Lipid Nanovectors to Deliver RNA Oligonucleotides in Cancer

PEGylation as a strategy for improving nanoparticle-based drug and gene delivery

(2016) Jung Soo Suk et al.   ADVANCED DRUG DELIVERY REVIEWS

Development of edge-activated liposomes for siRNA delivery to human basal epidermis for melanoma therapy

(2016) Mania Dorrani et al.   JOURNAL OF CONTROLLED RELEASE

One-step encapsulation of siRNA between lipid-layers of multi-layer polycation liposomes by lipoplex freeze-thawing

(2016) Hiroyuki Koide et al.   JOURNAL OF CONTROLLED RELEASE

In vivo delivery of miRNAs for cancer therapy: Challenges and strategies

(2015) Yunching Chen et al.   ADVANCED DRUG DELIVERY REVIEWS

siRNA Delivery by Stimuli-Sensitive Nanocarriers

(2015) Giuseppina Salzano et al.   CURRENT PHARMACEUTICAL DESIGN

Lipid-Based Nanocarriers for RNA Delivery

(2015) Hui Xue et al.   CURRENT PHARMACEUTICAL DESIGN

Novel antisense therapeutics delivery systems: In vitro and in vivo studies of liposomes targeted with anti-CD20 antibody

(2015) Justyna M. Meissner et al.   JOURNAL OF CONTROLLED RELEASE

MiRNA-21 silencing mediated by tumor-targeted nanoparticles combined with sunitinib: A new multimodal gene therapy approach for glioblastoma

(2015) Pedro M. Costa et al.   JOURNAL OF CONTROLLED RELEASE

siRNA delivery to lung-metastasized tumor by systemic injection with cationic liposomes

(2015) Yoshiyuki Hattori et al.   JOURNAL OF LIPOSOME RESEARCH

Multifunctional Polymeric Micelles Co-loaded with Anti-Survivin siRNA and Paclitaxel Overcome Drug Resistance in an Animal Model of Ovarian Cancer

(2015) G. Salzano et al.   MOLECULAR CANCER THERAPEUTICS

Design considerations for nanotherapeutics in oncology

(2015) Triantafyllos Stylianopoulos et al.   Nanomedicine-Nanotechnology Biology and Medicine

Knocking down disease: a progress report on siRNA therapeutics

(2015) Anders Wittrup et al.   NATURE REVIEWS GENETICS

Development and Characterization of siRNA Lipoplexes: Effect of Different Lipids, In Vitro Evaluation in Cancerous Cell Lines and In Vivo Toxicity Study

(2014) Nirav Khatri et al.   AAPS PHARMSCITECH

Hypoxia-Targeted siRNA Delivery

(2014) F. Perche et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Matrix metalloproteinase 2-sensitive multifunctional polymeric micelles for tumor-specific co-delivery of siRNA and hydrophobic drugs

(2014) Lin Zhu et al.   BIOMATERIALS

Multifunctional, self-assembling anionic peptide-lipid nanocomplexes for targeted siRNA delivery

(2014) Aristides D. Tagalakis et al.   BIOMATERIALS

Phospholipid-modified PEI-based nanocarriers for in vivo siRNA therapeutics against multidrug-resistant tumors

(2014) S Essex et al.   GENE THERAPY

Designer lipids for drug delivery: From heads to tails

(2014) Aditya G. Kohli et al.   JOURNAL OF CONTROLLED RELEASE

Multifunctional, stimuli-sensitive nanoparticulate systems for drug delivery

(2014) Vladimir P. Torchilin   NATURE REVIEWS DRUG DISCOVERY

Establishment of Lipofection for Studying miRNA Function in Human Adipocytes

(2014) Eveliina Enlund et al.   PLoS One

Transferrin-Conjugated SNALPs Encapsulating 2′-O-Methylated miR-34a for the Treatment of Multiple Myeloma

(2014) Immacolata Scognamiglio et al.   Biomed Research International

Polymeric micelles containing reversibly phospholipid-modified anti-survivin siRNA: A promising strategy to overcome drug resistance in cancer

(2013) G. Salzano et al.   CANCER LETTERS

Enhanced hepatic delivery of siRNA and microRNA using oleic acid based lipid nanoparticle formulations

(2013) Xinmei Wang et al.   JOURNAL OF CONTROLLED RELEASE

Polycation liposomes as a vector for potential intracellular delivery of microRNA

(2013) Hidenori Ando et al.   JOURNAL OF GENE MEDICINE

MicroRNA 199b-5p delivery through stable nucleic acid lipid particles (SNALPs) in tumorigenic cell lines

(2013) Pasqualino de Antonellis et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Therapeutic Delivery of MicroRNA-29b by Cationic Lipoplexes for Lung Cancer

(2013) Yun Wu et al.   Molecular Therapy-Nucleic Acids

Hyaluronan grafted lipid-based nanoparticles as RNAi carriers for cancer cells

(2012) Dalit Landesman-Milo et al.   CANCER LETTERS

In Vivo Delivery Aspects of miRNA, shRNA and siRNA

(2012) N. I. Khatri et al.   CRITICAL REVIEWS IN THERAPEUTIC DRUG CARRIER SYSTEMS

Agitation during lipoplex formation harmonizes the interaction of siRNA to cationic liposomes

(2012) José Mario Barichello et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

RNA interference therapeutics for cancer: Challenges and opportunities (Review)

(2012) Roop Bora   Molecular Medicine Reports

Nanoparticle Delivery of Pooled siRNA for Effective Treatment of Non-Small Cell Lung Caner

(2012) Yang Yang et al.   MOLECULAR PHARMACEUTICS

Cetuximab-mediated Tumor Regression Depends on Innate and Adaptive Immune Responses

(2012) Xuanming Yang et al.   MOLECULAR THERAPY

In Vivo Sustained Release of siRNA from Solid Lipid Nanoparticles

(2011) Tatsiana Lobovkina et al.   ACS Nano

In Vivo Specific Delivery of c-Met siRNA to Glioblastoma Using Cationic Solid Lipid Nanoparticles

(2011) Juyoun Jin et al.   BIOCONJUGATE CHEMISTRY

Cationic solid lipid nanoparticles for co-delivery of paclitaxel and siRNA

(2011) Yong Hee Yu et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

MicroRNA Delivery by Cationic Lipoplexes for Lung Cancer Therapy

(2011) Yun Wu et al.   MOLECULAR PHARMACEUTICS

P-glycoprotein silencing with siRNA delivered by DOPE-modified PEI overcomes doxorubicin resistance in breast cancer cells

(2011) Gemma Navarro et al.   Nanomedicine

Effective Stabilization and Delivery of siRNA: Reversible siRNA−Phospholipid Conjugate in Nanosized Mixed Polymeric Micelles

(2010) Tiziana Musacchio et al.   BIOCONJUGATE CHEMISTRY

Oligonucleotide delivery in cancer therapy

(2010) Giuseppe De Rosa et al.   Expert Opinion on Drug Delivery

Reduced miR-34a Expression in Normal Cervical Tissues and Cervical Lesions With High-Risk Human Papillomavirus Infection

(2010) Baohua Li et al.   INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER

DC-Chol/DOPE cationic liposomes: A comparative study of the influence factors on plasmid pDNA and siRNA gene delivery

(2010) Yang Zhang et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Nanoparticles Targeted With NGR Motif Deliver c-myc siRNA and Doxorubicin for Anticancer Therapy

(2010) Yunching Chen et al.   MOLECULAR THERAPY

Rational design of cationic lipids for siRNA delivery

(2010) Sean C Semple et al.   NATURE BIOTECHNOLOGY

Nanoparticles evading the reticuloendothelial system: Role of the supported bilayer

(2009) Shyh-Dar Li et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Confirming the RNAi-mediated mechanism of action of siRNA-based cancer therapeutics in mice

(2009) Adam D. Judge et al.   JOURNAL OF CLINICAL INVESTIGATION

Biodegradable calcium phosphate nanoparticle with lipid coating for systemic siRNA delivery

(2009) Jun Li et al.   JOURNAL OF CONTROLLED RELEASE

Novel Cationic Lipid That Delivers siRNA and Enhances Therapeutic Effect in Lung Cancer Cells

(2009) Yunching Chen et al.   MOLECULAR PHARMACEUTICS

Novel cationic liposome formulation for the delivery of an oligonucleotide decoy to NF-κB into activated macrophages

(2008) G DEROSA et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

An efficient and low immunostimulatory nanoparticle formulation for systemic siRNA delivery to the tumor

(2008) Sumio Chono et al.   JOURNAL OF CONTROLLED RELEASE

Cationic Solid Lipid Nanoparticles Reconstituted from Low Density Lipoprotein Components for Delivery of siRNA

(2008) Hyun Ryoung Kim et al.   MOLECULAR PHARMACEUTICS

Efficient Oncogene Silencing and Metastasis Inhibition via Systemic Delivery of siRNA

(2008) Shyh-Dar Li et al.   MOLECULAR THERAPY

Intratracheal Versus Intravenous Liposomal Delivery of siRNA, Antisense Oligonucleotides and Anticancer Drug

(2008) Olga B. Garbuzenko et al.   PHARMACEUTICAL RESEARCH