Exploring the mechanisms of action of human secretory RNase 3 and RNase 7 againstCandida albicans

Basal Cells Contribute to Innate Immunity of the Airway Epithelium through Production of the Antimicrobial Protein RNase 7

(2015) Gimano D. Amatngalim et al.   JOURNAL OF IMMUNOLOGY

Ribonucleases 6 and 7 have antimicrobial function in the human and murine urinary tract

(2015) Brian Becknell et al.   KIDNEY INTERNATIONAL

ZEBRA cell-penetrating peptide as an efficient delivery system inCandida albicans

(2014) Roberta Marchione et al.   Biotechnology Journal

Interplay between Candida albicans and the Antimicrobial Peptide Armory

(2014) Marc Swidergall et al.   EUKARYOTIC CELL

Cationic membrane-active peptides - anticancer and antifungal activity as well as penetration into human skin

(2014) Nhung Do et al.   EXPERIMENTAL DERMATOLOGY

Eosinophil Granule Proteins: Form and Function

(2014) K. Ravi Acharya et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Responses of Candida albicans to the human antimicrobial peptide LL-37

(2014) Pei-Wen Tsai et al.   JOURNAL OF MICROBIOLOGY

Functional Evolution of Ribonuclease Inhibitor: Insights from Birds and Reptiles

(2014) Jo E. Lomax et al.   JOURNAL OF MOLECULAR BIOLOGY

Two Human Host Defense Ribonucleases against Mycobacteria, the Eosinophil Cationic Protein (RNase 3) and RNase 7

(2013) David Pulido et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Contribution of Electrostatics to the Binding of Pancreatic-Type Ribonucleases to Membranes

(2013) Nadia K. Sundlass et al.   BIOCHEMISTRY

Peptide design for antimicrobial and immunomodulatory applications

(2013) Evan F. Haney et al.   BIOPOLYMERS

Towards the rational design of antimicrobial proteins

(2013) David Pulido et al.   FEBS Journal

Ribonuclease 7, an antimicrobial peptide upregulated during infection, contributes to microbial defense of the human urinary tract

(2013) John David Spencer et al.   KIDNEY INTERNATIONAL

An endogenous ribonuclease inhibitor regulates the antimicrobial activity of ribonuclease 7 in the human urinary tract

(2013) John D. Spencer et al.   KIDNEY INTERNATIONAL

A Novel Cell-Penetrating Peptide Derived from Human Eosinophil Cationic Protein

(2013) Shun-lung Fang et al.   PLoS One

Chemical-Functional Diversity in Cell-Penetrating Peptides

(2013) Sofie Stalmans et al.   PLoS One

A common landscape for membrane-active peptides

(2013) Nicholas B. Last et al.   PROTEIN SCIENCE

Candida albicanspathogenicity mechanisms

(2013) François L. Mayer et al.   Virulence

In SilicoPrediction andIn VitroCharacterization of Multifunctional Human RNase3

(2013) Pei-Chun Lien et al.   Biomed Research International

Insights into the Glycosaminoglycan-Mediated Cytotoxic Mechanism of Eosinophil Cationic Protein Revealed by NMR

(2012) M. Flor García-Mayoral et al.   ACS Chemical Biology

Structural determinants of the eosinophil cationic protein antimicrobial activity

(2012) Ester Boix et al.   BIOLOGICAL CHEMISTRY

The mammalian secreted RNases: Mechanisms of action in host defence

(2012) Sandeep K Gupta et al.   Innate Immunity

The sulfate-binding site structure of the human eosinophil cationic protein as revealed by a new crystal form

(2012) Ester Boix et al.   JOURNAL OF STRUCTURAL BIOLOGY

Inhibition of dermatophytes by the antimicrobial peptides human β-defensin-2, ribonuclease 7 and psoriasin

(2012) Peter Fritz et al.   MEDICAL MYCOLOGY

Structural and molecular insights into the mechanism of action of human angiogenin-ALS variants in neurons

(2012) Nethaji Thiyagarajan et al.   Nature Communications

Exploring New Biological Functions of Amyloids: Bacteria Cell Agglutination Mediated by Host Protein Aggregation

(2012) Marc Torrent et al.   PLoS Pathogens

Deciphering the Mode of Action of the Synthetic Antimicrobial Peptide Bac8c

(2011) E. C. Spindler et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Mechanism of Ribonuclease A Endocytosis: Analogies to Cell-Penetrating Peptides

(2011) Tzu-Yuan Chao et al.   BIOCHEMISTRY

Bovine Pancreatic Ribonuclease: Fifty Years of the First Enzymatic Reaction Mechanism

(2011) Claudi M. Cuchillo et al.   BIOCHEMISTRY

Role of unique basic residues in cytotoxic, antibacterial and antiparasitic activities of human eosinophil cationic protein

(2011) Anubha Singh et al.   BIOLOGICAL CHEMISTRY

Cationic antimicrobial peptides in clinical development, with special focus on thanatin and heliomicin

(2011) E. Andrès   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

Refining the Eosinophil Cationic Protein Antibacterial Pharmacophore by Rational Structure Minimization

(2011) Marc Torrent et al.   JOURNAL OF MEDICINAL CHEMISTRY

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Eosinophil Cationic Protein Aggregation: Identification of an N-Terminus Amyloid Prone Region

(2010) Marc Torrent et al.   BIOMACROMOLECULES

NMR Structural Determinants of Eosinophil Cationic Protein Binding to Membrane and Heparin Mimetics

(2010) María Flor García-Mayoral et al.   BIOPHYSICAL JOURNAL

Signalling pathways involved in ribonuclease-7 expression

(2010) Imran Mohammed et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Comparison of human RNase 3 and RNase 7 bactericidal action at the Gram-negative and Gram-positive bacterial cell wall

(2010) Marc Torrent et al.   FEBS Journal

Characterisation of the anti-microbial activity of bovine milk ribonuclease4 and ribonuclease5 (angiogenin)

(2010) Paul Harris et al.   INTERNATIONAL DAIRY JOURNAL

Outer Membrane Protein I ofPseudomonas aeruginosaIs a Target of Cationic Antimicrobial Peptide/Protein

(2010) Yu-Min Lin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Eosinophil cationic protein (ECP) can bind heparin and other glycosaminoglycans through its RNase active site

(2010) Marc Torrent et al.   JOURNAL OF MOLECULAR RECOGNITION

Comparison of the membrane interaction mechanism of two antimicrobial RNases: RNase 3/ECP and RNase 7

(2009) Marc Torrent et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Multifunctional host defense peptides: intracellular-targeting antimicrobial peptides

(2009) Pierre Nicolas   FEBS Journal

UV-B radiation induces the expression of antimicrobial peptides in human keratinocytes in vitro and in vivo

(2009) Regine Gläser et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Degradation by Stratum Corneum Proteases Prevents Endogenous RNase Inhibitor from Blocking Antimicrobial Activities of RNase 5 and RNase 7

(2009) Arby Abtin et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Antifungal Activities of Human Beta-Defensins HBD-1 to HBD-3 and Their C-Terminal Analogs Phd1 to Phd3

(2008) V. Krishnakumari et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Intracellular Routing of Cytotoxic Pancreatic-Type Ribonucleases

(2008) Antoni Benito et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Characterization of Molecular Interactions between Eosinophil Cationic Protein and Heparin

(2008) Tan-chi Fan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RNase A ribonucleases and host defense: an evolving story

(2008) Helene F. Rosenberg   JOURNAL OF LEUKOCYTE BIOLOGY

Candida albicans Cell Wall Proteins

(2008) W. L. Chaffin   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

The Antimicrobial Peptide Histatin-5 Causes a Spatially Restricted Disruption on the Candida albicans Surface, Allowing Rapid Entry of the Peptide into the Cytoplasm

(2008) A. Brian Mochon et al.   PLoS Pathogens