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Title
CAR T Cell Therapy: A Game Changer in Cancer Treatment
Authors
Keywords
-
Journal
Journal of Immunology Research
Volume 2016, Issue -, Pages 1-10
Publisher
Hindawi Limited
Online
2016-05-20
DOI
10.1155/2016/5474602
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- (2016) Anthony Walker et al. BIOCHEMICAL SOCIETY TRANSACTIONS
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- (2016) Alexandre Juillerat et al. Scientific Reports
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- (2015) Zeguo Zhao et al. CANCER CELL
- Towards a commercial process for the manufacture of genetically modified T cells for therapy
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- ErbB-targeted CAR T-cell immunotherapy of cancer
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- (2015) Maarten A. Ligtenberg et al. JOURNAL OF IMMUNOLOGY
- Chimeric Antigen Receptor– and TCR-Modified T Cells Enter Main Street and Wall Street
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- (2015) D Sommermeyer et al. LEUKEMIA
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- (2013) Sunitha Kakarla et al. MOLECULAR THERAPY
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- (2013) Cor HJ Lamers et al. MOLECULAR THERAPY
- Perspective: Assembly line immunotherapy
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- (2013) Stephan A. Grupp et al. NEW ENGLAND JOURNAL OF MEDICINE
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- (2013) V. D. Fedorov et al. Science Translational Medicine
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- (2013) E. Lanitis et al. Cancer Immunology Research
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- (2013) Zakaria Grada et al. Molecular Therapy-Nucleic Acids
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- (2012) B. G. Till et al. BLOOD
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- (2012) N. Cieri et al. BLOOD
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- (2012) Christopher A. Klebanoff et al. JOURNAL OF IMMUNOTHERAPY
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- (2012) Christopher C Kloss et al. NATURE BIOTECHNOLOGY
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- (2012) J. Scholler et al. Science Translational Medicine
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- (2012) David E. Gilham et al. TRENDS IN MOLECULAR MEDICINE
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- (2012) Virna Marin et al. Human Gene Therapy Methods
- Generation of CD19-chimeric antigen receptor modified CD8+ T cells derived from virus-specific central memory T cells
- (2011) S. Terakura et al. BLOOD
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- (2011) C. U. Louis et al. BLOOD
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- (2011) Pawel Muranski et al. IMMUNITY
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- (2011) M. Kalos et al. Science Translational Medicine
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- (2010) Richard A Morgan et al. MOLECULAR THERAPY
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- (2010) C. M. Paulos et al. Science Translational Medicine
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- (2009) H. E. Heslop et al. BLOOD
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- (2009) K Birkholz et al. GENE THERAPY
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- (2009) Syam Tammana et al. HUMAN GENE THERAPY
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- (2009) Daniel Hollyman et al. JOURNAL OF IMMUNOTHERAPY
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- (2009) Michael C. Milone et al. MOLECULAR THERAPY
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- (2008) S. Newrzela et al. BLOOD
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- (2008) Martin A Pule et al. NATURE MEDICINE
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