Neuropharmacology of New Psychoactive Substances (NPS): Focus on the Rewarding and Reinforcing Properties of Cannabimimetics and Amphetamine-Like Stimulants

Withdrawal Phenomena and Dependence Syndrome After the Consumption of „Spice Gold“

(2018) Ulrich S. Zimmermann et al.   Deutsches Arzteblatt International

Effects and Risks Associated with Novel Psychoactive Substances

(2018) Nicolas Hohmann et al.   Deutsches Arzteblatt International

Native CB1 receptor affinity, intrinsic activity and accumbens shell dopamine stimulant properties of third generation SPICE/K2 cannabinoids: BB-22, 5F-PB-22, 5F-AKB-48 and STS-135

(2016) Maria Antonietta De Luca et al.   NEUROPHARMACOLOGY

Effect of JWH-250, JWH-073 and their interaction on “tetrad”, sensorimotor, neurological and neurochemical responses in mice

(2016) Andrea Ossato et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

New Psychoactive Substances

(2016) Jessica Welter-Luedeke et al.   THERAPEUTIC DRUG MONITORING

The new stimulant designer compound pentedrone exhibits rewarding properties and affects dopaminergic activity

(2015) Ji-Young Hwang et al.   ADDICTION BIOLOGY

Synthetic Cannabinoids

(2015) Brooke Mills et al.   AMERICAN JOURNAL OF THE MEDICAL SCIENCES

An overview of recent developments in the analytical detection of new psychoactive substances (NPSs)

(2015) Jamie P. Smith et al.   ANALYST

The hallucinogenic world of tryptamines: an updated review

(2015) Ana Margarida Araújo et al.   ARCHIVES OF TOXICOLOGY

Δ9-Tetrahydrocannabinol-like effects of novel synthetic cannabinoids found on the gray market

(2015) Michael B. Gatch et al.   BEHAVIOURAL PHARMACOLOGY

Prevalence of use and acute toxicity associated with the use of NBOMe drugs

(2015) David M. Wood et al.   CLINICAL TOXICOLOGY

Synthetic Cathinones: A New Public Health Problem

(2015) Laurent Karila et al.   Current Neuropharmacology

Recreational Use, Analysis and Toxicity of Tryptamines

(2015) Roberta Tittarelli et al.   Current Neuropharmacology

Recreational phenethylamine poisonings reported to a French poison control center

(2015) Gaël Le Roux et al.   DRUG AND ALCOHOL DEPENDENCE

Effects of acute and repeated dosing of the synthetic cannabinoid CP55,940 on intracranial self-stimulation in mice

(2015) Travis W. Grim et al.   DRUG AND ALCOHOL DEPENDENCE

Self-reported use of novel psychoactive substances in a US nationally representative survey: Prevalence, correlates, and a call for new survey methods to prevent underreporting

(2015) Joseph J. Palamar et al.   DRUG AND ALCOHOL DEPENDENCE

Monitoring new psychoactive substances (NPS) in The Netherlands: Data from the drug market and the Poisons Information Centre

(2015) Laura Hondebrink et al.   DRUG AND ALCOHOL DEPENDENCE

Evaluation of the abuse potential of AM281, a new synthetic cannabinoid CB1 receptor antagonist

(2015) Chrislean Jun Botanas et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Psyclones: a roller coaster of life? Hidden synthetic cannabinoids and stimulants in apparently harmless products

(2015) Rita Santacroce et al.   HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL

Novel psychoactive substances: use and knowledge among adolescents and young adults in urban and rural areas

(2015) Giovanni Martinotti et al.   HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL

The neurotoxicity of amphetamines during the adolescent period

(2015) Armanda Teixeira-Gomes et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

Driving under the influence of synthetic phenethylamines: a case series

(2015) Alexandra Maas et al.   INTERNATIONAL JOURNAL OF LEGAL MEDICINE

Synthetic Cannabinoid Abuse in Adolescents: A Case Series

(2015) Gulser Esen Besli et al.   JOURNAL OF EMERGENCY MEDICINE

3,4-Methylenedioxypyrovalerone prevents while methylone enhances methamphetamine-induced damage to dopamine nerve endings: β-ketoamphetamine modulation of neurotoxicity by the dopamine transporter

(2015) John H. Anneken et al.   JOURNAL OF NEUROCHEMISTRY

The adverse health effects of synthetic cannabinoids with emphasis on psychosis-like effects

(2015) Jan van Amsterdam et al.   JOURNAL OF PSYCHOPHARMACOLOGY

The influence of cannabinoids on learning and memory processes of the dorsal striatum

(2015) Jarid Goodman et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Novel halogenated derivates of JWH-018: Behavioral and binding studies in mice

(2015) A. Vigolo et al.   NEUROPHARMACOLOGY

Stimulation of in vivo dopamine transmission and intravenous self-administration in rats and mice by JWH-018, a Spice cannabinoid

(2015) M.A. De Luca et al.   NEUROPHARMACOLOGY

Reinforcing and neurochemical effects of the “bath salts” constituents 3,4-methylenedioxypyrovalerone (MDPV) and 3,4-methylenedioxy-N-methylcathinone (methylone) in male rats

(2015) Charles W. Schindler et al.   PSYCHOPHARMACOLOGY

In vivo potency and efficacy of the novel cathinone α-pyrrolidinopentiophenone and 3,4-methylenedioxypyrovalerone: self-administration and locomotor stimulation in male rats

(2015) Shawn M. Aarde et al.   PSYCHOPHARMACOLOGY

Novel psychoactive substances (designer drugs): overview and pharmacology of modulators of monoamine signaling

(2015) M Liechti   SWISS MEDICAL WEEKLY

Novel psychoactive substances of interest for psychiatry

(2015) Fabrizio Schifano et al.   World Psychiatry

LC-QTOF-MS as a superior strategy to immunoassay for the comprehensive analysis of synthetic cannabinoids in urine

(2014) Robert Kronstrand et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Δ9-Tetrahydrocannabinol-like discriminative stimulus effects of compounds commonly found in K2/Spice

(2014) Michael B. Gatch et al.   BEHAVIOURAL PHARMACOLOGY

Pharmacological profiles of aminoindanes, piperazines, and pipradrol derivatives

(2014) Linda D. Simmler et al.   BIOCHEMICAL PHARMACOLOGY

The European Drug Emergencies Network (Euro-DEN)

(2014) D. M. Wood et al.   CLINICAL TOXICOLOGY

Emerging drugs of abuse

(2014) Michael E. Nelson et al.   DM DISEASE-A-MONTH

Monitoring drug markets in the Internet age and the evolution of drug monitoring systems in Australia

(2014) Lucy Burns et al.   Drug Testing and Analysis

Detection of new psychoactive substance use among emergency room patients: Results from the Swedish STRIDA project

(2014) Anders Helander et al.   FORENSIC SCIENCE INTERNATIONAL

Emergence of New Classes of Recreational Drugs—Synthetic Cannabinoids and Cathinones

(2014) Vikas Khullar et al.   JOURNAL OF GENERAL INTERNAL MEDICINE

Enhanced Endocannabinoid-Mediated Modulation of Rostromedial Tegmental Nucleus Drive onto Dopamine Neurons in Sardinian Alcohol-Preferring Rats

(2014) M. Melis et al.   JOURNAL OF NEUROSCIENCE

Designer psychostimulants: Pharmacology and differences

(2014) Leslie Iversen et al.   NEUROPHARMACOLOGY

In vivo effects of synthetic cannabinoids JWH-018 and JWH-073 and phytocannabinoid Δ9-THC in mice: Inhalation versus intraperitoneal injection

(2014) R. Marshell et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

25C-NBOMe: Preliminary Data on Pharmacology, Psychoactive Effects, and Toxicity of a New Potent and Dangerous Hallucinogenic Drug

(2014) Francesco Saverio Bersani et al.   Biomed Research International

Cannabinoid Regulation of Brain Reward Processing with an Emphasis on the Role of CB1 Receptors: A Step Back into the Future

(2014) George Panagis et al.   Frontiers in Psychiatry

Khat and synthetic cathinones: a review

(2013) Maria João Valente et al.   ARCHIVES OF TOXICOLOGY

Update on 1-benzylpiperazine (BZP) party pills

(2013) Márcia Sá Monteiro et al.   ARCHIVES OF TOXICOLOGY

Locomotor stimulant and discriminative stimulus effects of ‘bath salt’ cathinones

(2013) Michael B. Gatch et al.   BEHAVIOURAL PHARMACOLOGY

Substituted methcathinones differ in transporter and receptor interactions

(2013) Amy J. Eshleman et al.   BIOCHEMICAL PHARMACOLOGY

Psychoactive substances—Some new, some old: A scan of the situation in the U.S.

(2013) Jane Carlisle Maxwell   DRUG AND ALCOHOL DEPENDENCE

The K2/Spice Phenomenon: emergence, identification, legislation and metabolic characterization of synthetic cannabinoids in herbal incense products

(2013) Lisa K. Brents et al.   DRUG METABOLISM REVIEWS

Changes in the prevalence of new psychoactive substances before and after the introduction of the generic scheduling of synthetic cannabinoids in Japan

(2013) Ruri Kikura-Hanajiri et al.   Drug Testing and Analysis

MDAI (5,6-methylenedioxy-2-aminoindane; 6,7-dihydro-5H-cyclopenta[f][1,3]benzodioxol-6-amine; ‘sparkle’; ‘mindy’) toxicity: a brief overview and update

(2013) John M Corkery et al.   HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL

“Spiceophrenia”: a systematic overview of “Spice”-related psychopathological issues and a case report

(2013) Duccio Papanti et al.   HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL

Consumption of new psychoactive substances in a Spanish sample of research chemical users

(2013) Débora González et al.   HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL

The 12-month prevalence and nature of adverse experiences resulting in emergency medical presentations associated with the use of synthetic cannabinoid products

(2013) Adam R. Winstock et al.   HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL

Novel psychoactive substances as a novel challenge for health professionals: results from an Italian survey

(2013) Pierluigi Simonato et al.   HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL

A review of clinical manifestations in adolescent and young adults after use of synthetic cannabinoids

(2013) Tracy L. Brewer et al.   Journal for Specialists in Pediatric Nursing

Identification and Structural Elucidation of Four Cannabimimetic Compounds (RCS-4, AM-2201, JWH-203 and JWH-210) in Seized Products

(2013) Raphael Denooz et al.   JOURNAL OF ANALYTICAL TOXICOLOGY

Bath salts and synthetic cathinones: An emerging designer drug phenomenon

(2013) Christopher L. German et al.   LIFE SCIENCES

Moving around the molecule: Relationship between chemical structure and in vivo activity of synthetic cannabinoids

(2013) Jenny L. Wiley et al.   LIFE SCIENCES

The novel recreational drug 3,4-methylenedioxypyrovalerone (MDPV) is a potent psychomotor stimulant: Self-administration and locomotor activity in rats

(2013) S.M. Aarde et al.   NEUROPHARMACOLOGY

The effects of benzofury (5-APB) on the dopamine transporter and 5-HT2-dependent vasoconstriction in the rat

(2013) Patrick Dawson et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Behavioral and neurochemical pharmacology of six psychoactive substituted phenethylamines: mouse locomotion, rat drug discrimination and in vitro receptor and transporter binding and function

(2013) Amy J. Eshleman et al.   PSYCHOPHARMACOLOGY

Spicing things up: synthetic cannabinoids

(2013) Max Spaderna et al.   PSYCHOPHARMACOLOGY

Identification of novel psychoactive drug use in Sweden based on laboratory analysis – initial experiences from the STRIDA project

(2013) Anders Helander et al.   SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION

Acute toxicity due to the confirmed consumption of synthetic cannabinoids: clinical and laboratory findings

(2012) Maren Hermanns-Clausen et al.   ADDICTION

Potent rewarding and reinforcing effects of the synthetic cathinone 3,4-methylenedioxypyrovalerone (MDPV)

(2012) Lucas R. Watterson et al.   ADDICTION BIOLOGY

Synthetic Cathinones (Bath Salts): Legal Status and Patterns of Abuse

(2012) Jennifer A Fass et al.   ANNALS OF PHARMACOTHERAPY

Pharmacological characterization of designer cathinonesin vitro

(2012) LD Simmler et al.   BRITISH JOURNAL OF PHARMACOLOGY

A Major Glucuronidated Metabolite of JWH-018 Is a Neutral Antagonist at CB1 Receptors

(2012) Kathryn A. Seely et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Psychoactive “bath salts”: Not so soothing

(2012) Michael H. Baumann et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Neurochemical profiles of some novel psychoactive substances

(2012) Les Iversen et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Dose-Related Modulation of Event-Related Potentials to Novel and Target Stimuli by Intravenous Δ9-THC in Humans

(2012) Deepak Cyril D'Souza et al.   NEUROPSYCHOPHARMACOLOGY

Effects of synthetic cathinones contained in “bath salts” on motor behavior and a functional observational battery in mice

(2012) Julie A. Marusich et al.   NEUROTOXICOLOGY

Effect of Ambient Temperature on the Thermoregulatory and Locomotor Stimulant Effects of 4-Methylmethcathinone in Wistar and Sprague-Dawley Rats

(2012) M. Jerry Wright et al.   PLoS One

Identifying emerging trends in recreational drug use; outcomes from the Psychonaut Web Mapping Project

(2012) Paolo Deluca et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Synthetic cathinones: Chemistry, pharmacology and toxicology of a new class of designer drugs of abuse marketed as “bath salts” or “plant food”

(2012) M. Coppola et al.   TOXICOLOGY LETTERS

The “New” Marijuana

(2011) Daina L Wells et al.   ANNALS OF PHARMACOTHERAPY

Synthetic cannabinoid JWH-018 and psychosis: An explorative study

(2011) Susanna Every-Palmer   DRUG AND ALCOHOL DEPENDENCE

1-Pentyl-3-phenylacetylindoles and JWH-018 share in vivo cannabinoid profiles in mice

(2011) Jenny L. Wiley et al.   DRUG AND ALCOHOL DEPENDENCE

Cathinone derivatives: A review of their chemistry, pharmacology and toxicology

(2011) John P. Kelly   Drug Testing and Analysis

CP47,497-C8 and JWH073, commonly found in ‘Spice’ herbal blends, are potent and efficacious CB1 cannabinoid receptor agonists

(2011) Brady K. Atwood et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Desoxypipradrol is more potent than cocaine on evoked dopamine efflux in the nucleus accumbens

(2011) Colin Davidson et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Marijuana-based Drugs: Innovative Therapeutics or Designer Drugs of Abuse?

(2011) K. A. Seely et al.   MOLECULAR INTERVENTIONS

Endocannabinoid-mediated synaptic plasticity and addiction-related behavior

(2011) Nimish Sidhpura et al.   NEUROPHARMACOLOGY

Cannabinoid facilitation of behavioral and biochemical hedonic taste responses

(2011) M.A. De Luca et al.   NEUROPHARMACOLOGY

Phase I Hydroxylated Metabolites of the K2 Synthetic Cannabinoid JWH-018 Retain In Vitro and In Vivo Cannabinoid 1 Receptor Affinity and Activity

(2011) Lisa K. Brents et al.   PLoS One

Beyond THC: The New Generation of Cannabinoid Designer Drugs

(2011) Liana Fattore et al.   Frontiers in Behavioral Neuroscience

Chronic WIN55,212-2 elicits sustained and conditioned increases in intracranial self-stimulation thresholds in the rat

(2010) Maria Mavrikaki et al.   BEHAVIOURAL BRAIN RESEARCH

JWH018, a common constituent of ‘Spice’ herbal blends, is a potent and efficacious cannabinoid CB1receptor agonist

(2010) Brady K Atwood et al.   BRITISH JOURNAL OF PHARMACOLOGY

Overview of Amphetamine-Type Stimulant Mortality Data – UK, 1997–2007

(2010) Fabrizio Schifano et al.   NEUROPSYCHOBIOLOGY

Dimethyltryptamine and other hallucinogenic tryptamines exhibit substrate behavior at the serotonin uptake transporter and the vesicle monoamine transporter

(2009) Nicholas V. Cozzi et al.   JOURNAL OF NEURAL TRANSMISSION

Neurocircuitry of Addiction

(2009) George F Koob et al.   NEUROPSYCHOPHARMACOLOGY

Comparison of the discriminative stimulus effects of dimethyltryptamine with different classes of psychoactive compounds in rats

(2009) Michael B. Gatch et al.   PSYCHOPHARMACOLOGY

The Hallucinogen N,N-Dimethyltryptamine (DMT) Is an Endogenous Sigma-1 Receptor Regulator

(2009) D. Fontanilla et al.   SCIENCE

Δ9-Tetrahydrocannabinol Induces Dopamine Release in the Human Striatum

(2008) Matthijs G Bossong et al.   NEUROPSYCHOPHARMACOLOGY

Locomotor stimulation produced by 3,4-methylenedioxymethamphetamine (MDMA) is correlated with dialysate levels of serotonin and dopamine in rat brain

(2008) Michael H. Baumann et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

“Research Chemicals”: Tryptamine and Phenethylamine Use Among High-Risk Youth

(2008) Bill Sanders et al.   SUBSTANCE USE & MISUSE

Substance Abuse Among Adolescents

(2008) Steve Sussman et al.   SUBSTANCE USE & MISUSE

The behavioral pharmacology of hallucinogens

(2007) William E. Fantegrossi et al.   BIOCHEMICAL PHARMACOLOGY

Identification of the sites of 2-arachidonoylglycerol synthesis and action imply retrograde endocannabinoid signaling at both GABAergic and glutamatergic synapses in the ventral tegmental area

(2007) Ferenc Mátyás et al.   NEUROPHARMACOLOGY