyu Wei, Koenraad Van Meerbeek, Kai Yue, Xiangyin Ni, Ellen Desie, Petr Hedenec, Jing Yang, Fuzhong Wu
Summary: Global warming and altered precipitation have significant effects on soil carbon pools. A meta-analysis of 657 observations from 34 published articles revealed that combined warming and increased precipitation led to an average increase in soil organic carbon (SOC) and microbial biomass carbon (MBC) by 4.0% and 15.4%, respectively. However, combined warming and decreased precipitation resulted in an average decline in SOC and MBC by 8.2% and 12.3%, respectively. The responses were influenced by the magnitude of altered precipitation.
GLOBAL ECOLOGY AND BIOGEOGRAPHY
(2023)
Article
Agronomy
Chaoxiang Yuan, Fuzhong Wu, Yan Peng, Qiqian Wu, Guiqing Zhu, Zemin Zhao, Yiqing Wang, Nannan An, Xiangyin Ni, Kai Yue
Summary: The aim of this study was to assess the impact of afforestation on soil pH at a global scale. By analyzing data from 2642 paired observations, we found that afforestation led to a significant decrease in soil pH, with the effects varying depending on the type of afforestation. Additionally, the driving factors behind these effects were identified, including plantation type, mycorrhizal association, and land use type.
Article
Forestry
Pingping Lian, Linglin Xu, Kai Yue, Liuming Yang
Summary: Exclusion of roots and mycorrhizal hyphae leads to a decrease in available carbon and nitrogen in the soil, resulting in a loss of microbial diversity. The exclusion of roots and mycorrhizal hyphae also alters the composition and function of the soil microbial community, thereby impacting microbial-driven nutrient cycling processes.
Article
Environmental Sciences
Qiqi Li, Chaoxiang Yuan, Qiqian Wu, Yan Peng, Zemin Zhao, Yiqing Wang, Nannan An, Xiangyin Ni, Fuzhong Wu, Kai Yue
Summary: Vegetation restoration has a positive effect on the concentrations of nutrient elements in post-mining soils, but does not influence the concentrations of toxic elements. Vegetation type and soil depth have some impact on the vegetation restoration effects, while latitude, elevation, restoration year, climate, and initial soil properties are also important moderator variables.
JOURNAL OF ENVIRONMENTAL MANAGEMENT
(2023)
