High mechanical strain of primary intervertebral disc cells promotes secretion of inflammatory factors associated with disc degeneration and pain

Cartilaginous constructs using primary chondrocytes from continuous expansion culture seeded in dense collagen gels

(2013) D.H. Rosenzweig et al.   Acta Biomaterialia

A role for TNFα in intervertebral disc degeneration: A non-recoverable catabolic shift

(2013) D. Purmessur et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Epigenetic transcriptional activation of monocyte chemotactic protein 3 contributes to long-lasting neuropathic pain

(2013) Satoshi Imai et al.   BRAIN

Do Changing Toll-like Receptor Profiles in Different Layers and Grades of Osteoarthritis Cartilage Reflect Disease Severity?

(2013) G. Barreto et al.   JOURNAL OF RHEUMATOLOGY

Expression and Relationship of Proinflammatory Chemokine RANTES/CCL5 and Cytokine IL-1β in Painful Human Intervertebral Discs

(2013) Christopher K. Kepler et al.   SPINE

Functionalization of dynamic culture surfaces with a cartilage extracellular matrix extract enhances chondrocyte phenotype against dedifferentiation

(2012) Derek H. Rosenzweig et al.   Acta Biomaterialia

Low frequency mechanical stimulation inhibits adipogenic differentiation of C3H10T1/2 mesenchymal stem cells

(2012) Ghazaleh Khayat et al.   DIFFERENTIATION

Culture of Primary Bovine Chondrocytes on a Continuously Expanding Surface Inhibits Dedifferentiation

(2012) Derek H. Rosenzweig et al.   TISSUE ENGINEERING PART A

Toll-like receptor 2/MyD88 signaling mediates zymosan-induced joint hypernociception in mice: Participation of TNF-α, IL-1β and CXCL1/KC

(2011) Ana T.G. Guerrero et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Cyclic stretch-induced apoptosis in rat annulus fibrosus cells is mediated in part by endoplasmic reticulum stress through nitric oxide production

(2011) Yue-Hui Zhang et al.   EUROPEAN SPINE JOURNAL

Response of chondrocytes to shear stress: antagonistic effects of the binding partners Toll-like receptor 4 and caveolin-1

(2011) Pu Wang et al.   FASEB JOURNAL

TNF-α and IL-1β Promote a Disintegrin-like and Metalloprotease with Thrombospondin Type I Motif-5-mediated Aggrecan Degradation through Syndecan-4 in Intervertebral Disc

(2011) Jianru Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Spinal TLR4 mediates the transition to a persistent mechanical hypersensitivity after the resolution of inflammation in serum-transferred arthritis

(2011) Christina A. Christianson et al.   PAIN

Development of an Organ Culture System for Long-Term Survival of the Intact Human Intervertebral Disc

(2011) Rahul Gawri et al.   SPINE

Development of a Bioreactor for Axially Loaded Intervertebral Disc Organ Culture

(2011) Lisbet Haglund et al.   TISSUE ENGINEERING PART C-METHODS

The rat intervertebral disk degeneration pain model: relationships between biological and structural alterations and pain

(2011) Jae-Sung Kim et al.   ARTHRITIS RESEARCH & THERAPY

The involvement of interleukin-1 and interleukin-4 in the response of human annulus fibrosus cells to cyclic tensile strain: an altered mechanotransduction pathway with degeneration

(2011) Hamish TJ Gilbert et al.   ARTHRITIS RESEARCH & THERAPY

The response of human anulus fibrosus cells to cyclic tensile strain is frequency-dependent and altered with disc degeneration

(2010) Hamish T. J. Gilbert et al.   ARTHRITIS AND RHEUMATISM

Validation of the Cat as a Model for the Human Lumbar Spine During Simulated High-Velocity, Low-Amplitude Spinal Manipulation

(2010) Joel G. Pickar   JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME

Interleukin-1β induces angiogenesis and innervation in human intervertebral disc degeneration

(2010) Jae Man Lee et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Alterations in gene expression in response to compression of nucleus pulposus cells

(2010) Gwendolyn A. Sowa et al.   Spine Journal

Regulation of catabolic gene expression in normal and degenerate human intervertebral disc cells: implications for the pathogenesis of intervertebral disc degeneration

(2009) S Jane Millward-Sadler et al.   ARTHRITIS RESEARCH & THERAPY

Effects of cyclic strain on endothelial cell apoptosis and tubulogenesis are dependent on ROS production via NAD(P)H subunit p22phox

(2008) Baijun Kou et al.   MICROVASCULAR RESEARCH

A Novel Method of Dynamic Culture Surface Expansion Improves Mesenchymal Stem Cell Proliferation and Phenotype

(2008) Hicham Majd et al.   STEM CELLS

Proteomic analysis of the LPS-induced stress response in rat chondrocytes reveals induction of innate immune response components in articular cartilage

(2007) Lisbet Haglund et al.   MATRIX BIOLOGY

TLR4 signaling induces functional nerve growth factor receptor p75NTR on mouse dendritic cells via p38MAPK and NF-κB pathways

(2007) Yingming Jiang et al.   MOLECULAR IMMUNOLOGY