Oligonucleotide delivery in cancer therapy

RNA Targeting Therapeutics: Molecular Mechanisms of Antisense Oligonucleotides as a Therapeutic Platform

(2010) C. Frank Bennett et al.   Annual Review of Pharmacology and Toxicology

Discovery and Development of Therapeutic Aptamers

(2010) P.R. Bouchard et al.   Annual Review of Pharmacology and Toxicology

Target specific tumor treatment by VEGF siRNA complexed with reducible polyethyleneimine–hyaluronic acid conjugate

(2010) Kitae Park et al.   BIOMATERIALS

Targeted Gene Silencing Using RGD-Labeled Chitosan Nanoparticles

(2010) H. D. Han et al.   CLINICAL CANCER RESEARCH

A non-covalent strategy combining cationic lipids and CPPs to enhance the delivery of splice correcting oligonucleotides

(2010) Sara Trabulo et al.   JOURNAL OF CONTROLLED RELEASE

Toxicity Pathway Focused Gene Expression Profiling of PEI-Based Polymers for Pulmonary Applications

(2010) Andrea Beyerle et al.   MOLECULAR PHARMACEUTICS

Rational Design of Immunostimulatory siRNAs

(2010) Michael P Gantier et al.   MOLECULAR THERAPY

Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles

(2010) Mark E. Davis et al.   NATURE

Rational design of cationic lipids for siRNA delivery

(2010) Sean C Semple et al.   NATURE BIOTECHNOLOGY

Pharmacological Inhibition of the Bcl-2 Family of Apoptosis Regulators as Cancer Therapy

(2010) Alan Richardson et al.   Current Molecular Pharmacology

Delivery of RNA interference therapeutics using polycation-based nanoparticles

(2009) Kenneth Alan Howard   ADVANCED DRUG DELIVERY REVIEWS

WT1 gene silencing by aerosol delivery of PEI–RNAi complexes inhibits B16-F10 lung metastases growth

(2009) D E Zamora-Avila et al.   CANCER GENE THERAPY

Toll-like Receptor 9 Activation of Signal Transducer and Activator of Transcription 3 Constrains Its Agonist-Based Immunotherapy

(2009) M. Kortylewski et al.   CANCER RESEARCH

Treatment with LL-37 Peptide Enhances Antitumor Effects Induced by CpG Oligodeoxynucleotides Against Ovarian Cancer

(2009) Chi-Mu Chuang et al.   HUMAN GENE THERAPY

Stability of siRNA polyplexes from poly(ethylenimine) and poly(ethylenimine)-g-poly(ethylene glycol) under in vivo conditions: Effects on pharmacokinetics and biodistribution measured by Fluorescence Fluctuation Spectroscopy and Single Photon Emission Computed Tomography (SPECT) imaging

(2009) Olivia M. Merkel et al.   JOURNAL OF CONTROLLED RELEASE

A Nucleolin-Targeted Multimodal Nanoparticle Imaging Probe for Tracking Cancer Cells Using an Aptamer

(2009) D. W. Hwang et al.   JOURNAL OF NUCLEAR MEDICINE

Novel Cationic Lipid That Delivers siRNA and Enhances Therapeutic Effect in Lung Cancer Cells

(2009) Yunching Chen et al.   MOLECULAR PHARMACEUTICS

The First Targeted Delivery of siRNA in Humans via a Self-Assembling, Cyclodextrin Polymer-Based Nanoparticle: From Concept to Clinic

(2009) Mark E. Davis   MOLECULAR PHARMACEUTICS

Antitumor Vectorized Oligonucleotides in a Model of Ewing Sarcoma: Unexpected Role of Nanoparticles

(2009) Hind Elhamess et al.   OLIGONUCLEOTIDES

Transferrin Receptor Targeted Lipopolyplexes for Delivery of Antisense Oligonucleotide G3139 in a Murine K562 Xenograft Model

(2009) Xulang Zhang et al.   PHARMACEUTICAL RESEARCH

Oligonucleotide decoy to NF-κB slowly released from PLGA microspheres reduces chronic inflammation in rat

(2009) Daniela De Stefano et al.   PHARMACOLOGICAL RESEARCH

Claudin-3 gene silencing with siRNA suppresses ovarian tumor growth and metastasis

(2009) Y.-H. Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Atu027, a Liposomal Small Interfering RNA Formulation Targeting Protein Kinase N3, Inhibits Cancer Progression

(2008) M. Aleku et al.   CANCER RESEARCH

Antisense, RNAi, and gene silencing strategies for therapy: Mission possible or impossible?

(2008) E RAYBURN et al.   DRUG DISCOVERY TODAY

Novel cationic liposome formulation for the delivery of an oligonucleotide decoy to NF-κB into activated macrophages

(2008) G DEROSA et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Folate-linked lipid-based nanoparticles for synthetic siRNA delivery in KB tumor xenografts

(2008) Takashi Yoshizawa et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Efficient Oncogene Silencing and Metastasis Inhibition via Systemic Delivery of siRNA

(2008) Shyh-Dar Li et al.   MOLECULAR THERAPY

Chemical Modification of siRNAs for In Vivo Use

(2008) Mark A. Behlke   OLIGONUCLEOTIDES