Dendritic Cells under Hypoxia: How Oxygen Shortage Affects the Linkage between Innate and Adaptive Immunity

Hypoxia-inducible factor 1 in dendritic cells is crucial for the activation of protective regulatory T cells in murine colitis

(2015) K Flück et al.   Mucosal Immunology

IRF-5-Mediated Inflammation Limits CD8+ T Cell Expansion by Inducing HIF-1α and Impairing Dendritic Cell Functions during Leishmania Infection

(2015) Akil Hammami et al.   PLoS Pathogens

HIF-α/MIF and NF-κB/IL-6 Axes Contribute to the Recruitment of CD11b+Gr-1+ Myeloid Cells in Hypoxic Microenvironment of HNSCC

(2015) Guiquan Zhu et al.   NEOPLASIA

Short-Term Hypoxia Enhances the Migratory Capability of Dendritic Cell Through HIF-1α and PI3K/Akt Pathway

(2014) Irene Filippi et al.   JOURNAL OF CELLULAR PHYSIOLOGY

IL-10: The Master Regulator of Immunity to Infection

(2014) Kevin N. Couper et al.   JOURNAL OF IMMUNOLOGY

Hypoxia and Hypoxia-Inducible Factor-1  Modulate Lipopolysaccharide-Induced Dendritic Cell Activation and Function

(2014) J. Jantsch et al.   JOURNAL OF IMMUNOLOGY

Silver Nanoparticle–Induced hMSC Proliferation Is Associated with HIF-1α-Mediated Upregulation of IL-8 Expression

(2014) Sung Kyu Jung et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Role of hypoxia inducible factor-1α for interferon synthesis in mouse dendritic cells

(2013) Regina Wobben et al.   BIOLOGICAL CHEMISTRY

Chronic hypoxia reprograms human immature dendritic cells by inducing a proinflammatory phenotype and TREM-1 expression

(2013) Daniele Pierobon et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

HIF-1α influences myeloid cell antigen presentation and response to subcutaneous OVA vaccination

(2013) Tamara Bhandari et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Succinate is an inflammatory signal that induces IL-1β through HIF-1α

(2013) G. M. Tannahill et al.   NATURE

Decisions About Dendritic Cells: Past, Present, and Future

(2012) Ralph M. Steinman   Annual Review of Immunology

HIF-1  is a negative regulator of plasmacytoid DC development in vitro and in vivo

(2012) A. Weigert et al.   BLOOD

Influence of hypoxia-inducible factor 1α on dendritic cell differentiation and migration

(2012) Theresa Köhler et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Role of reactive oxygen species in the regulation of HIF-1 by prolyl hydroxylase 2 under mild hypoxia

(2012) Helene Niecknig et al.   FREE RADICAL RESEARCH

Dendritic cell reprogramming by the hypoxic environment

(2012) Maria Carla Bosco et al.   IMMUNOBIOLOGY

The hypoxic environment reprograms the cytokine/chemokine expression profile of human mature dendritic cells

(2012) Fabiola Blengio et al.   IMMUNOBIOLOGY

Inclusive estimation of complex antigen presentation functions of monocyte-derived dendritic cells differentiated under normoxia and hypoxia conditions

(2011) Toshitatsu Ogino et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Toll-like receptor activation and hypoxia use distinct signaling pathways to stabilize hypoxia-inducible factor 1α (HIF1A) and result in differential HIF1A-dependent gene expression

(2011) Jonathan Jantsch et al.   JOURNAL OF LEUKOCYTE BIOLOGY

In vivo T Cell Activation in Lymphoid Tissues is Inhibited in the Oxygen-Poor Microenvironment

(2011) Akio Ohta et al.   Frontiers in Immunology

Hypoxia modulates the gene expression profile of immunoregulatory receptors in human mature dendritic cells: identification of TREM-1 as a novel hypoxic marker in vitro and in vivo

(2010) M. C. Bosco et al.   BLOOD

Hypoxia-inducible factor 2α regulates macrophage function in mouse models of acute and tumor inflammation

(2010) Hongxia Z. Imtiyaz et al.   JOURNAL OF CLINICAL INVESTIGATION

Effects of TLR Agonists on the Hypoxia-Regulated Transcription Factor HIF-1α and Dendritic Cell Maturation under Normoxic Conditions

(2010) Rolf Spirig et al.   PLoS One

Nitric oxide causes macrophage migration via the HIF-1-stimulated small GTPases Cdc42 and Rac1

(2009) Jie Zhou et al.   FREE RADICAL BIOLOGY AND MEDICINE

HIF-dependent induction of adenosine receptor A2b skews human dendritic cells to a Th2-stimulating phenotype under hypoxia

(2009) Meixiang Yang et al.   IMMUNOLOGY AND CELL BIOLOGY

Activation of the Oxidative Stress Pathway by HIV-1 Vpr Leads to Induction of Hypoxia-inducible Factor 1α Expression

(2009) Satish L. Deshmane et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of hypoxia-inducible factor-1α by NF-κB

(2008) Patrick van Uden et al.   BIOCHEMICAL JOURNAL

Monocytes and dendritic cells in a hypoxic environment: Spotlights on chemotaxis and migration

(2008) Maria Carla Bosco et al.   IMMUNOBIOLOGY

Human dendritic cells differentiated in hypoxia down-modulate antigen uptake and change their chemokine expression profile

(2008) Angela Rita Elia et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Hypoxia stimulus: An adaptive immune response during dendritic cell maturation

(2008) I. Rama et al.   KIDNEY INTERNATIONAL

Transcriptome of Hypoxic Immature Dendritic Cells: Modulation of Chemokine/Receptor Expression

(2008) A. Ricciardi et al.   MOLECULAR CANCER RESEARCH

NF-κB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1α

(2008) Jordi Rius et al.   NATURE